Antibody-induced engagement of beta 2 integrins on adherent human neutrophils triggers activation of p21ras through tyrosine phosphorylation of the protooncogene product Vav
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Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrinsVav family proteins couple to diverse cell surface receptorsPRAM-1 is required for optimal integrin-dependent neutrophil functionSignalling pathways induced by protease-activated receptors and integrins in T cellsVav1: A Dr. Jekyll and Mr. Hyde protein--good for the hematopoietic system, bad for cancerMoving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytesIntegrin beta8 (ITGB8) activates VAV-RAC1 signaling via FAK in the acquisition of endometrial epithelial cell receptivity for blastocyst implantation.Vav3, a GEF for RhoA, Plays a Critical Role under High Glucose Conditions.Vav1 phosphorylation is induced by beta2 integrin engagement on natural killer cells upstream of actin cytoskeleton and lipid raft reorganization.Activated complement component 3 (C3) is required for ultraviolet induction of immunosuppression and antigenic toleranceSignaling via beta(2) integrins triggers neutrophil-dependent alteration in endothelial barrier function.αVβ3 Integrin Regulation of Respiratory Burst in Fibrinogen Adherent Human Neutrophils.ZAP-70 tyrosine kinase is required for LFA-1-dependent T cell migration.Signaling through the leukocyte integrin LFA-1 in T cells induces a transient activation of Rac-1 that is regulated by Vav and PI3K/Akt-1.Class I phosphoinositide-3-kinases and SRC kinases play a nonredundant role in regulation of adhesion-independent and -dependent neutrophil reactive oxygen species generation.Mac-1-dependent tyrosine phosphorylation during neutrophil adhesion.Cross-linking of beta2 integrins caused diminished responses of neutrophils to priming agents like lipopolysaccharide or tumor necrosis factor-alpha: possible involvement of tyrosine kinase Syk.Shigella invasion of macrophage requires the insertion of IpaC into the host plasma membrane. Functional analysis of IpaC.Down-regulation of Rac activity during beta 2 integrin-mediated adhesion of human neutrophils.Alternagin-C, a nonRGD-disintegrin, induces neutrophil migration via integrin signaling.Beta3 tyrosine phosphorylation and alphavbeta3-mediated adhesion are required for Vav1 association and Rho activation in leukocytes.Protein Kinase C Regulates Integrin-induced Activation of the Extracellular Regulated Kinase Pathway Upstream of Shc
P2860
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P2860
Antibody-induced engagement of beta 2 integrins on adherent human neutrophils triggers activation of p21ras through tyrosine phosphorylation of the protooncogene product Vav
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on August 1996
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Antibody-induced engagement of ...... the protooncogene product Vav
@en
Antibody-induced engagement of ...... the protooncogene product Vav.
@nl
type
label
Antibody-induced engagement of ...... the protooncogene product Vav
@en
Antibody-induced engagement of ...... the protooncogene product Vav.
@nl
prefLabel
Antibody-induced engagement of ...... the protooncogene product Vav
@en
Antibody-induced engagement of ...... the protooncogene product Vav.
@nl
P2860
P356
P1476
Antibody-induced engagement of ...... the protooncogene product Vav
@en
P2093
A Sjölander
J Eckerdal
P2860
P304
P356
10.1073/PNAS.93.16.8431
P407
P577
1996-08-01T00:00:00Z