about
Novel triazine JPC-2067-B inhibits Toxoplasma gondii in vitro and in vivoRotating with the brakes on and other unresolved features of the vacuolar ATPaseReplace, reuse, recycle: improving the sustainable use of phosphorus by plantsFlexibility within the rotor and stators of the vacuolar H+-ATPaseT. gondii RP promoters & knockdown reveal molecular pathways associated with proliferation and cell-cycle arrestStudies ofToxoplasma gondiiandPlasmodium falciparumenoyl acyl carrier protein reductase and implications for the development of antiparasitic agentsType I and type II fatty acid biosynthesis in Eimeria tenella: enoyl reductase activity and structureIdentification and Development of Novel Inhibitors of Toxoplasma gondii Enoyl ReductaseThe benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme targetCryo-electron microscopy of the vacuolar ATPase motor reveals its mechanical and regulatory complexityThe use of SMALPs as a novel membrane protein scaffold for structure study by negative stain electron microscopy.The changing landscape of membrane protein structural biology through developments in electron microscopy.The essential GTPase YphC displays a major domain rearrangement associated with nucleotide binding.Delivery of antimicrobials into parasitesSubunit positioning and stator filament stiffness in regulation and power transmission in the V1 motor of the Manduca sexta V-ATPase.In situ formation of magnetopolymersomes via electroporation for MRI.Methods to account for movement and flexibility in cryo-EM data processing.Corrigendum to 'Methods to account for movement and flexibility in cryo-EM data processing' [Methods 100 (2016) 35-41].Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I.PA1b inhibitor binding to subunits c and e of the vacuolar ATPase reveals its insecticidal mechanismMaternal inheritance and stage-specific variation of the apicoplast in Toxoplasma gondii during development in the intermediate and definitive host.ALOX12 in human toxoplasmosis.Identification of T. gondii epitopes, adjuvants, and host genetic factors that influence protection of mice and humans.Non-synonymous single nucleotide polymorphisms in the P2X receptor genes: association with diseases, impact on receptor functions and potential use as diagnosis biomarkersNovel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.Mechanism of inhibition of mouse Slo3 (KCa 5.1) potassium channels by quinine, quinidine and bariumStructure-based identification and characterisation of structurally novel human P2X7 receptor antagonistsExpression, purification and preliminary crystallographic analysis of the Toxoplasma gondii enoyl reductase.An introduction to sample preparation and imaging by cryo-electron microscopy for structural biology.New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections.Modification of triclosan scaffold in search of improved inhibitors for enoyl-acyl carrier protein (ACP) reductase in Toxoplasma gondii.Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay.Spiroindolone that inhibits PfATPase4 is a potent, cidal inhibitor of Toxoplasma gondii tachyzoites in vitro and in vivoStructural divergence of the rotary ATPases.Extracellular and Luminal pH Regulation by Vacuolar H+-ATPase Isoform Expression and Targeting to the Plasma Membrane and Endosomes.Pi sensing and signalling: from prokaryotic to eukaryotic cells.The varied functions of aluminium-activated malate transporters-much more than aluminium resistance.Artificial membranes for membrane protein purification, functionality and structure studies.The conservation of phosphate-binding residues among PHT1 transporters suggests that distinct transport affinities are unlikely to result from differences in the phosphate-binding site.Durable vesicles for reconstitution of membrane proteins in biotechnology
P50
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P50
description
hulumtues
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Stephen Muench
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Stephen Muench
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Stephen Muench
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Stephen Muench
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Stephen Muench
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Stephen Muench
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Stephen Muench
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Stephen Muench
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Stephen Muench
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Stephen P Muench
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Stephen P Muench
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Stephen Muench
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Stephen Muench
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Stephen Muench
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P106
P1153
6603017352
P2031
1990-01-01T00:00:00Z
P21
P2798
P31
P496
0000-0001-6869-4414