Histone hyperacetylation within the beta-globin locus is context-dependent and precedes high-level gene expression.
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Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter bindingNucleosome Dancing at the Tempo of Histone Tail AcetylationThe chromatin "landscape" of a murine adult β-globin gene is unaffected by deletion of either the gene promoter or a downstream enhancer.An embryonic stage-specific enhancer within the murine β-globin locus mediates domain-wide histone hyperacetylation.Prevention of transcriptional silencing by a replicator-binding complex consisting of SWI/SNF, MeCP1, and hnRNP C1/C2.Chromatin looping and eRNA transcription precede the transcriptional activation of gene in the β-globin locus.Gene induction and repression during terminal erythropoiesis are mediated by distinct epigenetic changes.Gene insulation. Part II: natural strategies in vertebrates.
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P2860
Histone hyperacetylation within the beta-globin locus is context-dependent and precedes high-level gene expression.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Histone hyperacetylation withi ...... es high-level gene expression.
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Histone hyperacetylation withi ...... es high-level gene expression.
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label
Histone hyperacetylation withi ...... es high-level gene expression.
@en
Histone hyperacetylation withi ...... es high-level gene expression.
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Histone hyperacetylation withi ...... es high-level gene expression.
@en
Histone hyperacetylation withi ...... es high-level gene expression.
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Histone hyperacetylation withi ...... es high-level gene expression.
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Christina de Vries
George Fromm
James Palis
Jennifer Fields
M A Bender
Mark Groudine
Michael Bulger
Rachel Byron
Steven Fiering
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P304
P356
10.1182/BLOOD-2009-03-210690
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P577
2009-08-18T00:00:00Z