about
Novel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformationThe therapeutic implications of plasticity of the cancer stem cell phenotype.What does physics have to do with cancer?Allosteric inhibition enhances the efficacy of ABL kinase inhibitors to target unmutated BCR-ABL and BCR-ABL-T315IEffect of dedifferentiation on time to mutation acquisition in stem cell-driven cancers.Stochastic tunneling and metastable states during the somatic evolution of cancer.Evolution and phenotypic selection of cancer stem cellsCancer Stem Cells: A Minor Cancer Subpopulation that Redefines Global Cancer Features.Why doesn't imatinib cure chronic myeloid leukemia?Cancer stem cells: small subpopulation or evolving fraction?Extramedullary hematopoiesis (EMH) in laboratory animals: offering an insight into stem cell research.Cancer stem cells in human digestive tract malignancies.An Integrative multi-lineage model of variation in leukopoiesis and acute myelogenous leukemia.Dynamical models of mutated chronic myelogenous leukemia cells for a post-imatinib treatment scenario: Response to dasatinib or nilotinib therapy.Combined inhibition of β-catenin and Bcr-Abl synergistically targets tyrosine kinase inhibitor-resistant blast crisis chronic myeloid leukemia blasts and progenitors in vitro and in vivo.Mutations with epigenetic effects in myeloproliferative neoplasms and recent progress in treatment: Proceedings from the 5th International Post-ASH Symposium.Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer developmentStochastic dynamics of cancer initiation.Determining the role of inflammation in the selection of JAK2 mutant cells in myeloproliferative neoplasms.Leukemia stem cells.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 21 September 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A progenitor cell origin of myeloid malignancies
@en
A progenitor cell origin of myeloid malignancies.
@nl
type
label
A progenitor cell origin of myeloid malignancies
@en
A progenitor cell origin of myeloid malignancies.
@nl
prefLabel
A progenitor cell origin of myeloid malignancies
@en
A progenitor cell origin of myeloid malignancies.
@nl
P2093
P2860
P356
P1476
A progenitor cell origin of myeloid malignancies
@en
P2093
D Gary Gilliland
Franziska Michor
Hiroshi Haeno
Ross L Levine
P2860
P304
16616-16621
P356
10.1073/PNAS.0908107106
P407
P577
2009-09-21T00:00:00Z