Endogenous human CaMKII inhibitory protein suppresses tumor growth by inducing cell cycle arrest and apoptosis through down-regulation of the phosphatidylinositide 3-kinase/Akt/HDM2 pathway.
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Identifying microRNA/mRNA dysregulations in ovarian cancerStructure of the CaMKIIdelta/calmodulin complex reveals the molecular mechanism of CaMKII kinase activationThe emerging role of CaMKII in cancerE2/ER β Enhances Calcineurin Protein Degradation and PI3K/Akt/MDM2 Signal Transduction to Inhibit ISO-Induced Myocardial Cell Apoptosis.Calmodulin-an often-ignored signal in osteoclasts.Functional expression of TWEAK and the receptor Fn14 in human malignant ovarian tumors: possible implication for ovarian tumor intervention.The multifunctional Ca2+/calmodulin-dependent kinase II delta (CaMKIIdelta) controls neointima formation after carotid ligation and vascular smooth muscle cell proliferation through cell cycle regulation by p21.Calcium signals inhibition sensitizes ovarian carcinoma cells to anti-Bcl-xL strategies through Mcl-1 down-regulation.The metabotropic glutamate receptor activates the lipid kinase PI3K in Drosophila motor neurons through the calcium/calmodulin-dependent protein kinase II and the nonreceptor tyrosine protein kinase DFakThe growth and aggressive behavior of human osteosarcoma is regulated by a CaMKII-controlled autocrine VEGF signaling mechanismCaMKII in cerebral ischemia.IRBIT controls apoptosis by interacting with the Bcl-2 homolog, Bcl2l10, and by promoting ER-mitochondria contact.Ion channels and transporters in cancer. 1. Ion channels and cell proliferation in cancer.Cyclin-dependent kinase inhibitor 3 (CDKN3) novel cell cycle computational network between human non-malignancy associated hepatitis/cirrhosis and hepatocellular carcinoma (HCC) transformation.RUNX3 and CAMK2N1 hypermethylation as prognostic marker for epithelial ovarian cancer.Transcriptome meta-analysis reveals dysregulated pathways in nasopharyngeal carcinoma.Kv3.4 potassium channel-mediated electrosignaling controls cell cycle and survival of irradiated leukemia cells.Ca2+/calmodulin-dependent protein kinase II regulates colon cancer proliferation and migration via ERK1/2 and p38 pathways.Functional Analyses of RUNX3 and CaMKIINα in Ovarian Cancer Cell Lines Reveal Tumor-Suppressive Functions for CaMKIINα and Dichotomous Roles for RUNX3 Transcript Variants.Human liver regeneration is characterized by the coordinated expression of distinct microRNA governing cell cycle fate.Characterization of the rat cerebrospinal fluid proteome following acute cerebral ischemia using an aptamer-based proteomic technology.
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Endogenous human CaMKII inhibitory protein suppresses tumor growth by inducing cell cycle arrest and apoptosis through down-regulation of the phosphatidylinositide 3-kinase/Akt/HDM2 pathway.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 08 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Endogenous human CaMKII inhibi ...... ide 3-kinase/Akt/HDM2 pathway.
@en
Endogenous human CaMKII inhibi ...... ide 3-kinase/Akt/HDM2 pathway.
@nl
type
label
Endogenous human CaMKII inhibi ...... ide 3-kinase/Akt/HDM2 pathway.
@en
Endogenous human CaMKII inhibi ...... ide 3-kinase/Akt/HDM2 pathway.
@nl
prefLabel
Endogenous human CaMKII inhibi ...... ide 3-kinase/Akt/HDM2 pathway.
@en
Endogenous human CaMKII inhibi ...... ide 3-kinase/Akt/HDM2 pathway.
@nl
P2093
P2860
P356
P1476
Endogenous human CaMKII inhibi ...... ide 3-kinase/Akt/HDM2 pathway.
@en
P2093
Chunmei Wang
Haijun Zhong
Qinghua Zhang
Qingqing Wang
Shenglin Ma
Xuetao Cao
Yunshan Yang
P2860
P304
24773-24782
P356
10.1074/JBC.M109.028621
P407
P577
2009-07-08T00:00:00Z