Comparison of a chimeric anti-carcinoembryonic antigen antibody conjugated with visible or near-infrared fluorescent dyes for imaging pancreatic cancer in orthotopic nude mouse models.
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Development and Evaluation of a Fluorescent Antibody-Drug Conjugate for Molecular Imaging and Targeted Therapy of Pancreatic CancerPolyethylene glycol (PEG) linked to near infrared (NIR) dyes conjugated to chimeric anti-carcinoembryonic antigen (CEA) antibody enhances imaging of liver metastases in a nude-mouse model of human colon cancer.Advantages of fluorescence-guided laparoscopic surgery of pancreatic cancer labeled with fluorescent anti-carcinoembryonic antigen antibodies in an orthotopic mouse model.Specific tumor labeling enhanced by polyethylene glycol linkage of near infrared dyes conjugated to a chimeric anti-carcinoembryonic antigen antibody in a nude mouse model of human pancreatic cancerMetastatic recurrence in a pancreatic cancer patient derived orthotopic xenograft (PDOX) nude mouse model is inhibited by neoadjuvant chemotherapy in combination with fluorescence-guided surgery with an anti-CA 19-9-conjugated fluorophore.Fluorescence-guided surgery of retroperitoneal-implanted human fibrosarcoma in nude mice delays or eliminates tumor recurrence and increases survival compared to bright-light surgeryNear infra-red photoimmunotherapy with anti-CEA-IR700 results in extensive tumor lysis and a significant decrease in tumor burden in orthotopic mouse models of pancreatic cancer.MUC1 selectively targets human pancreatic cancer in orthotopic nude mouse models.Photoimmunotherapy lowers recurrence after pancreatic cancer surgery in orthotopic nude mouse models.Fluorescence-guided surgery, but not bright-light surgery, prevents local recurrence in a pancreatic cancer patient derived orthotopic xenograft (PDOX) model resistant to neoadjuvant chemotherapy (NAC)Fluorescent-Antibody Targeting of Insulin-Like Growth Factor-1 Receptor Visualizes Metastatic Human Colon Cancer in Orthotopic Mouse Models.Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse modelsIn vivo imaging with antibodies and engineered fragments.Current status and future perspectives of fluorescence-guided surgery for cancer.Application of infrared-based molecular imaging to a mouse model with head and neck cancer.Effective fluorescence-guided surgery of liver metastasis using a fluorescent anti-CEA antibody.Near-infrared-conjugated humanized anti-carcinoembryonic antigen antibody targets colon cancer in an orthotopic nude-mouse model.Tumor-Specific Labeling of Pancreatic Cancer Using a Humanized Anti-CEA Antibody Conjugated to a Near-Infrared Fluorophore.
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P2860
Comparison of a chimeric anti-carcinoembryonic antigen antibody conjugated with visible or near-infrared fluorescent dyes for imaging pancreatic cancer in orthotopic nude mouse models.
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article científic
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article scientifique
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bilimsel makale
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scientific article published on December 2013
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name
Comparison of a chimeric anti- ...... orthotopic nude mouse models.
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Comparison of a chimeric anti- ...... orthotopic nude mouse models.
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type
label
Comparison of a chimeric anti- ...... orthotopic nude mouse models.
@en
Comparison of a chimeric anti- ...... orthotopic nude mouse models.
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Comparison of a chimeric anti- ...... orthotopic nude mouse models.
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Comparison of a chimeric anti- ...... orthotopic nude mouse models.
@nl
P2093
P2860
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Comparison of a chimeric anti- ...... orthotopic nude mouse models.
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Ali A Maawy
George A Luiken
Michael Bouvet
Robert M Hoffman
Sharmeela Kaushal
Yukihiko Hiroshima
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P304
P356
10.1117/1.JBO.18.12.126016
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2013-12-01T00:00:00Z