HIPK2 modulates p53 activity towards pro-apoptotic transcription.
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Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategiesAcetylation of the pro-apoptotic factor, p53 in the hippocampus following cerebral ischemia and modulation by estrogenp53 Acetylation: Regulation and ConsequencesAdaptive patterns in the p53 protein sequence of the hypoxia- and cancer-tolerant blind mole rat SpalaxInterplay between Mdm2 and HIPK2 in the DNA damage response.HIV infection upregulates caveolin 1 expression to restrict virus production.Zinc bells rang in Jerusalem!High glucose dephosphorylates serine 46 and inhibits p53 apoptotic activityUnfolded p53 in the pathogenesis of Alzheimer's disease: is HIPK2 the link?Verbascoside promotes apoptosis by regulating HIPK2-p53 signaling in human colorectal cancerKAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genesZfra is a small wizard in the mitochondrial apoptosisHIF-1α antagonizes p53-mediated apoptosis by triggering HIPK2 degradation.Genomic imbalances in esophageal carcinoma cell lines involve Wnt pathway genesGenome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation.HIF-1α Plays a Critical Role in the Gestational Sidestream Smoke-Induced Bronchopulmonary Dysplasia in Mice.Feedbacks, Bifurcations, and Cell Fate Decision-Making in the p53 SystemUpdates on HIPK2: a resourceful oncosuppressor for clearing cancerTargeting COX-2/PGE(2) pathway in HIPK2 knockdown cancer cells: impact on dendritic cell maturation.Estrogen receptors β1 and β2 have opposing roles in regulating proliferation and bone metastasis genes in the prostate cancer cell line PC3.HIPK2 restricts SIRT1 activity upon severe DNA damage by a phosphorylation-controlled mechanismGlucose restriction induces cell death in parental but not in homeodomain-interacting protein kinase 2-depleted RKO colon cancer cells: molecular mechanisms and implications for tumor therapyGentian violet induces wtp53 transactivation in cancer cellsHomeodomain-interacting protein kinase 2 (HIPK2): a promising target for anti-cancer therapies.How the TP53 family proteins TP63 and TP73 contribute to tumorigenesis: regulators and effectors.Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors.G45R on nonstructural protein 1 of influenza A virus contributes to virulence by increasing the expression of proinflammatory cytokines in mice.HIPK2 modification code for cell death and survival.The Tyrosine Kinase c-Abl Promotes Homeodomain-interacting Protein Kinase 2 (HIPK2) Accumulation and Activation in Response to DNA Damage.Down-regulation of wild-type p53-induced phosphatase 1 (Wip1) plays a critical role in regulating several p53-dependent functions in premature senescent tumor cells.Expression patterns and potential roles of SIRT1 in human medulloblastoma cells in vivo and in vitro.Measurement of the cellular deacetylase activity of SIRT1 on p53 via LanthaScreen® technology.Counteracting MDM2-induced HIPK2 downregulation restores HIPK2/p53 apoptotic signaling in cancer cells.Variant 2 of KIAA0101, antagonizing its oncogenic variant 1, might be a potential therapeutic strategy in hepatocellular carcinoma.Different functions of HIPK2 and CtBP2 in traumatic brain injury.p300-mediated acetylation increased the protein stability of HIPK2 and enhanced its tumor suppressor function.Tumor suppressive role for kinases phosphorylating p53 in DNA damage-induced apoptosis
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HIPK2 modulates p53 activity towards pro-apoptotic transcription.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 14 October 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
HIPK2 modulates p53 activity towards pro-apoptotic transcription.
@en
HIPK2 modulates p53 activity towards pro-apoptotic transcription.
@nl
type
label
HIPK2 modulates p53 activity towards pro-apoptotic transcription.
@en
HIPK2 modulates p53 activity towards pro-apoptotic transcription.
@nl
prefLabel
HIPK2 modulates p53 activity towards pro-apoptotic transcription.
@en
HIPK2 modulates p53 activity towards pro-apoptotic transcription.
@nl
P2093
P2860
P356
P1433
P1476
HIPK2 modulates p53 activity towards pro-apoptotic transcription.
@en
P2093
Ada Sacchi
David Givol
Gabriella D'Orazi
Gideon Rechavi
Lavinia Nardinocchi
P2860
P2888
P356
10.1186/1476-4598-8-85
P577
2009-10-14T00:00:00Z
P5875
P6179
1030991805