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Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivoGenome-wide association study identifies five new susceptibility loci for primary angle closure glaucomaGenetic variants in novel pathways influence blood pressure and cardiovascular disease riskSix new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humansCommon missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrationsThe APOA5 locus is a strong determinant of plasma triglyceride concentrations across ethnic groups in SingaporeIntragenic linkage disequilibrium structure of the human perilipin gene (PLIN) and haplotype association with increased obesity risk in a multiethnic Asian populationClinical significance of apolipoprotein A5The role of perilipin in human obesity and insulin resistanceNew measure of insulin sensitivity predicts cardiovascular disease better than HOMA estimated insulin resistanceLow-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibilityGene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP ConsortiaCholesterol-raising diterpenes in types of coffee commonly consumed in Singapore, Indonesia and India and associations with blood lipids: a survey and cross sectional studyA genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility lociGenome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from IndiaGenome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibilityInsights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.Genome-wide association study identifies ZFHX1B as a susceptibility locus for severe myopia.Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility lociMeta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.The genetic architecture of type 2 diabetesFTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals.Metabolic syndrome and risk of age-related cataract over time: an analysis of interval-censored data using a random-effects model.Associations of diabetes mellitus and ethnicity with mortality in a multiethnic Asian population: data from the 1992 Singapore National Health Survey.The metabolic syndrome in Chinese, Malays and Asian Indians. Factor analysis of data from the 1998 Singapore National Health Survey.Validity of the International Physical Activity Questionnaire and the Singapore Prospective Study Program physical activity questionnaire in a multiethnic urban Asian population.The case for strategic international alliances to harness nutritional genomics for public and personal health.Quantitative retinal vascular calibre changes in diabetes and retinopathy: the Singapore Malay eye study.Retinal microvascular caliber and chronic kidney disease in an Asian population.Establishing the thematic framework for a diabetes-specific health-related quality of life item bank for use in an english-speaking asian population.A natural polymorphism in peroxisome proliferator-activated receptor-alpha hinge region attenuates transcription due to defective release of nuclear receptor corepressor from chromatin.Identification of new genetic risk variants for type 2 diabetes.Patterns of physical activity in different domains and implications for intervention in a multi-ethnic Asian population: a cross-sectional study.Loss-of-function mutations in SLC30A8 protect against type 2 diabetesPopulation differences in associations of serotonin transporter promoter polymorphism (5HTTLPR) di- and triallelic genotypes with blood pressure and hypertension prevalence.Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children.Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.The ARIC predictive model reliably predicted risk of type II diabetes in Asian populations.Allele frequencies of variants in ultra conserved elements identify selective pressure on transcription factor bindingTrans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
P50
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P50
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hulumtues
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հետազոտող
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E Shyong Tai
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E Shyong Tai
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E Shyong Tai
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E Shyong Tai
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E Shyong Tai
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E Shyong Tai
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E Shyong Tai
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E Shyong Tai
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E Shyong Tai
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E Shyong Tai
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E Shyong Tai
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E Shyong Tai
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E Shyong Tai
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E Shyong Tai
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E Shyong Tai
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P106
P1153
7005660980
P21
P31
P496
0000-0003-2929-8966