Chronic late-gestation hypoglycemia upregulates hepatic PEPCK associated with increased PGC1alpha mRNA and phosphorylated CREB in fetal sheep.
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Hepatitis C virus infection promotes hepatic gluconeogenesis through an NS5A-mediated, FoxO1-dependent pathway.Molecular mechanism of hepatitis C virus-induced glucose metabolic disordersImpact of embryo number and maternal undernutrition around the time of conception on insulin signaling and gluconeogenic factors and microRNAs in the liver of fetal sheepIntrauterine growth restriction and differential patterns of hepatic growth and expression of IGF1, PCK2, and HSDL1 mRNA in the sheep fetus in late gestation.Coordinated changes in hepatic amino acid metabolism and endocrine signals support hepatic glucose production during fetal hypoglycemiaCatecholamines mediate multiple fetal adaptations during placental insufficiency that contribute to intrauterine growth restriction: lessons from hyperthermic sheep.The intrauterine growth restriction phenotype: fetal adaptations and potential implications for later life insulin resistance and diabetes.Moderate global reduction in maternal nutrition has differential stage of gestation specific effects on {beta}1- and {beta}2-adrenergic receptors in the fetal baboon liver.A physiological increase in insulin suppresses gluconeogenic gene activation in fetal sheep with sustained hypoglycemia.Increased hepatic glucose production in fetal sheep with intrauterine growth restriction is not suppressed by insulin.Consequences of a compromised intrauterine environment on islet function.Impact of maternal undernutrition around the time of conception on factors regulating hepatic lipid metabolism and microRNAs in singleton and twin fetusesIncreased fetal insulin concentrations for one week fail to improve insulin secretion or β-cell mass in fetal sheep with chronically reduced glucose supplyIncreased amino acid supply potentiates glucose-stimulated insulin secretion but does not increase β-cell mass in fetal sheep.Chronic anemic hypoxemia increases plasma glucagon and hepatic PCK1 mRNA in late-gestation fetal sheep.Effects of chronic hypoglycemia and euglycemic correction on lysine metabolism in fetal sheepIntrauterine growth restriction increases fetal hepatic gluconeogenic capacity and reduces messenger ribonucleic acid translation initiation and nutrient sensing in fetal liver and skeletal muscleProlonged maternal amino acid infusion in late-gestation pregnant sheep increases fetal amino acid oxidation.Maternal obesity accelerates fetal pancreatic beta-cell but not alpha-cell development in sheep: prenatal consequences.Effects of maternal global nutrient restriction on fetal baboon hepatic insulin-like growth factor system genes and gene products.Knowledge gaps and research needs for understanding and treating neonatal hypoglycemia: workshop report from Eunice Kennedy Shriver National Institute of Child Health and Human Development.Role of placental insufficiency and intrauterine growth restriction on the activation of fetal hepatic glucose production.DNA methylation patterns and gene expression associated with litter size in Berkshire pig placentaHepatitis C virus NS5A protein enhances gluconeogenesis through upregulation of Akt-/JNK-PEPCK signalling pathways.Epigenetic modification of fetal baboon hepatic phosphoenolpyruvate carboxykinase following exposure to moderately reduced nutrient availability.Remembering development - epigenetic responses to fetal malnutrition.Impact of maternal overnutrition on gluconeogenic factors and methylation of the phosphoenolpyruvate carboxykinase promoter in the fetal and postnatal liver.
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Chronic late-gestation hypoglycemia upregulates hepatic PEPCK associated with increased PGC1alpha mRNA and phosphorylated CREB in fetal sheep.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 04 December 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Chronic late-gestation hypogly ...... horylated CREB in fetal sheep.
@en
Chronic late-gestation hypogly ...... horylated CREB in fetal sheep.
@nl
type
label
Chronic late-gestation hypogly ...... horylated CREB in fetal sheep.
@en
Chronic late-gestation hypogly ...... horylated CREB in fetal sheep.
@nl
prefLabel
Chronic late-gestation hypogly ...... horylated CREB in fetal sheep.
@en
Chronic late-gestation hypogly ...... horylated CREB in fetal sheep.
@nl
P2093
P2860
P1476
Chronic late-gestation hypogly ...... phorylated CREB in fetal sheep
@en
P2093
Dan LoTurco
Jacob E Friedman
James S Barry
Laura D Brown
Paul J Rozance
Stephanie R Thorn
Timothy R H Regnault
William W Hay
P2860
P304
P356
10.1152/AJPENDO.00639.2007
P50
P577
2007-12-04T00:00:00Z