A novel C5a-neutralizing mirror-image (l-)aptamer prevents organ failure and improves survival in experimental sepsis - Wikidata - awgldk - TriplyDB

A novel C5a-neutralizing mirror-image (l-)aptamer prevents organ failure and improves survival in experimental sepsis

A novel C5a-neutralizing mirror-image (l-)aptamer prevents organ failure and improves survival in experimental sepsis

http://www.wikidata.org/entity/Q37393792

about

Aptamers: A Feasible Technology in Cancer Immunotherapy Expected and unexpected features of protein-binding RNA aptamers Structural and functional characterization of human and murine C5a anaphylatoxins New milestones ahead in complement-targeted therapy.Aptamers: new arrows to target dendritic cells.Intravitreal inhibition of complement C5a reduces choroidal neovascularization in mice.A novel CGRP-neutralizing Spiegelmer attenuates neurogenic plasma protein extravasation Anti-inflammatory interventions-what has worked, not worked, and what may work in the future.Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer.Identification and characterization of a mirror-image oligonucleotide that binds and neutralizes sphingosine 1-phosphate, a central mediator of angiogenesis.Ouabain rescues rat nephrogenesis during intrauterine growth restriction by regulating the complement and coagulation cascades and calcium signaling pathway.Status and Prospects of Aptamers as Drug Components.Necroinflammation in Kidney Disease.Targeted complement inhibition and microvasculature in transplants: a therapeutic perspective.Recent Advances in Aptamers Targeting Immune System.Complement in Pancreatic Disease-Perpetrator or Savior?Development of Autologous C5 Vaccine Nanoparticles to Reduce Intravascular Hemolysis in Vivo.Carboxypeptidase B2 deficiency reveals opposite effects of complement C3a and C5a in a murine polymicrobial sepsis model.Signaling of the Complement Cleavage Product Anaphylatoxin C5a Through C5aR (CD88) Contributes to Pharmacological Hematopoietic Stem Cell Mobilization.Chemical modifications of nucleic acid drugs and their delivery systems for gene-based therapy.Complement system modulation as a target for treatment of arrhythmogenic cardiomyopathy.(Meth)acrylated poly(ethylene glycol)s as precursors for rheology modifiers, superplasticizers and electrolyte membranes: a review Be on Target: Strategies of Targeting Alternative and Lectin Pathway Components in Complement-Mediated Diseases

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P2860

A novel C5a-neutralizing mirror-image (l-)aptamer prevents organ failure and improves survival in experimental sepsis

http://www.wikidata.org/entity/Q37393792

description

2013 nî lūn-bûn

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2013年の論文

@ja

2013年学术文章

@wuu

2013年学术文章

@zh

2013年学术文章

@zh-cn

2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

2013年學術文章

@zh-hant

name

A novel C5a-neutralizing mirro ...... urvival in experimental sepsis

@en

A novel C5a-neutralizing mirror-image

@nl

type

label

A novel C5a-neutralizing mirro ...... urvival in experimental sepsis

@en

A novel C5a-neutralizing mirror-image

@nl

prefLabel

A novel C5a-neutralizing mirro ...... urvival in experimental sepsis

@en

A novel C5a-neutralizing mirror-image

@nl

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Molecular Therapy

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A novel C5a-neutralizing mirro ...... urvival in experimental sepsis

@en

P2093

Christian Maasch

http://www.w3.org/2001/XMLSchema#string

Kai Hoehlig

http://www.w3.org/2001/XMLSchema#string

Klaus Buchner

http://www.w3.org/2001/XMLSchema#string

Nelli Shushakova

http://www.w3.org/2001/XMLSchema#string

Sven Klussmann

http://www.w3.org/2001/XMLSchema#string

Werner G Purschke

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P2860

Long-term cognitive impairment and functional disability among survivors of severe sepsis

The Vienna RNA websuite

The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74)

Complement-induced impairment of innate immunity during sepsis

The chemotactic receptor for human C5a anaphylatoxin

International Union of Basic and Clinical Pharmacology. [corrected]. LXXXVII. Complement peptide C5a, C4a, and C3a receptors

Inhibition of immune-complex mediated dermal inflammation in rats following either oral or topical administration of a small molecule C5a receptor antagonist

Complement: a key system for immune surveillance and homeostasis

Mirror-image RNA that binds D-adenosine.

The effects of the anti-hepcidin Spiegelmer NOX-H94 on inflammation-induced anemia in cynomolgus monkeys.

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2236-2246

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scholarly article

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10.1038/MT.2013.178

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12

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21

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Markus S Huber-Lang

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2013-07-26T00:00:00Z

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252325051

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23887360

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3863792

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