A role for HDJ-2/HSDJ in correcting subnuclear trafficking, transactivation, and transrepression defects of a glucocorticoid receptor zinc finger mutant
about
Glucocorticoid receptor homodimers and glucocorticoid-mineralocorticoid receptor heterodimers form in the cytoplasm through alternative dimerization interfacesMammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclatureIrs4p and Tax4p: two redundant EH domain proteins involved in autophagy.Human DnaJ homologs dj2 and dj3, and bag-1 are positive cochaperones of hsc70Protein 14-3-3sigma interacts with and favors cytoplasmic subcellular localization of the glucocorticoid receptor, acting as a negative regulator of the glucocorticoid signaling pathwayPaeoniflorin, a novel heat shock protein-inducing compound.Gene expression in the rat supraoptic nucleus induced by chronic hyperosmolality versus hyposmolalityImportin 7 and importin alpha/importin beta are nuclear import receptors for the glucocorticoid receptor.Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone.Molecular chaperone function of mammalian Hsp70 and Hsp40--a review.Lipid posttranslational modifications. Farnesyl transferase inhibitors.Inducers and co-inducers of molecular chaperones.Farnesylation of Ydj1 is required for in vivo interaction with Hsp90 client proteins.Discrimination between NL1- and NL2-mediated nuclear localization of the glucocorticoid receptorEndogenous glucocorticoids and impaired insulin signaling are both required to stimulate muscle wasting under pathophysiological conditions in mice.Molecular pharmacology of glucocorticoids: recent advances and future perspectives.Nucleocytoplasmic trafficking of steroid-free glucocorticoid receptor.Overexpression of HDJ-2 protects astrocytes from ischemia-like injury and reduces redistribution of ubiquitin staining in vitro.A serine/threonine-rich motif is one of three nuclear localization signals that determine unidirectional transport of the mineralocorticoid receptor to the nucleus.Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.
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P2860
A role for HDJ-2/HSDJ in correcting subnuclear trafficking, transactivation, and transrepression defects of a glucocorticoid receptor zinc finger mutant
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1997
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A role for HDJ-2/HSDJ in corre ...... id receptor zinc finger mutant
@en
A role for HDJ-2/HSDJ in corre ...... d receptor zinc finger mutant.
@nl
type
label
A role for HDJ-2/HSDJ in corre ...... id receptor zinc finger mutant
@en
A role for HDJ-2/HSDJ in corre ...... d receptor zinc finger mutant.
@nl
prefLabel
A role for HDJ-2/HSDJ in corre ...... id receptor zinc finger mutant
@en
A role for HDJ-2/HSDJ in corre ...... d receptor zinc finger mutant.
@nl
P2093
P2860
P356
P1476
A role for HDJ-2/HSDJ in corre ...... id receptor zinc finger mutant
@en
P2093
C Ramakrishnan
D B DeFranco
P2860
P304
P356
10.1091/MBC.8.5.795
P577
1997-05-01T00:00:00Z