Affinity for phosphatidylinositol 4,5-bisphosphate determines muscarinic agonist sensitivity of Kv7 K+ channels.
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Driving with no brakes: molecular pathophysiology of Kv7 potassium channelsPotent KCNQ2/3-specific channel activator suppresses in vivo epileptic activity and prevents the development of tinnitusCa2+/calmodulin disrupts AKAP79/150 interactions with KCNQ (M-Type) K+ channelsTriggering actin comets versus membrane ruffles: distinctive effects of phosphoinositides on actin reorganizationA genetically encoded tool kit for manipulating and monitoring membrane phosphatidylinositol 4,5-bisphosphate in intact cells.Combined phosphoinositide and Ca2+ signals mediating receptor specificity toward neuronal Ca2+ channels.Tamoxifen inhibition of kv7.2/kv7.3 channelsPhosphoinositides regulate ion channels.The M-current contributes to high threshold membrane potential oscillations in a cell type-specific way in the pedunculopontine nucleus of micePhosphoinositide control of membrane protein function: a frontier led by studies on ion channels.The Role of the Carboxyl Terminus Helix C-D Linker in Regulating KCNQ3 K+ Current Amplitudes by Controlling Channel TraffickingUse of virtual cell in studies of cellular dynamics.The Voltage Activation of Cortical KCNQ Channels Depends on Global PIP2 Levels.Phosphatidylinositol 4,5-bisphosphate alters pharmacological selectivity for epilepsy-causing KCNQ potassium channelsChannelopathies linked to plasma membrane phosphoinositides.Regulation of ion channels by membrane lipids.Phosphorylation regulates the sensitivity of voltage-gated Kv7.2 channels towards phosphatidylinositol-4,5-bisphosphate.Essential role for phosphatidylinositol 4,5-bisphosphate in the expression, regulation, and gating of the slow afterhyperpolarization current in the cerebral cortex.A basic residue in the proximal C-terminus is necessary for efficient activation of the M-channel subunit Kv7.2 by PI(4,5)P₂.Distinct subunit contributions to the activation of M-type potassium channels by PI(4,5)P2.The calcium-activated slow AHP: cutting through the Gordian knot.Restoration of ion channel function in deafness-causing KCNQ4 mutants by synthetic channel openers.Ion channel regulation by phosphoinositides analyzed with VSPs-PI(4,5)P2 affinity, phosphoinositide selectivity, and PI(4,5)P2 pool accessibility.Characterization of a binding site for anionic phospholipids on KCNQ1.Probing the regulation of TASK potassium channels by PI4,5P₂ with switchable phosphoinositide phosphatases.Intracellular zinc activates KCNQ channels by reducing their dependence on phosphatidylinositol 4,5-bisphosphate.A Calmodulin C-Lobe Ca2+-Dependent Switch Governs Kv7 Channel Function.
P2860
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P2860
Affinity for phosphatidylinositol 4,5-bisphosphate determines muscarinic agonist sensitivity of Kv7 K+ channels.
description
2009 nî lūn-bûn
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2009年の論文
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2009年学术文章
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2009年学术文章
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2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
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2009年學術文章
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2009年學術文章
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2009年學術文章
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name
Affinity for phosphatidylinosi ...... ensitivity of Kv7 K+ channels.
@en
Affinity for phosphatidylinosi ...... ensitivity of Kv7 K+ channels.
@nl
type
label
Affinity for phosphatidylinosi ...... ensitivity of Kv7 K+ channels.
@en
Affinity for phosphatidylinosi ...... ensitivity of Kv7 K+ channels.
@nl
prefLabel
Affinity for phosphatidylinosi ...... ensitivity of Kv7 K+ channels.
@en
Affinity for phosphatidylinosi ...... ensitivity of Kv7 K+ channels.
@nl
P2093
P2860
P356
P1476
Affinity for phosphatidylinosi ...... ensitivity of Kv7 K+ channels.
@en
P2093
Björn Falkenburger
Ciria C Hernandez
Mark S Shapiro
P2860
P304
P356
10.1085/JGP.200910313
P577
2009-11-01T00:00:00Z