Two proto-oncogenes implicated in mammary carcinogenesis, int-1 and int-2, are independently regulated during mouse development.
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Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless.NoBP, a nuclear fibroblast growth factor 3 binding protein, is cell cycle regulated and promotes cell growthSOX6 binds CtBP2 to repress transcription from the Fgf-3 promoterCloning of the gene coding for human class 1 heparin-binding growth factor and its expression in fetal tissuesRapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primerMMTV-induced mammary tumorigenesis: gene discovery, progression to malignancy and cellular pathwaysRegulation of FGF-3 gene expression in tumorigenic and non-tumorigenic clones of a human colon carcinoma cell lineSOX7 and GATA-4 are competitive activators of Fgf-3 transcriptionMolecular cloning of a human basic fibroblast growth factor receptor cDNA and expression of a biologically active extracellular domain in a baculovirus system.Expression of cellular protooncogenes in the mouse male germ line: a distinctive 2.4-kilobase pim-1 transcript is expressed in haploid postmeiotic cellsA distinctive family of embryonic protein-tyrosine kinase receptors.Ligand-affinity cloning and structure of a cell surface heparan sulfate proteoglycan that binds basic fibroblast growth factor.Introduction of a lacZ reporter gene into the mouse int-2 locus by homologous recombinationExpression of int-2 oncogene in Kaposi's sarcoma lesions.The int-2 gene product acts as an epithelial growth factor in transgenic miceThe proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix.Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells.Inducible expression of FGF-3 in mouse mammary gland.Distinct developmental patterns of c-mos protooncogene expression in female and male mouse germ cells.Differential expression of the mouse homeobox-containing gene Hox-1.4 during male germ cell differentiation and embryonic developmentStage- and tissue-specific expression of the neu oncogene in rat development.Insertional mutagenesis identifies a member of the Wnt gene family as a candidate oncogene in the mammary epithelium of int-2/Fgf-3 transgenic miceDifferent effects of three polymorphisms in MicroRNAs on cancer risk in Asian population: evidence from published literatures.Isolation of the Xenopus homolog of int-1/wingless and expression during neurula stages of early development.Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouseMultiple RNAs expressed from the int-2 gene in mouse embryonal carcinoma cell lines encode a protein with homology to fibroblast growth factorsFour classes of mRNA are expressed from the mouse int-2 gene, a member of the FGF gene family.Secreted int-1 protein is associated with the cell surfaceThe Wnt-1 (int-1) oncogene promoter and its mechanism of activation by insertion of proviral DNA of the mouse mammary tumor virusMechanisms of endothelial growth control.Inducible overexpression and secretion of int-1 protein.Host genetic background effect on the frequency of mouse mammary tumor virus-induced rearrangements of the int-1 and int-2 loci in mouse mammary tumorsProviral insertions within the int-2 gene can generate multiple anomalous transcripts but leave the protein-coding domain intactDifferential regulation of the Wnt gene family during pregnancy and lactation suggests a role in postnatal development of the mammary glandExpression of the int-1 and int-2 loci in endogenous mouse mammary tumor virus-induced mammary tumorigenesis in the C3Hf mouse.Identification of protein products encoded by the proto-oncogene int-1The int-1 proto-oncogene products are glycoproteins that appear to enter the secretory pathway.Lessons Learned from Mouse Mammary Tumor Virus in Animal Models.Mutational analysis of mouse Wnt-1 identifies two temperature-sensitive alleles and attributes of Wnt-1 protein essential for transformation of a mammary cell lineBinary system for regulating transgene expression in mice: targeting int-2 gene expression with yeast GAL4/UAS control elements.
P2860
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P2860
Two proto-oncogenes implicated in mammary carcinogenesis, int-1 and int-2, are independently regulated during mouse development.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 1986
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Two proto-oncogenes implicated ...... ated during mouse development.
@en
Two proto-oncogenes implicated ...... ated during mouse development.
@nl
type
label
Two proto-oncogenes implicated ...... ated during mouse development.
@en
Two proto-oncogenes implicated ...... ated during mouse development.
@nl
prefLabel
Two proto-oncogenes implicated ...... ated during mouse development.
@en
Two proto-oncogenes implicated ...... ated during mouse development.
@nl
P2093
P2860
P356
P1476
Two proto-oncogenes implicated ...... ated during mouse development.
@en
P2093
Jakobovits A
Shackleford GM
P2860
P304
P356
10.1073/PNAS.83.20.7806
P407
P577
1986-10-01T00:00:00Z