Characterization of Mycobacterium leprae RecA intein, a LAGLIDADG homing endonuclease, reveals a unique mode of DNA binding, helical distortion, and cleavage compared with a canonical LAGLIDADG homing endonuclease
about
A group II intron encodes a functional LAGLIDADG homing endonuclease and self-splices under moderate temperature and ionic conditions.Mutational analysis of active-site residues in the Mycobacterium leprae RecA intein, a LAGLIDADG homing endonuclease: Asp(122) and Asp(193) are crucial to the double-stranded DNA cleavage activity whereas Asp(218) is not.
P2860
Characterization of Mycobacterium leprae RecA intein, a LAGLIDADG homing endonuclease, reveals a unique mode of DNA binding, helical distortion, and cleavage compared with a canonical LAGLIDADG homing endonuclease
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Characterization of Mycobacter ...... LAGLIDADG homing endonuclease
@en
Characterization of Mycobacter ...... LAGLIDADG homing endonuclease.
@nl
type
label
Characterization of Mycobacter ...... LAGLIDADG homing endonuclease
@en
Characterization of Mycobacter ...... LAGLIDADG homing endonuclease.
@nl
prefLabel
Characterization of Mycobacter ...... LAGLIDADG homing endonuclease
@en
Characterization of Mycobacter ...... LAGLIDADG homing endonuclease.
@nl
P2093
P2860
P356
P1476
Characterization of Mycobacter ...... LAGLIDADG homing endonuclease
@en
P2093
Alfred Pingoud
George H Silva
K Muniyappa
Pankaj Tripathi
Pawan Singh
P2860
P304
25912-25928
P356
10.1074/JBC.M109.042861
P407
P577
2009-07-15T00:00:00Z