Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy. - Wikidata - awgldk - TriplyDB

Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy.

Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy.

http://www.wikidata.org/entity/Q37384434

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APC-derived cytokines and T cell polarization in autoimmune inflammation Role of immunosuppressive therapy for the treatment of multiple sclerosis Treatment of multiple sclerosis with cyclophosphamide: critical review of clinical and immunologic effects IL-23: changing the verdict on IL-12 function in inflammation and autoimmunity Cladribine Exposure Results in a Sustained Modulation of the Cytokine Response in Human Peripheral Blood Mononuclear Cells Deficiency in regulatory T cells results in development of antimitochondrial antibodies and autoimmune cholangitis.The safety profile of cyclophosphamide in multiple sclerosis therapy.Th17 cells in autoimmune demyelinating disease.Astragalosides from Radix Astragali benefits experimental autoimmune encephalomyelitis in C57BL /6 mice at multiple levels Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12 Selective immunointervention in autoimmune diseases: lessons from multiple sclerosis.Cyclophosphamide in multiple sclerosis: scientific rationale, history and novel treatment paradigms.Lights and shadows of cyclophosphamide in the treatment of multiple sclerosis Cytokines in multiple sclerosis: methodological aspects and pathogenic implications.Neutrophil-related factors as biomarkers in EAE and MS.Cytokine-based immunointervention in the treatment of autoimmune diseases.Influence of histocompatibility genes on disease susceptibility and treatment response in patients with relapsing-remitting multiple sclerosis treated with interferon β-1a.Inhibiting cytokines of the interleukin-12 family: recent advances and novel challenges.Myelin/axonal pathology in interleukin-12 induced serial relapses of experimental allergic encephalomyelitis in the Lewis rat Interleukin 12 (IL-12) family cytokines: Role in immune pathogenesis and treatment of CNS autoimmune disease.Immunopathogenesis and immunotherapeutic approaches in multiple sclerosis.Pharmacological Approaches to the Management of Secondary Progressive Multiple Sclerosis.Effects of fumarates on circulating and CNS myeloid cells in multiple sclerosis.Peroxisome proliferator-activated receptor-alpha agonist fenofibrate regulates IL-12 family cytokine expression in the CNS: relevance to multiple sclerosis.Peroxisome proliferator-activated receptor-gamma agonists suppress the production of IL-12 family cytokines by activated glia.Increased IL-23 secretion and altered chemokine production by dendritic cells upon CD46 activation in patients with multiple sclerosis.Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE.A cytokine study in children and adolescents with Tourette's disorder Vitiligo, reactive oxygen species and T-cells.Pathogenesis of pediatric multiple sclerosis.Immunotherapy of multiple sclerosis: the state of the art.The experimental autoimmune encephalomyelitis (EAE) model of MS: utility for understanding disease pathophysiology and treatment.Biomarker studies in multiple sclerosis: from proteins to noncoding RNAs.EBV and vitamin D status in relapsing-remitting multiple sclerosis patients with a unique cytokine signature.Efficacy of Different Durations of Intravenous Methylprednisolone Treatment in Relapses of Multiple Sclerosis.Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis.Attenuation of islet-specific T cell responses is associated with C-peptide improvement in autoimmune type 2 diabetes patients.Circulating lymphocyte subsets linked to intracellular cytokine profiles in normal humans.Characterization of plasma cytokines in an infant population cohort of challenge-proven food allergy.A randomized blinded trial of combination therapy with cyclophosphamide in patients-with active multiple sclerosis on interferon beta.

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Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy.

http://www.wikidata.org/entity/Q37384434

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on August 1998

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Elevated interleukin-12 in pro ...... ulse cyclophosphamide therapy.

@en

Elevated interleukin-12 in pro ...... ulse cyclophosphamide therapy.

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type

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Elevated interleukin-12 in pro ...... ulse cyclophosphamide therapy.

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Elevated interleukin-12 in pro ...... ulse cyclophosphamide therapy.

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prefLabel

Elevated interleukin-12 in pro ...... ulse cyclophosphamide therapy.

@en

Elevated interleukin-12 in pro ...... ulse cyclophosphamide therapy.

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Journal of Clinical Investigation

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Elevated interleukin-12 in pro ...... ulse cyclophosphamide therapy.

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D Smith

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H L Weiner

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K Balashov

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M Comabella

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S Issazadeh

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S J Khoury

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P2860

Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins

Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

Intensive immunosuppression in progressive multiple sclerosis. A randomized, three-arm study of high-dose intravenous cyclophosphamide, plasma exchange, and ACTH.

Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12.

Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis.

Detection of altered T helper 1 and T helper 2 cytokine production by peripheral blood mononuclear cells in patients with multiple sclerosis utilizing intracellular cytokine detection by flow cytometry and surface marker analysis.

Increased interleukin 12 production in progressive multiple sclerosis: induction by activated CD4+ T cells via CD40 ligand.

Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease.

Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming.

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multiple sclerosis

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