Interaction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases.
about
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separaseHuman CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phaseThe Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeastPhosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localizationIdentification and characterization of Saccharomyces cerevisiae Cdc6 DNA-binding propertiesAssembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinaseBinding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycleATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA.Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6The B2 element of the Saccharomyces cerevisiae ARS1 origin of replication requires specific sequences to facilitate pre-RC formationThe Hect domain E3 ligase Tom1 and the F-box protein Dia2 control Cdc6 degradation in G1 phaseCLB5 and CLB6 are required for premeiotic DNA replication and activation of the meiotic S/M checkpoint.The essential role of Saccharomyces cerevisiae CDC6 nucleotide-binding site in cell growth, DNA synthesis, and Orc1 association.Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast.Cyclin-dependent kinases prevent DNA re-replication through multiple mechanismsSeparate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis.Identification of Cdc6 protein domains involved in interaction with Mcm2 protein and Cdc4 protein in budding yeast cellsThe Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cellsPersistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutantsMcm2 is a target of regulation by Cdc7-Dbf4 during the initiation of DNA synthesis.A comprehensive molecular interaction map of the budding yeast cell cycle.Targeted destruction of DNA replication protein Cdc6 by cell death pathways in mammals and yeast.Identification of the sequence responsible for the nuclear localization of human Cdc6.Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae.Cdc6 cooperates with Sic1 and Hct1 to inactivate mitotic cyclin-dependent kinases.Synthesis and turn-over of the replicative Cdc6 protein during the HeLa cell cycle.Cdc6 ATPase activity regulates ORC x Cdc6 stability and the selection of specific DNA sequences as origins of DNA replication.Mutation of cyclin/cdk phosphorylation sites in HsCdc6 disrupts a late step in initiation of DNA replication in human cellsOrigin licensing and programmed cell death: a hypothesis.The Cdc6p nucleotide-binding motif is required for loading mcm proteins onto chromatin.Regulation of the final stage of mitosis by components of the pre-replicative complex and a polo kinase.Genetic and biochemical evaluation of the importance of Cdc6 in regulating mitotic exitEukaryotic MCM proteins: beyond replication initiation.Roles of the CDK phosphorylation sites of yeast Cdc6 in chromatin binding and rereplication.Stepwise assembly of initiation proteins at budding yeast replication origins in vitro.Prediction of cyclin-dependent kinase phosphorylation substrates.Ectopic induction of Clb2 in early G1 phase is sufficient to block prereplicative complex formation in Saccharomyces cerevisiae.Interaction of the S phase regulator cdc18 with cyclin-dependent kinase in fission yeast.Chemical visualization of phosphoproteomes on membrane.The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation.
P2860
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P2860
Interaction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Interaction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases.
@en
Interaction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases.
@nl
type
label
Interaction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases.
@en
Interaction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases.
@nl
prefLabel
Interaction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases.
@en
Interaction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases.
@nl
P2093
P2860
P356
P1476
Interaction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases.
@en
P2093
P2860
P304
P356
10.1091/MBC.7.11.1723
P577
1996-11-01T00:00:00Z