about
In type 1 diabetes a subset of anti-coxsackievirus B4 antibodies recognize autoantigens and induce apoptosis of pancreatic beta cellsStructure and function of TMEM16 proteins (anoctamins)Thiocyanate transport in resting and IL-4-stimulated human bronchial epithelial cells: role of pendrin and anion channelsSmall molecule correctors of F508del-CFTR discovered by structure-based virtual screeningAntihypertensive 1,4-dihydropyridines as correctors of the cystic fibrosis transmembrane conductance regulator channel gating defect caused by cystic fibrosis mutations.High-throughput screening of libraries of compounds to identify CFTR modulators.Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening.Rescue of the mutant CFTR chloride channel by pharmacological correctors and low temperature analyzed by gene expression profiling.Pharmacological Correctors of Mutant CFTR Mistrafficking.Dual activity of aminoarylthiazoles on the trafficking and gating defects of the cystic fibrosis transmembrane conductance regulator chloride channel caused by cystic fibrosis mutations.Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis.Development of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice.Genetic Inhibition Of The Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated To F508del Cystic Fibrosis Mutation.Effect of inflammatory stimuli on airway ion transport.Mutation-specific potency and efficacy of cystic fibrosis transmembrane conductance regulator chloride channel potentiators.Phenylhydrazones as Correctors of a Mutant Cystic Fibrosis Transmembrane Conductance Regulator.Novel Hits in the Correction of ΔF508-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein: Synthesis, Pharmacological, and ADME Evaluation of Tetrahydropyrido[4,3-d]pyrimidines for the Potential Treatment of Cystic Fibrosis.RNF5, DAB2 and Friends: Novel Drug Targets for Cystic Fibrosis.The search for a common structural moiety among selected pharmacological correctors of the mutant CFTR chloride channel.Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia.Asymmetric 4-aryl-1,4-dihydropyridines potentiate mutant cystic fibrosis transmembrane conductance regulator (CFTR).Cystic fibrosis: a new target for 4-Imidazo[2,1-b]thiazole-1,4-dihydropyridines.Synthesis of 4-thiophen-2'-yl-1,4-dihydropyridines as potentiators of the CFTR chloride channel.Rational design of a nonpeptide general chemical scaffold for reversible inhibition of PDZ domain interactions.Evidence against the rescue of defective DeltaF508-CFTR cellular processing by curcumin in cell culture and mouse models.Block of CFTR-dependent chloride currents by inhibitors of multidrug resistance-associated proteins.Nanomolar affinity small molecule correctors of defective Delta F508-CFTR chloride channel gating.Synthesis and biological evaluation of novel thiazole- VX-809 hybrid derivatives as F508del correctors by QSAR-based filtering tools.High-throughput screening identifies FAU protein as a regulator of mutant cystic fibrosis transmembrane conductance regulator channel.Therapeutic approaches to CFTR dysfunction: From discovery to drug development.In vitro recapitulation of the site-specific editing (to wild-type) of mutant IDS mRNA transcripts, and the characterization of IDS protein translated from the edited mRNAs.Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia.Epithelial sodium channel inhibition in primary human bronchial epithelia by transfected siRNA.Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway EpitheliaProteomic analysis of the airway surface liquid: modulation by proinflammatory cytokinesGelsolin Secretion in Interleukin-4–treated Bronchial Epithelia and in Asthmatic AirwaysChemically modified hCFTR mRNAs recuperate lung function in a mouse model of cystic fibrosisLigand-based design, in silico ADME-Tox filtering, synthesis and biological evaluation to discover new soluble 1,4-DHP-based CFTR activatorsThymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epitheliaHigh-Content Screening Identifies Vanilloids as a Novel Class of Inhibitors of NET Formation
