Suppression of a sec63 mutation identifies a novel component of the yeast endoplasmic reticulum translocation apparatus.
about
The yeast RER2 gene, identified by endoplasmic reticulum protein localization mutations, encodes cis-prenyltransferase, a key enzyme in dolichol synthesisTransport route for synaptobrevin via a novel pathway of insertion into the endoplasmic reticulum membraneSec72p contributes to the selective recognition of signal peptides by the secretory polypeptide translocation complex.Genetic interactions between KAR7/SEC71, KAR8/JEM1, KAR5, and KAR2 during nuclear fusion in Saccharomyces cerevisiaeRer1p, a retrieval receptor for endoplasmic reticulum membrane proteins, is dynamically localized to the Golgi apparatus by coatomerThe homologue of mammalian SPC12 is important for efficient signal peptidase activity in Saccharomyces cerevisiae.Disruption of YHC8, a member of the TSR1 gene family, reveals its direct involvement in yeast protein translocation.Rer1p as common machinery for the endoplasmic reticulum localization of membrane proteins.SMS1, a high-copy suppressor of the yeast mas6 mutant, encodes an essential inner membrane protein required for mitochondrial protein import.A yeast DnaJ homologue, Scj1p, can function in the endoplasmic reticulum with BiP/Kar2p via a conserved domain that specifies interactions with Hsp70sA second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiaeKAR5 encodes a novel pheromone-inducible protein required for homotypic nuclear fusion.A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposomeEfficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocationStage- and ribosome-specific alterations in nascent chain-Sec61p interactions accompany translocation across the ER membraneThe lumenal domain of Sec63p stimulates the ATPase activity of BiP and mediates BiP recruitment to the translocon in Saccharomyces cerevisiaeER membrane protein complex required for nuclear fusionThe uterine expression of SEC63 gene is up-regulated at implantation sites in association with the decidualization during the early pregnancy in mice.Rer1p, a retrieval receptor for ER membrane proteins, recognizes transmembrane domains in multiple modes.Null mutations in a Nudix gene, ygdP, implicate an alarmone response in a novel suppression of hybrid jamming.Nonlethal sec71-1 and sec72-1 mutations eliminate proteins associated with the Sec63p-BiP complex from S. cerevisiaeMechanism of polypeptide translocation into the endoplasmic reticulum.Sec66-Dependent Regulation of Yeast Spindle-Pole Body Duplication Through Pom152.Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER.Determining the topology of an integral membrane protein.
P2860
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P2860
Suppression of a sec63 mutation identifies a novel component of the yeast endoplasmic reticulum translocation apparatus.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1993
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Suppression of a sec63 mutatio ...... culum translocation apparatus.
@en
Suppression of a sec63 mutatio ...... culum translocation apparatus.
@nl
type
label
Suppression of a sec63 mutatio ...... culum translocation apparatus.
@en
Suppression of a sec63 mutatio ...... culum translocation apparatus.
@nl
prefLabel
Suppression of a sec63 mutatio ...... culum translocation apparatus.
@en
Suppression of a sec63 mutatio ...... culum translocation apparatus.
@nl
P2860
P356
P1476
Suppression of a sec63 mutatio ...... culum translocation apparatus.
@en
P2093
P2860
P304
P356
10.1091/MBC.4.9.919
P577
1993-09-01T00:00:00Z