MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.
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New insights into the roles of microRNAs in drug addiction and neuroplasticityThe effects of microRNA on the absorption, distribution, metabolism and excretion of drugsVitamin D and microRNAs in boneKey Targets for Multi-Target Ligands Designed to Combat NeurodegenerationMiRNAs and miRNA Polymorphisms Modify Drug ResponseModulation of the rat hepatic cytochrome P4501A subfamily using biotin supplementationPatient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicityGenetic variation in the 3'-UTR of CYP1A2, CYP2B6, CYP2D6, CYP3A4, NR1I2, and UGT2B7: potential effects on regulation by microRNA and pharmacogenomics relevance.Pharmaco-miR: linking microRNAs and drug effects.Pharmacogenomics of oral antidiabetic medications: current data and pharmacoepigenomic perspective.Molecular targets of epigenetic regulation and effectors of environmental influencesSpecies-specific microRNA roles elucidated following astrocyte activation.Rapid production of novel pre-microRNA agent hsa-mir-27b in Escherichia coli using recombinant RNA technology for functional studies in mammalian cells.Prenatal exposure to TCDD triggers significant modulation of microRNA expression profile in the thymus that affects consequent gene expressionDrug-metabolizing enzyme, transporter, and nuclear receptor genetically modified mouse models.miR-296-3p, miR-298-5p and their downstream networks are causally involved in the higher resistance of mammalian pancreatic α cells to cytokine-induced apoptosis as compared to β cellsBreast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328, -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cellsVitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects.Sucralose, a synthetic organochlorine sweetener: overview of biological issuesmiR-520b regulates migration of breast cancer cells by targeting hepatitis B X-interacting protein and interleukin-8Relationship between differential hepatic microRNA expression and decreased hepatic cytochrome P450 3A activity in cirrhosisStructure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2.In silico identification of microRNAs predicted to regulate the drug metabolizing cytochrome P450 genesMicroRNA-mediated drug resistance in breast cancer.MicroRNA expression is differentially altered by xenobiotic drugs in different human cell lines.1α,25(OH)2D3 differentially regulates miRNA expression in human bladder cancer cellsThe emerging role of microRNAs in drug responsesIntronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugsOntogenic expression of human carboxylesterase-2 and cytochrome P450 3A4 in liver and duodenum: postnatal surge and organ-dependent regulation.In silico and in vitro identification of microRNAs that regulate hepatic nuclear factor 4α expressionHuman CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liverThree new shRNA expression vectors targeting the CYP3A4 coding sequence to inhibit its expressionEpigenetic regulation of drug metabolism and transportNon-coding RNAs--novel targets in neurotoxicity.Pharmacogene regulatory elements: from discovery to applicationsMicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective TherapyPharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" ProblemmiRNA-27b levels are associated with CYP3A activity in vitro and in vivo.Locking-to-unlocking system is an efficient strategy to design DNA/silver nanoclusters (AgNCs) probe for human miRNAsThe independent contribution of miRNAs to the missing heritability in CYP3A4/5 functionality and the metabolism of atorvastatin.
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MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 06 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.
@en
MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.
@nl
type
label
MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.
@en
MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.
@nl
prefLabel
MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.
@en
MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.
@nl
P2093
P2860
P356
P1476
MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.
@en
P2093
Ai-Ming Yu
Wenqing Gao
Yu-Zhuo Pan
P2860
P304
P356
10.1124/DMD.109.027680
P577
2009-07-06T00:00:00Z