Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4.
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Update on CD40 and CD154 blockade in transplant modelsAdipose tissue-derived mesenchymal stem cells increase skin allograft survival and inhibit Th-17 immune responseElevated levels of interferon-γ production by memory T cells do not promote transplant tolerance resistance in aged recipientsCentral memory CD8+ T lymphocytes mediate lung allograft acceptance.Laminins affect T cell trafficking and allograft fate.Manipulating IL-2 availability amid presentation of donor MHC antigens suppresses murine alloimmune responses by inducing regulatory T cells.Immunization with host-type CD8{alpha}+ dendritic cells reduces experimental acute GVHD in an IL-10-dependent manner.The effects of tolerance on allograft damage caused by the innate immune systemVirus-induced abrogation of transplantation tolerance induced by donor-specific transfusion and anti-CD154 antibody.Fragile TIM-4-expressing tissue resident macrophages are migratory and immunoregulatory.Requirements for induction and maintenance of peripheral tolerance in stringent allograft modelsIncreased apoptosis of immunoreactive host cells and augmented donor leukocyte chimerism, not sustained inhibition of B7 molecule expression are associated with prolonged cardiac allograft survival in mice preconditioned with immature donor dendritiExogenous IFN-gamma ex vivo shapes the alloreactive T-cell repertoire by inhibition of Th17 responses and generation of functional Foxp3+ regulatory T cellsCD154 blockade alters innate immune cell recruitment and programs alloreactive CD8+ T cells into KLRG-1(high) short-lived effector T cells.Requirement for natural killer T (NKT) cells in the induction of allograft toleranceReprogramming the immune system.Costimulation couture: a designer approach to regulating autoimmunity.IL-6 induced by Staphylococcus aureus infection prevents the induction of skin allograft acceptance in mice.IFN-γ production by memory helper T cells is required for CD40-independent alloantibody responses.Induction of transplantation tolerance in non-human primate preclinical modelsA rational design approach for developing immunomodulators based on CD4 and CD8.An age-specific CD8+ T cell pathway that impairs the effectiveness of strategies to prolong allograft survivalIslet allograft tolerance in the absence of invariant natural killer T cellsRapid quantification of naive alloreactive T cells by TNF-alpha production and correlation with allograft rejection in mice.Antigen-specific induced Foxp3+ regulatory T cells are generated following CD40/CD154 blockade.Hematopoietic chimerism and central tolerance created by peripheral-tolerance induction without myeloablative conditioning.Dipeptidyl peptidase IV (DPPIV/CD26) inhibition does not improve engraftment of unfractionated syngeneic or allogeneic bone marrow after nonmyeloablative conditioningT-cell activation and transplantation tolerance.CD8(+)IL-17(+) T Cells Mediate Neutrophilic Airway Obliteration in T-bet-Deficient Mouse Lung Allograft Recipients.The role of coinhibitory signaling pathways in transplantation and toleranceAllograft rejection is restrained by short-lived TIM-3+PD-1+Foxp3+ Tregs.Intra-Bone Marrow Transplantation of Endosteal Bone Marrow Cells Facilitates Allogeneic Hematopoietic and Stromal Cells Engraftment Dependent on Early Expression of CXCL-12.Combined donor specific transfusion and anti-CD154 therapy achieves airway allograft tolerance.Homeostatic T cell proliferation as a barrier to T cell tolerance.Absence of MyD88 signaling induces donor-specific kidney allograft toleranceCD40/CD154 blockade inhibits dendritic cell expression of inflammatory cytokines but not costimulatory moleculesCoinhibitory T-cell signaling in islet allograft rejection and tolerance.Viral infection: a potent barrier to transplantation tolerance.A critical precursor frequency of donor-reactive CD4+ T cell help is required for CD8+ T cell-mediated CD28/CD154-independent rejection.Idd loci synergize to prolong islet allograft survival induced by costimulation blockade in NOD mice
P2860
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P2860
Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 1998
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Long-term survival of skin all ...... , interferon-gamma, and CTLA4.
@en
Long-term survival of skin all ...... , interferon-gamma, and CTLA4.
@nl
type
label
Long-term survival of skin all ...... , interferon-gamma, and CTLA4.
@en
Long-term survival of skin all ...... , interferon-gamma, and CTLA4.
@nl
prefLabel
Long-term survival of skin all ...... , interferon-gamma, and CTLA4.
@en
Long-term survival of skin all ...... , interferon-gamma, and CTLA4.
@nl
P2093
P2860
P356
P1476
Long-term survival of skin all ...... , interferon-gamma, and CTLA4.
@en
P2093
A A Rossini
D L Greiner
E J Gordon
J P Mordes
L D Shultz
N E Phillips
R J Noelle
T G Markees
P2860
P304
P356
10.1172/JCI2703
P407
P577
1998-06-01T00:00:00Z