TRAF4 is a critical molecule for Akt activation in lung cancer.
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The sweet trap in tumors: aerobic glycolysis and potential targets for therapyPosttranslational regulation of Akt in human cancerEupafolin Exhibits Potent Anti-Angiogenic and Antitumor Activity in Hepatocellular Carcinoma.PERK silence inhibits glioma cell growth under low glucose stress by blockage of p-AKT and subsequent HK2's mitochondria translocation.TRAF4 promotes the growth and invasion of colon cancer through the Wnt/β-catenin pathway.Cytoplasmic TRAF4 contributes to the activation of p70s6k signaling pathway in breast cancer.Leptin and insulin up-regulate miR-4443 to suppress NCOA1 and TRAF4, and decrease the invasiveness of human colon cancer cells.EZH2-mediated Puma gene repression regulates non-small cell lung cancer cell proliferation and cisplatin-induced apoptosis.Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity.Chrysin inhibited tumor glycolysis and induced apoptosis in hepatocellular carcinoma by targeting hexokinase-2.TRAF4 enhances oral squamous cell carcinoma cell growth, invasion and migration by Wnt-β-catenin signaling pathway.Upregulated expression of ILF2 in non-small cell lung cancer is associated with tumor cell proliferation and poor prognosis.Systemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue.TRAF4 promotes lung cancer aggressiveness by modulating tumor microenvironment in normal fibroblasts.The Glycolytic Switch in Tumors: How Many Players Are Involved?Deguelin, an Aurora B Kinase Inhibitor, Exhibits Potent Anti-Tumor Effect in Human Esophageal Squamous Cell Carcinoma.Oxymatrine inhibits non-small cell lung cancer via suppression of EGFR signaling pathway.Molecular basis for unique specificity of human TRAF4 for platelets GPIbβ and GPVI.TRAF6 regulates proliferation of stromal cells in the transition and peripheral zones of benign prostatic hyperplasia via Akt/mTOR signaling.Epstein-Barr virus encoded latent membrane protein 1 suppresses necroptosis through targeting RIPK1/3 ubiquitination.Computational trans-omics approach characterised methylomic and transcriptomic involvements and identified novel therapeutic targets for chemoresistance in gastrointestinal cancer stem cells.The F-box protein FBXL18 promotes glioma progression by promoting K63-linked ubiquitination of Akt.Deguelin suppresses angiogenesis in human hepatocellular carcinoma by targeting HGF-c-Met pathway.TRAF6 regulates EGF-induced cell transformation and cSCC malignant phenotype through CD147/EGFR.PIWIL3/OIP5-AS1/miR-367-3p/CEBPA feedback loop regulates the biological behavior of glioma cells.Krüppel-like factor 4 promotes c-Met amplification-mediated gefitinib resistance in non-small-cell lung cancer.TRAF4-mediated ubiquitination of NGF receptor TrkA regulates prostate cancer metastasis.Genetic Alterations of TRAF Proteins in Human CancersmiR-29s function as tumor suppressors in gliomas by targeting TRAF4 and predict patient prognosisMiR-29a Inhibits Glioma Tumorigenesis through a Negative Feedback Loop of TRAF4/Akt SignalingDeath receptor 6 promotes ovarian cancer cell migration through KIF11
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TRAF4 is a critical molecule for Akt activation in lung cancer.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 23 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
TRAF4 is a critical molecule for Akt activation in lung cancer.
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TRAF4 is a critical molecule for Akt activation in lung cancer.
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TRAF4 is a critical molecule for Akt activation in lung cancer.
@en
TRAF4 is a critical molecule for Akt activation in lung cancer.
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prefLabel
TRAF4 is a critical molecule for Akt activation in lung cancer.
@en
TRAF4 is a critical molecule for Akt activation in lung cancer.
@nl
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P2860
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TRAF4 is a critical molecule for Akt activation in lung cancer
@en
P2093
Ann M Bode
DoYoung Lim
Lanbo Xiao
Mee-Hyun Lee
P2860
P304
P356
10.1158/0008-5472.CAN-13-0913
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P50
P577
2013-10-23T00:00:00Z