MicroRNAs regulate CYP3A4 expression via direct and indirect targeting. - Wikidata - awgldk - TriplyDB

MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.

MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.

http://www.wikidata.org/entity/Q37402750

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New insights into the roles of microRNAs in drug addiction and neuroplasticity The effects of microRNA on the absorption, distribution, metabolism and excretion of drugs Vitamin D and microRNAs in bone Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration MiRNAs and miRNA Polymorphisms Modify Drug Response Modulation of the rat hepatic cytochrome P4501A subfamily using biotin supplementation Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity Genetic variation in the 3'-UTR of CYP1A2, CYP2B6, CYP2D6, CYP3A4, NR1I2, and UGT2B7: potential effects on regulation by microRNA and pharmacogenomics relevance.Pharmaco-miR: linking microRNAs and drug effects.Pharmacogenomics of oral antidiabetic medications: current data and pharmacoepigenomic perspective.Molecular targets of epigenetic regulation and effectors of environmental influences Species-specific microRNA roles elucidated following astrocyte activation.Rapid production of novel pre-microRNA agent hsa-mir-27b in Escherichia coli using recombinant RNA technology for functional studies in mammalian cells.Prenatal exposure to TCDD triggers significant modulation of microRNA expression profile in the thymus that affects consequent gene expression Drug-metabolizing enzyme, transporter, and nuclear receptor genetically modified mouse models.miR-296-3p, miR-298-5p and their downstream networks are causally involved in the higher resistance of mammalian pancreatic α cells to cytokine-induced apoptosis as compared to β cells Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328, -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects.Sucralose, a synthetic organochlorine sweetener: overview of biological issues miR-520b regulates migration of breast cancer cells by targeting hepatitis B X-interacting protein and interleukin-8 Relationship between differential hepatic microRNA expression and decreased hepatic cytochrome P450 3A activity in cirrhosis Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2.In silico identification of microRNAs predicted to regulate the drug metabolizing cytochrome P450 genes MicroRNA-mediated drug resistance in breast cancer.MicroRNA expression is differentially altered by xenobiotic drugs in different human cell lines.1α,25(OH)2D3 differentially regulates miRNA expression in human bladder cancer cells The emerging role of microRNAs in drug responses Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs Ontogenic expression of human carboxylesterase-2 and cytochrome P450 3A4 in liver and duodenum: postnatal surge and organ-dependent regulation.In silico and in vitro identification of microRNAs that regulate hepatic nuclear factor 4α expression Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liver Three new shRNA expression vectors targeting the CYP3A4 coding sequence to inhibit its expression Epigenetic regulation of drug metabolism and transport Non-coding RNAs--novel targets in neurotoxicity.Pharmacogene regulatory elements: from discovery to applications MicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective Therapy Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" Problem miRNA-27b levels are associated with CYP3A activity in vitro and in vivo.Locking-to-unlocking system is an efficient strategy to design DNA/silver nanoclusters (AgNCs) probe for human miRNAs The independent contribution of miRNAs to the missing heritability in CYP3A4/5 functionality and the metabolism of atorvastatin.

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P2860

MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.

http://www.wikidata.org/entity/Q37402750

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 06 July 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.

@en

MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.

@nl

type

label

MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.

@en

MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.

@nl

prefLabel

MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.

@en

MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.

@nl

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Drug Metabolism and Disposition

P1476

MicroRNAs regulate CYP3A4 expression via direct and indirect targeting.

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P2093

Ai-Ming Yu

http://www.w3.org/2001/XMLSchema#string

Wenqing Gao

http://www.w3.org/2001/XMLSchema#string

Yu-Zhuo Pan

http://www.w3.org/2001/XMLSchema#string

P2860

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells

MicroInspector: a web tool for detection of miRNA binding sites in an RNA sequence.

The functions of animal microRNAs

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

MicroRNAs: small RNAs with a big role in gene regulation

MicroRNAs: genomics, biogenesis, mechanism, and function

MicroRNAs play a role in the development of human hematopoietic stem cells

Cytochrome P450 and xenobiotic receptor humanized mice.

Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin.

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2112-2117

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scholarly article

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10.1124/DMD.109.027680

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10

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37

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2009-07-06T00:00:00Z

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26651204

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19581388

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2769037

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