Effect of amino acid substitutions on the catalytic and regulatory properties of aspartate transcarbamoylase.
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Human ornithine transcarbamylase: crystallographic insights into substrate recognition and conformational changesArginine 54 in the active site of escherichia coli aspartate transcarbamoylase is critical for catalysis: A site-specific mutagenesis, NMR, and X-ray crystallographic studyThe first high pH structure ofEscherichia coliaspartate transcarbamoylaseChanges in stability and allosteric properties of aspartate transcarbamoylase resulting from amino acid substitutions in the zinc-binding domain of the regulatory chains.Shared active sites in oligomeric enzymes: model studies with defective mutants of aspartate transcarbamoylase produced by site-directed mutagenesis.An efficient approach to identify ilvA mutations reveals an amino-terminal catalytic domain in biosynthetic threonine deaminase from Escherichia coliThe allosteric activator ATP induces a substrate-dependent alteration of the quaternary structure of a mutant aspartate transcarbamoylase impaired in active site closureStructural similarity between ornithine and aspartate transcarbamoylases of Escherichia coli: characterization of the active site and evidence for an interdomain carboxy-terminal helix in ornithine transcarbamoylase.The 80s loop of the catalytic chain of Escherichia coli aspartate transcarbamoylase is critical for catalysis and homotropic cooperativityThe regulatory subunit of Escherichia coli aspartate carbamoyltransferase may influence homotropic cooperativity and heterotropic interactions by a direct interaction with the loop containing residues 230-245 of the catalytic chain.Aspartate Transcarbamylase from Escherichia Coli: Activity and Regulation
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Effect of amino acid substitutions on the catalytic and regulatory properties of aspartate transcarbamoylase.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 1986
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Effect of amino acid substitut ...... f aspartate transcarbamoylase.
@en
Effect of amino acid substitut ...... f aspartate transcarbamoylase.
@nl
type
label
Effect of amino acid substitut ...... f aspartate transcarbamoylase.
@en
Effect of amino acid substitut ...... f aspartate transcarbamoylase.
@nl
prefLabel
Effect of amino acid substitut ...... f aspartate transcarbamoylase.
@en
Effect of amino acid substitut ...... f aspartate transcarbamoylase.
@nl
P2093
P2860
P356
P1476
Effect of amino acid substitut ...... f aspartate transcarbamoylase.
@en
P2093
P2860
P304
P356
10.1073/PNAS.83.16.5934
P407
P577
1986-08-01T00:00:00Z