Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferator-activated receptor-alpha - Wikidata - awgldk - TriplyDB

Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferator-activated receptor-alpha

Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferator-activated receptor-alpha

http://www.wikidata.org/entity/Q37376511

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Effect of alcohol on adipose tissue: a review on ethanol mediated adipose tissue injury Alcoholic and non-alcoholic steatohepatitis New advances in molecular mechanisms and emerging therapeutic targets in alcoholic liver diseases Alcoholic liver disease: pathogenesis and new therapeutic targets.Crosstalk of HNF4α with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipids CMZ reversed chronic ethanol-induced disturbance of PPAR-α possibly by suppressing oxidative stress and PGC-1α acetylation, and activating the MAPK and GSK3β pathway Zinc deficiency mediates alcohol-induced apoptotic cell death in the liver of rats through activating ER and mitochondrial cell death pathways Dynamic transcriptomic profiles of zebrafish gills in response to zinc depletion.Dynamic transcriptomic profiles of zebrafish gills in response to zinc supplementation.New therapeutic targets in alcoholic hepatitis.Dysregulation of hepatic zinc transporters in a mouse model of alcoholic liver disease The plausibility of maternal nutritional status being a contributing factor to the risk for fetal alcohol spectrum disorders: the potential influence of zinc status as an example.Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: role of signal transducer and activator of transcription 3.Alterations in hepatic mRNA expression of phase II enzymes and xenobiotic transporters after targeted disruption of hepatocyte nuclear factor 4 alpha Reduced susceptibility of DNA methyltransferase 1 hypomorphic (Dnmt1N/+) mice to hepatic steatosis upon feeding liquid alcohol diet.Hyperhomocysteinemia potentiates hyperglycemia-induced inflammatory monocyte differentiation and atherosclerosis.Chronic alcohol exposure disturbs lipid homeostasis at the adipose tissue-liver axis in mice: analysis of triacylglycerols using high-resolution mass spectrometry in combination with in vivo metabolite deuterium labeling Identification of novel clinical factors associated with hepatic fat accumulation in extreme obesity.Dietary zinc deficiency exaggerates ethanol-induced liver injury in mice: involvement of intrahepatic and extrahepatic factors Role of hypoxia inducing factor-1β in alcohol-induced autophagy, steatosis and liver injury in mice.Association of serum zinc levels with liver function and survival in patients awaiting liver transplantation.Activation of peroxisome proliferator-activated receptor-γ by rosiglitazone improves lipid homeostasis at the adipose tissue-liver axis in ethanol-fed mice.A multi-mineral natural product inhibits liver tumor formation in C57BL/6 mice.Elevated copper impairs hepatic nuclear receptor function in Wilson's disease.Preservation of hepatocyte nuclear factor-4α contributes to the beneficial effect of dietary medium chain triglyceride on alcohol-induced hepatic lipid dyshomeostasis in rats Carboxylesterase 1 Is Regulated by Hepatocyte Nuclear Factor 4α and Protects Against Alcohol- and MCD diet-induced Liver Injury.Status of essential trace minerals and oxidative stress in viral hepatitis C patients with nonalcoholic fatty liver disease A multimineral natural product from red marine algae reduces colon polyp formation in C57BL/6 mice.Systematic investigation of transcription factors critical in the protection against cerebral ischemia by Danhong injection.Defect of mitochondrial respiratory chain is a mechanism of ROS overproduction in a rat model of alcoholic liver disease: role of zinc deficiency.Chronic Moderate Alcohol Intakes Accelerate SR-B1 Mediated Reverse Cholesterol Transport.Deletion of angiotensin II type 1 receptor gene or scavenge of superoxide prevents chronic alcohol-induced aortic damage and remodelling Alcoholism causes alveolar macrophage zinc deficiency and immune dysfunction.Increased plasma corticosterone contributes to the development of alcoholic fatty liver in mice.Regulation of hepatic microRNA expression by hepatocyte nuclear factor 4 alpha.Zinc and alcoholic liver disease.Pharmaconutrition for the obese, critically ill patient.Zinc and liver disease.Zinc and autophagy.Binge ethanol-induced HDAC3 down-regulates Cpt1α expression leading to hepatic steatosis and injury.

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Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferator-activated receptor-alpha

http://www.wikidata.org/entity/Q37376511

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on October 2009

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

Zinc supplementation reverses ...... rator-activated receptor-alpha

@en

Zinc supplementation reverses ...... ator-activated receptor-alpha.

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type

label

Zinc supplementation reverses ...... rator-activated receptor-alpha

@en

Zinc supplementation reverses ...... ator-activated receptor-alpha.

@nl

prefLabel

Zinc supplementation reverses ...... rator-activated receptor-alpha

@en

Zinc supplementation reverses ...... ator-activated receptor-alpha.

@nl

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Zinc supplementation reverses ...... rator-activated receptor-alpha

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Craig J McClain

http://www.w3.org/2001/XMLSchema#string

Jie Liu

http://www.w3.org/2001/XMLSchema#string

Wei Zhong

http://www.w3.org/2001/XMLSchema#string

Xinqin Kang

http://www.w3.org/2001/XMLSchema#string

Y James Kang

http://www.w3.org/2001/XMLSchema#string

Zhanxiang Zhou

http://www.w3.org/2001/XMLSchema#string

Zhenyuan Song

http://www.w3.org/2001/XMLSchema#string

P2860

Control of pancreas and liver gene expression by HNF transcription factors

Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha)

Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

Changes in rat hepatic gene expression in response to zinc deficiency as assessed by DNA arrays.

Transcriptome and proteome analysis identifies the pathways that increase hepatic lipid accumulation in zinc-deficient rats.

The antioxidant properties of zinc.

Oxidation of zinc finger transcription factors: physiological consequences.

Oxidation of zinc-binding cysteine residues in transcription factor proteins.

Molecular mechanisms of alcoholic fatty liver: role of peroxisome proliferator-activated receptor alpha.

Zinc supplementation prevents alcoholic liver injury in mice through attenuation of oxidative stress.

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1241-1250

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scholarly article

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10.1002/HEP.23090

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4

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50

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2009-10-01T00:00:00Z

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26700184

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19637192

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2757527

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