Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chain.
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Microarray profiling of lymphocytes in internal diseases with an altered immune response: potential and methodologyThe Emerging and Diverse Roles of Src-Like Adaptor Proteins in Health and DiseaseSmall molecules in the treatment of systemic lupus erythematosusSLAMF6-driven co-stimulation of human peripheral T cells is defective in SLE T cellsReduced T-cell receptor CD3zeta-chain protein and sustained CD3epsilon expression at the site of mycobacterial infectionGenome scan of human systemic lupus erythematosus: evidence for linkage on chromosome 1q in African-American pedigreesCD3Z hypermethylation is associated with severe clinical manifestations in systemic lupus erythematosus and reduces CD3ζ-chain expression in T cells.The pathology of T cells in systemic lupus erythematosusMitochondrial hyperpolarization: a checkpoint of T-cell life, death and autoimmunity.T cell CD3ζ deficiency enables multiorgan tissue inflammation.Human immunodeficiency virus-specific circulating CD8 T lymphocytes have down-modulated CD3zeta and CD28, key signaling molecules for T-cell activation.The IL-2 defect in systemic lupus erythematosus disease has an expansive effect on host immunityCentral role of nitric oxide in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus.Lupus susceptibility genes on human chromosome 1.T cells as therapeutic targets in SLE.Protein phosphatase 2A is a negative regulator of IL-2 production in patients with systemic lupus erythematosus.Transcriptional activation of the human inducible nitric-oxide synthase promoter by Kruppel-like factor 6.Expression feature of CD3, FcεRIγ, and Zap-70 in patients with chronic lymphocytic leukemia.Splicing factor SF2/ASF rescues IL-2 production in T cells from systemic lupus erythematosus patients by activating IL-2 transcription.Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-gamma gene and protein expression in lupus T cellsFrom T to B and back again: positive feedback in systemic autoimmune disease.T lymphocytes from chagasic patients are activated but lack proliferative capacity and down-regulate CD28 and CD3ζ.Neutrophils with myeloid derived suppressor function deplete arginine and constrain T cell function in septic shock patients.Abnormal T cell signal transduction in systemic lupus erythematosus.Spleen tyrosine kinase (Syk) regulates systemic lupus erythematosus (SLE) T cell signaling.Abnormalities of T cell signaling in systemic lupus erythematosus.Immunopathology and the gene therapy of lupus.The role of nitric oxide in abnormal T cell signal transduction in systemic lupus erythematosusSystemic lupus erythematosus: from genes to organ damage.Targeting lymphocyte signaling pathways as a therapeutic approach to systemic lupus erythematosus.Genetic association of CD247 (CD3ζ) with SLE in a large-scale multiethnic study.T cells as a therapeutic target in SLE.Decreased expression of the CD3zeta chain in T cells infiltrating the synovial membrane of patients with osteoarthritis.Tissue-specific expression of human calcineurin-binding protein 1 in mouse synovial tissue can suppress inflammatory arthritis.Serine Arginine-Rich Splicing Factor 1 (SRSF1) Contributes to the Transcriptional Activation of CD3ζ in Human T Cells.Dissecting the molecular mechanisms of TCR zeta chain downregulation and T cell signaling abnormalities in human systemic lupus erythematosus.Altered signaling triggered by ligation of the TCR/CD3 receptor in T lymphocytes from patients with systemic lupus erythematosus: the road from anergy to autoimmunity.Mitochondrial dysfunction in T cells of patients with systemic lupus erythematosus.Decreased T cell ERK pathway signaling may contribute to the development of lupus through effects on DNA methylation and gene expression.Targeting CD40L: a promising therapeutic approach.
P2860
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P2860
Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chain.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 1998
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Altered pattern of TCR/CD3-med ...... he T cell receptor zeta chain.
@en
Altered pattern of TCR/CD3-med ...... he T cell receptor zeta chain.
@nl
type
label
Altered pattern of TCR/CD3-med ...... he T cell receptor zeta chain.
@en
Altered pattern of TCR/CD3-med ...... he T cell receptor zeta chain.
@nl
prefLabel
Altered pattern of TCR/CD3-med ...... he T cell receptor zeta chain.
@en
Altered pattern of TCR/CD3-med ...... he T cell receptor zeta chain.
@nl
P2093
P2860
P356
P1476
Altered pattern of TCR/CD3-med ...... he T cell receptor zeta chain.
@en
P2093
P2860
P304
P356
10.1172/JCI1457
P407
P577
1998-04-01T00:00:00Z