CDK1 phosphorylation of YAP promotes mitotic defects and cell motility and is essential for neoplastic transformation.
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Regulation of TAZ in cancerAmyloid precursor protein and amyloid precursor-like protein 2 in cancerMechanisms of Hippo pathway regulationA Review: Molecular Aberrations within Hippo Signaling in Bone and Soft-Tissue SarcomasConnections between cadherin-catenin proteins, spindle misorientation, and cancerYAP and TAZ: a nexus for Hippo signaling and beyondCytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP.KIBRA: In the brain and beyondOncoprotein YAP regulates the spindle checkpoint activation in a mitotic phosphorylation-dependent manner through up-regulation of BubR1.The hippo pathway effector YAP regulates motility, invasion, and castration-resistant growth of prostate cancer cells.Adhesion glycoprotein CD44 functions as an upstream regulator of a network connecting ERK, AKT and Hippo-YAP pathways in cancer progressionPhotoreceptor proliferation and dysregulation of cell cycle genes in early onset inherited retinal degenerations.CDK1 phosphorylation of TAZ in mitosis inhibits its oncogenic activityActive YAP promotes pancreatic cancer cell motility, invasion and tumorigenesis in a mitotic phosphorylation-dependent manner through LPAR3YAP induces high-grade serous carcinoma in fallopian tube secretory epithelial cells.KIBRA promotes prostate cancer cell proliferation and motility.Yap1 promotes the survival and self-renewal of breast tumor initiating cells via inhibiting Smad3 signalingAjuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis.Phosphorylation of Tyr188 in the WW domain of YAP1 plays an essential role in YAP1-induced cellular transformationThe mammalian Hippo pathway: regulation and function of YAP1 and TAZ.The regulation and function of YAP transcription co-activator.Drug development against the hippo pathway in mesotheliomaTransformation by Polyomavirus Middle T Antigen Involves a Unique Bimodal Interaction with the Hippo Effector YAP.Sensitivity to cdk1-inhibition is modulated by p53 status in preclinical models of embryonal tumors.Polyomavirus small T antigen interacts with yes-associated protein to regulate cell survival and differentiation.Regulation of Tissue Growth by the Mammalian Hippo Signaling Pathway.p53 shades of Hippo.The Role of Hippo Pathway in Cancer Stem Cell Biology.Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2.Cyclin-dependent kinase 1 (CDK1)-mediated mitotic phosphorylation of the transcriptional co-repressor Vgll4 inhibits its tumor-suppressing activity.Hippo Signaling in Mitosis: An Updated View in Light of the MEN Pathway.MST2 phosphorylation at serine 385 in mitosis inhibits its tumor suppressing activity.Cyclizing-berberine A35 induces G2/M arrest and apoptosis by activating YAP phosphorylation (Ser127).Overexpression of CBX3 in Pancreatic Adenocarcinoma Promotes Cell Cycle Transition-Associated Tumor Progression.Liver regeneration in aged mice: new insights
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CDK1 phosphorylation of YAP promotes mitotic defects and cell motility and is essential for neoplastic transformation.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 07 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
CDK1 phosphorylation of YAP pr ...... for neoplastic transformation.
@en
CDK1 phosphorylation of YAP pr ...... for neoplastic transformation.
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type
label
CDK1 phosphorylation of YAP pr ...... for neoplastic transformation.
@en
CDK1 phosphorylation of YAP pr ...... for neoplastic transformation.
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prefLabel
CDK1 phosphorylation of YAP pr ...... for neoplastic transformation.
@en
CDK1 phosphorylation of YAP pr ...... for neoplastic transformation.
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P2093
P2860
P1433
P1476
CDK1 phosphorylation of YAP pr ...... for neoplastic transformation.
@en
P2093
Jixin Dong
Rong Chong
Shi-Jian Ding
Shuping Yang
Yuanhong Chen
P2860
P304
P356
10.1158/0008-5472.CAN-13-2049
P407
P577
2013-10-07T00:00:00Z