about
Polyacetylenes from Notopterygium incisum--new selective partial agonists of peroxisome proliferator-activated receptor-gammaDiscovery and resupply of pharmacologically active plant-derived natural products: A reviewNatural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a reviewIdentification of isosilybin a from milk thistle seeds as an agonist of peroxisome proliferator-activated receptor gammaTaspine: bioactivity-guided isolation and molecular ligand-target insight of a potent acetylcholinesterase inhibitor from Magnolia x soulangianaComputer-aided discovery, validation, and mechanistic characterization of novel neolignan activators of peroxisome proliferator-activated receptor gammaHonokiol: a non-adipogenic PPARγ agonist from naturePharmacophore Models and Pharmacophore-Based Virtual Screening: Concepts and Applications Exemplified on Hydroxysteroid DehydrogenasesSelective inhibition of 11beta-hydroxysteroid dehydrogenase 1 by 18alpha-glycyrrhetinic acid but not 18beta-glycyrrhetinic acidThe anabolic androgenic steroid fluoxymesterone inhibits 11β-hydroxysteroid dehydrogenase 2-dependent glucocorticoid inactivationVirtual screening as a strategy for the identification of xenobiotics disrupting corticosteroid actionAccessing biological actions of Ganoderma secondary metabolites by in silico profilingMorphinans and isoquinolines: acetylcholinesterase inhibition, pharmacophore modeling, and interaction with opioid receptors.Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2.High-throughput structure-based pharmacophore modelling as a basis for successful parallel virtual screening.Discovery of nonsteroidal 17beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries.The Protein Data Bank (PDB), its related services and software tools as key components for in silico guided drug discovery.The UV-filter benzophenone-1 inhibits 17beta-hydroxysteroid dehydrogenase type 3: Virtual screening as a strategy to identify potential endocrine disrupting chemicals.Applications of integrated data mining methods to exploring natural product space for acetylcholinesterase inhibitors.Identification of bioactive natural products by pharmacophore-based virtual screening.Tetra- and pentacyclic triterpene acids from the ancient anti-inflammatory remedy frankincense as inhibitors of microsomal prostaglandin E(2) synthase-1Ligand-based pharmacophore modeling and virtual screening for the discovery of novel 17β-hydroxysteroid dehydrogenase 2 inhibitors.Pharmacophore-based discovery of FXR agonists. Part I: Model development and experimental validation.Identification of novel liver X receptor activators by structure-based modelingFormation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1.Identification of plumericin as a potent new inhibitor of the NF-κB pathway with anti-inflammatory activity in vitro and in vivoDiscovery of a novel IKK-β inhibitor by ligand-based virtual screening techniquesPharmacophore modeling and virtual screening for novel acidic inhibitors of microsomal prostaglandin E₂ synthase-1 (mPGES-1)Predicting cyclooxygenase inhibition by three-dimensional pharmacophoric profiling. Part II: Identification of enzyme inhibitors from Prasaplai, a Thai traditional medicineExperimentally validated HERG pharmacophore models as cardiotoxicity prediction tools.Methods for generating and applying pharmacophore models as virtual screening filters and for bioactivity profiling.Prospective performance evaluation of selected common virtual screening tools. Case study: Cyclooxygenase (COX) 1 and 2.Pharmacophore-based discovery of FXR-agonists. Part II: identification of bioactive triterpenes from Ganoderma lucidumDiscovery of novel, non-acidic mPGES-1 inhibitors by virtual screening with a multistep protocol.Pharmacophore-based discovery of a novel cytosolic phospholipase A(2)α inhibitor.Reprint of "In silico methods in the discovery of endocrine disrupting chemicals".Predicting Cyclooxygenase Inhibition by Three-Dimensional Pharmacophoric Profiling. Part I: Model Generation, Validation and Applicability in Ethnopharmacology.Pharmacophore Model Refinement for 11β-Hydroxysteroid Dehydrogenase Inhibitors: Search for Modulators of Intracellular Glucocorticoid Concentrations.Evaluation of selected 3D virtual screening tools for the prospective identification of peroxisome proliferator-activated receptor (PPAR) γ partial agonists.Why drugs fail--a study on side effects in new chemical entities.
P50
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Daniela Schuster
@ast
Daniela Schuster
@en
Daniela Schuster
@es
Daniela Schuster
@nl
Daniela Schuster
@sl
type
label
Daniela Schuster
@ast
Daniela Schuster
@en
Daniela Schuster
@es
Daniela Schuster
@nl
Daniela Schuster
@sl
prefLabel
Daniela Schuster
@ast
Daniela Schuster
@en
Daniela Schuster
@es
Daniela Schuster
@nl
Daniela Schuster
@sl
P1053
C-1024-2014
P106
P21
P2456
P2798
P31
P3829
P496
0000-0002-9933-8938