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Direct selection for ribozyme cleavage activity in cells

Direct selection for ribozyme cleavage activity in cells

http://www.wikidata.org/entity/Q37393572

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The hammerhead ribozyme: structure, catalysis, and gene regulation A high-throughput, quantitative cell-based screen for efficient tailoring of RNA device activity.Enhanced group II intron retrohoming in magnesium-deficient Escherichia coli via selection of mutations in the ribozyme core.Low selection pressure aids the evolution of cooperative ribozyme mutations in cells Design and application of cotranscriptional non-enzymatic RNA circuits and signal transducers.Aptamers for allosteric regulation.Engineering biological systems with synthetic RNA molecules.Engineered riboswitches: Expanding researchers' toolbox with synthetic RNA regulators.Intron cleavage affects processing of alternatively spliced transcripts.In vivo evolution of a catalytic RNA couples trans-splicing to translation.Spiegelzymes® mirror-image hammerhead ribozymes and mirror-image DNAzymes, an alternative to siRNAs and microRNAs to cleave mRNAs in vivo?Prediction of hammerhead ribozyme intracellular activity with the catalytic core fingerprint.Direct screening for ribozyme activity in mammalian cells.Engineering protein-protein devices for multilayered regulation of mRNA translation using orthogonal proteases in mammalian cells

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Direct selection for ribozyme cleavage activity in cells

http://www.wikidata.org/entity/Q37393572

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

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scientific article published on 23 September 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Direct selection for ribozyme cleavage activity in cells

@en

Direct selection for ribozyme cleavage activity in cells.

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type

label

Direct selection for ribozyme cleavage activity in cells

@en

Direct selection for ribozyme cleavage activity in cells.

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prefLabel

Direct selection for ribozyme cleavage activity in cells

@en

Direct selection for ribozyme cleavage activity in cells.

@nl

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Direct selection for ribozyme cleavage activity in cells

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Andrew D Ellington

http://www.w3.org/2001/XMLSchema#string

Lisa Denison

http://www.w3.org/2001/XMLSchema#string

Matthew Levy

http://www.w3.org/2001/XMLSchema#string

Xi Chen

http://www.w3.org/2001/XMLSchema#string

P2860

In vitro evolution suggests multiple origins for the hammerhead ribozyme

Schistosome satellite DNA encodes active hammerhead ribozymes

Higher-order cellular information processing with synthetic RNA devices

A discontinuous hammerhead ribozyme embedded in a mammalian messenger RNA

Peripheral regions of natural hammerhead ribozymes greatly increase their self-cleavage activity

Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

Sequence elements outside the hammerhead ribozyme catalytic core enable intracellular activity

Tertiary contacts distant from the active site prime a ribozyme for catalysis.

A high-throughput screen for synthetic riboswitches reveals mechanistic insights into their function

Detection of antisense and ribozyme accessible sites on native mRNAs: application to NCOA3 mRNA.

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2035-2045

http://www.w3.org/2001/XMLSchema#string

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scholarly article

P356

10.1261/RNA.1635209

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11

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15

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2009-09-23T00:00:00Z

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26833258

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19776159

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2764470

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