Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci. - Wikidata - awgldk - TriplyDB

Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci.

Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci.

http://www.wikidata.org/entity/Q37377456

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Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2 Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signalling Transcriptional control of innate lymphoid cells Factors and networks that underpin early hematopoiesis The establishment of B versus T cell identity Cyclic AMP signaling inhibits megakaryocytic differentiation by targeting transcription factor 3 (E2A) cyclin-dependent kinase inhibitor 1A (CDKN1A) transcriptional axis.From hematopoietic progenitors to B cells: mechanisms of lineage restriction and commitment A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate.Epigenetic control of recombination in the immune system Aryl hydrocarbon receptor promotes RORγt⁺ group 3 ILCs and controls intestinal immunity and inflammation.The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor.Replication-coupled chromatin assembly generates a neuronal bilateral asymmetry in C. elegans Biochemical and phosphoproteomic analysis of the helix-loop-helix protein E47.Histone reader BRWD1 targets and restricts recombination to the Igk locus.Biased Immunoglobulin Light Chain Gene Usage in the Shark.The transcription factor Lyl-1 regulates lymphoid specification and the maintenance of early T lineage progenitors.New roles for DNA cytosine modification, eRNA, anchors, and superanchors in developing B cell progenitors.The balance of Id3 and E47 determines neural stem/precursor cell differentiation into astrocytes Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics.Notch-regulated periphery B cell differentiation involves suppression of E protein function.A recurrent dominant negative E47 mutation causes agammaglobulinemia and BCR(-) B cells.Oncogenic mechanisms in Burkitt lymphoma Balancing Proliferation with Igκ Recombination during B-lymphopoiesis Allelic exclusion of immunoglobulin genes: models and mechanisms.Complementary regulation of early B-lymphoid differentiation by genetic and epigenetic mechanisms.The regulatory network of B-cell differentiation: a focused view of early B-cell factor 1 function The opposing roles of the transcription factor E2A and its antagonist Id3 that orchestrate and enforce the naive fate of T cells.Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic progenitors.Signaling proteins and transcription factors in normal and malignant early B cell development.Mechanisms of central tolerance for B cells.Relevance of ID3-TCF3-CCND3 pathway mutations in pediatric aggressive B-cell lymphoma treated according to the non-Hodgkin Lymphoma Berlin-Frankfurt-Münster protocols.Isoform-Specific Expression and Feedback Regulation of E Protein TCF4 Control Dendritic Cell Lineage Specification.Id3 Orchestrates Germinal Center B Cell Development.Evidence for Ig Light Chain Isotype Exclusion in Shark B Lymphocytes Suggests Ordered Mechanisms.Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells.The E2A splice variant E47 regulates the differentiation of projection neurons via p57(KIP2) during cortical development.Mycobacteria exploit nitric oxide-induced transformation of macrophages into permissive giant cells.Checkpoints of B cell differentiation: visualizing Ig-centric processes.Epigenetic silencing of miR-125b is required for normal B-cell development.BRWD1 orchestrates epigenetic landscape of late B lymphopoiesis

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Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci.

http://www.wikidata.org/entity/Q37377456

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 14 September 2009

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

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name

Distinct roles for E12 and E47 ...... munoglobulin light chain loci.

@en

Distinct roles for E12 and E47 ...... munoglobulin light chain loci.

@nl

type

label

Distinct roles for E12 and E47 ...... munoglobulin light chain loci.

@en

Distinct roles for E12 and E47 ...... munoglobulin light chain loci.

@nl

prefLabel

Distinct roles for E12 and E47 ...... munoglobulin light chain loci.

@en

Distinct roles for E12 and E47 ...... munoglobulin light chain loci.

@nl

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Journal of Experimental Medicine

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Distinct roles for E12 and E47 ...... munoglobulin light chain loci.

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Cornelis Murre

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David Nemazee

http://www.w3.org/2001/XMLSchema#string

Kristina Beck

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Mandy M Peak

http://www.w3.org/2001/XMLSchema#string

Takayuki Ota

http://www.w3.org/2001/XMLSchema#string

P2860

Helix-loop-helix transcriptional activators bind to a sequence in glucocorticoid response elements of retrovirus enhancers

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

E2A and IRF-4/Pip promote chromatin modification and transcription of the immunoglobulin kappa locus in pre-B cells.

Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotent

Distinct promoters mediate the regulation of Ebf1 gene expression by interleukin-7 and Pax5

The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2

RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

The helix-loop-helix gene E2A is required for B cell formation

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

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2271-2284

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scholarly article

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10.1084/JEM.20090756

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P433

10

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206

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2009-09-14T00:00:00Z

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26810185

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19752184

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2757879

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