Genetic interactions between KAR2 and SEC63, encoding eukaryotic homologues of DnaK and DnaJ in the endoplasmic reticulum.
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Characterization of a brain-enriched chaperone, MRJ, that inhibits Huntingtin aggregation and toxicity independentlyThe SANT2 domain of the murine tumor cell DnaJ-like protein 1 human homologue interacts with alpha1-antichymotrypsin and kinetically interferes with its serpin inhibitory activityMultiple interactions of components mediating preprotein translocation across the inner mitochondrial membraneMammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclatureInteraction of murine BiP/GRP78 with the DnaJ homologue MTJ1A role for the DnaJ homologue Scj1p in protein folding in the yeast endoplasmic reticulum.Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation.Cooperation of the molecular chaperone Ydj1 with specific Hsp70 homologs to suppress protein aggregation.Genetic interactions between KAR7/SEC71, KAR8/JEM1, KAR5, and KAR2 during nuclear fusion in Saccharomyces cerevisiaeVac8p, a vacuolar protein with armadillo repeats, functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuoleSec63p and Kar2p are required for the translocation of SRP-dependent precursors into the yeast endoplasmic reticulum in vivo.Saccharomyces cerevisiae Rot1p is an ER-localized membrane protein that may function with BiP/Kar2p in protein folding.Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins.Kar4p, a karyogamy-specific component of the yeast pheromone response pathway.SSI1 encodes a novel Hsp70 of the Saccharomyces cerevisiae endoplasmic reticulum.A novel Hsp70 of the yeast ER lumen is required for the efficient translocation of a number of protein precursorsAssembly of the ER to Golgi SNARE complex requires Uso1pBiP and Sec63p are required for both co- and posttranslational protein translocation into the yeast endoplasmic reticulum.Role of the mitochondrial DnaJ homolog Mdj1p as a chaperone for mitochondrially synthesized and imported proteins.A yeast DnaJ homologue, Scj1p, can function in the endoplasmic reticulum with BiP/Kar2p via a conserved domain that specifies interactions with Hsp70sA second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiaeRvs161p interacts with Fus2p to promote cell fusion in Saccharomyces cerevisiae.Sls1p stimulates Sec63p-mediated activation of Kar2p in a conformation-dependent manner in the yeast endoplasmic reticulum.KAR5 encodes a novel pheromone-inducible protein required for homotypic nuclear fusion.Regulation of 70-kDa heat-shock-protein ATPase activity and substrate binding by human DnaJ-like proteins, HSJ1a and HSJ1bBiP/Kar2p serves as a molecular chaperone during carboxypeptidase Y folding in yeastBiP clustering facilitates protein folding in the endoplasmic reticulumInteraction of the Hsp70 molecular chaperone, DnaK, with its cochaperone DnaJ.Approaches for probing the sequence space of substrates recognized by molecular chaperonesEssential role of calcineurin in response to endoplasmic reticulum stress.The J-domain proteins of Arabidopsis thaliana: an unexpectedly large and diverse family of chaperonesQuantifying the role of chaperones in protein translocation by computational modeling.Biology of the heat shock response and protein chaperones: budding yeast (Saccharomyces cerevisiae) as a model system.DNM1, a dynamin-related gene, participates in endosomal trafficking in yeast.Interaction between BiP and Sec63p is required for the completion of protein translocation into the ER of Saccharomyces cerevisiae.The lumenal domain of Sec63p stimulates the ATPase activity of BiP and mediates BiP recruitment to the translocon in Saccharomyces cerevisiaeER membrane protein complex required for nuclear fusionMutation of sec63 in zebrafish causes defects in myelinated axons and liver pathologySpecific molecular chaperone interactions and an ATP-dependent conformational change are required during posttranslational protein translocation into the yeast ER.The uterine expression of SEC63 gene is up-regulated at implantation sites in association with the decidualization during the early pregnancy in mice.
P2860
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P2860
Genetic interactions between KAR2 and SEC63, encoding eukaryotic homologues of DnaK and DnaJ in the endoplasmic reticulum.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Genetic interactions between K ...... in the endoplasmic reticulum.
@en
Genetic interactions between K ...... in the endoplasmic reticulum.
@nl
type
label
Genetic interactions between K ...... in the endoplasmic reticulum.
@en
Genetic interactions between K ...... in the endoplasmic reticulum.
@nl
prefLabel
Genetic interactions between K ...... in the endoplasmic reticulum.
@en
Genetic interactions between K ...... in the endoplasmic reticulum.
@nl
P2093
P2860
P356
P1476
Genetic interactions between K ...... in the endoplasmic reticulum.
@en
P2093
H H Okamura
M A Scidmore
P2860
P304
P356
10.1091/MBC.4.11.1145
P577
1993-11-01T00:00:00Z