The role of Abeta-induced calcium dysregulation in the pathogenesis of Alzheimer's disease.
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The Amyloid Precursor Protein-A Novel Player within the Molecular Array of Presynaptic NanomachinesMetabolic methanol: molecular pathways and physiological rolesMitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptotic cell deathAmyloid β-peptide directly induces spontaneous calcium transients, delayed intercellular calcium waves and gliosis in rat cortical astrocytesPresenilins and the gamma-secretase: still a complex problem.Two-step mechanism of membrane disruption by Aβ through membrane fragmentation and pore formationBACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer's diseaseAmyloid-β plaques disrupt axon initial segments.Multiple effects of β-amyloid on single excitatory synaptic connections in the PFC.A 10-year follow-up study of the association between calcium channel blocker use and the risk of dementia in elderly hypertensive patientsDiscovery of candidate genes for muscle traits based on GWAS supported by eQTL-analysis.Calcium channel blockers and dementia.Loss of stability and hydrophobicity of presenilin 1 mutations causing Alzheimer's disease.Amlodipine treatment of hypertension associates with a decreased dementia risk.Amyloid β1-42 (Aβ1-42) Induces the CDK2-Mediated Phosphorylation of Tau through the Activation of the mTORC1 Signaling Pathway While Promoting Neuronal Cell Death.Effects of amyloid-β peptides on voltage-gated L-type Ca(V)1.2 and Ca(V)1.3 Ca(2+) channelsProtective Effects of Proline-Rich Peptide in a Rat Model of Alzheimer Disease: An Electrophysiological Study.Effect of Metal Chelators on γ-Secretase Indicates That Calcium and Magnesium Ions Facilitate Cleavage of Alzheimer Amyloid Precursor Substrate.Single-cell screening of cytosolic [Ca(2+)] reveals cell-selective action by the Alzheimer's Aβ peptide ion channel.Curcumin attenuates amyloid-β-induced tau hyperphosphorylation in human neuroblastoma SH-SY5Y cells involving PTEN/Akt/GSK-3β signaling pathway.Protective effects of hesperidin against amyloid-β (Aβ) induced neurotoxicity through the voltage dependent anion channel 1 (VDAC1)-mediated mitochondrial apoptotic pathway in PC12 cells.Analyzing the Behavior of Neuronal Pathways in Alzheimer's Disease Using Petri Net Modeling Approach.
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P2860
The role of Abeta-induced calcium dysregulation in the pathogenesis of Alzheimer's disease.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2009
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
The role of Abeta-induced calc ...... enesis of Alzheimer's disease.
@en
The role of Abeta-induced calc ...... enesis of Alzheimer's disease.
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type
label
The role of Abeta-induced calc ...... enesis of Alzheimer's disease.
@en
The role of Abeta-induced calc ...... enesis of Alzheimer's disease.
@nl
prefLabel
The role of Abeta-induced calc ...... enesis of Alzheimer's disease.
@en
The role of Abeta-induced calc ...... enesis of Alzheimer's disease.
@nl
P2093
P356
P1476
The role of Abeta-induced calc ...... genesis of Alzheimer's disease
@en
P2093
Adele J Vincent
Amos C Hung
David H Small
P304
P356
10.3233/JAD-2009-0951
P577
2009-01-01T00:00:00Z