P50
Q21133650-4CD4B479-B1C7-475B-8B80-B5279F38CBF9Q26851981-4B20C068-4CC7-428A-9C3C-5CADEDF1C23DQ28296176-0FB08AD2-A3F5-40F3-9C1F-F649E85B5A18Q30577535-17844A58-61AE-4D58-A486-0204FFAAFAEAQ33223017-DBA89FD9-43E4-4F64-ACAC-E7B5518ED272Q33905490-450B5146-C9D4-4514-84FF-1F7884940708Q33925348-00E05707-F2D1-420C-92C1-5279548D91D3Q33960117-E7F5F670-023D-47B9-93CA-25351B7D4160Q34444239-6ECF27A3-A2B7-499D-AF0D-91BDAA78FFB0Q34869004-7E6A5EE5-3444-4195-A537-4AEDB503502AQ35652241-396C99EF-8858-4513-84FC-439C91C13190Q35661454-DB27D53E-1EBC-4F54-B53F-0B20FA8F94A6Q35693982-8743AAD0-7679-43E9-A8BF-4244E8EB1BEFQ36236767-BA424DA3-D405-4FBB-ABBC-07A6B7B29177Q37312856-EFB67F9D-1163-4D6D-8BFB-0FDEAEE2ABF6Q38809280-424555B7-4675-41F1-B423-27B15DD88739Q38820019-89DAC5A0-673B-487F-80CF-9A4DD851D327Q38975786-5C847068-758E-4402-9010-91BA829BF66BQ39077956-87EBF931-AED4-453E-A880-2D8DCF2E7A8AQ39276470-4AEDCA27-7D4E-4BBE-8C1D-CA776D7706A3Q39289881-2C38E26B-D498-48F3-8D80-F8C154FFC7B5Q39543517-60423382-5FA5-490B-A567-5CD3C73E2C81Q39780835-A843B949-6802-4E1A-B270-E3FE8F76A5E7Q40217311-58DF637D-CD25-4DAE-B2FE-5865EE0CC044Q40530907-A2C04B26-FE7D-42F7-87B4-A33B039238EFQ43116184-3A73B213-06EA-4A55-AA8A-434BD2F00D19Q44495355-EF0996B1-C8EE-4363-8671-78746F023DFEQ47260236-9A4FACF6-938B-4C5B-B59A-B8D327E8EB2CQ47381637-BC66F845-2E07-4EA7-8FD7-2460B6CA6F0DQ47794104-DA00587F-39FB-4805-B664-B2DD543DAAA0Q48182613-3A99E65D-B168-4419-8268-15087962085BQ50130517-D7485A0E-C809-42F4-8E94-D93433048B1AQ52588837-7FE732DA-2CDC-495E-A7BE-4CA08ADFE7C4Q56363938-73CA9AA2-D47D-4A67-B0EB-553A767D63C5Q58620322-C1F4327A-29E9-4DBB-933A-384E4EC03305Q58620329-E317F64D-EAAC-4895-BAC9-9867FBCF5A62Q59329077-87A63353-6C46-47B2-AEF0-204B24834A98Q60435092-C092395C-80C0-4285-8C41-5B196B3EC1B2Q64076934-D8FBDF58-8944-4E48-A7CD-A6E2374F169DQ64078728-412E23E6-0F33-4E18-90D6-D1C7284CD81E
P50
description
hulumtuese
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onderzoeker
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ricercatrice
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հետազոտող
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name
Nicoletta Pedemonte
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Nicoletta Pedemonte
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Nicoletta Pedemonte
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Nicoletta Pedemonte
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Nicoletta Pedemonte
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Nicoletta Pedemonte
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type
label
Nicoletta Pedemonte
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Nicoletta Pedemonte
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Nicoletta Pedemonte
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Nicoletta Pedemonte
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Nicoletta Pedemonte
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Nicoletta Pedemonte
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prefLabel
Nicoletta Pedemonte
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Nicoletta Pedemonte
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Nicoletta Pedemonte
@es
Nicoletta Pedemonte
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Nicoletta Pedemonte
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Nicoletta Pedemonte
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P214
P1053
B-3607-2010
P106
P21
P214
P31
P3829
P396
IT\ICCU\CFIV\249929
P496
0000-0002-5161-1720
P7859
viaf-307335867