Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1.
about
Neuronal Control of Adaptive ThermogenesisPhosphoinositides: Key modulators of energy metabolismTANK-binding kinase 1 (TBK1) modulates inflammatory hyperalgesia by regulating MAP kinases and NF-κB dependent genes.A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis.Transcriptional control and hormonal response of thermogenic fat.Genetic Ablation of CD38 Protects against Western Diet-Induced Exercise Intolerance and Metabolic Inflexibility.Inactivation of NF-κB p65 (RelA) in Liver Improves Insulin Sensitivity and Inhibits cAMP/PKA PathwayA novel thermoregulatory role for PDE10A in mouse and human adipocytesEndothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fatThe neuropeptide TLQP-21 opposes obesity via C3aR1-mediated enhancement of adrenergic-induced lipolysis.Leptin Resistance and the Neuro-Adipose Connection.Regulation of metabolism by the innate immune system.Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes.New therapeutic approaches for the treatment of obesity.Therapeutic potential of targeting TBK1 in autoimmune diseases and interferonopathies.Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal Degradation in Differentiated Adipocytes.Adapting to obesity with adipose tissue inflammation.The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists.Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing.TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue.Synthesized enone fatty acids resembling metabolites from gut microbiota suppress macrophage-mediated inflammation in adipocytes.Xanthoangelol and 4-hydroxyderrcin suppress obesity-induced inflammatory responses.Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKK and Reveal Mechanisms for Selective InhibitionInhibition of TBK1/IKKε Promotes Regeneration of Pancreatic β-cellsThe dipeptidyl peptidase-4 (DPP-4) inhibitor teneligliptin enhances brown adipose tissue function, thereby preventing obesity in miceRegulation of Energy Expenditure and Brown/Beige Thermogenic Activity by Interleukins: New Roles for Old Actors
P2860
Q26781425-68AC54B6-74F1-447D-A916-2EA42ED4EFE0Q27022953-7B58F3F7-F3E2-46F0-AAFB-706EF4D16E0BQ30652436-8CD4F35E-DECF-42D5-A05F-36BD44CABF2EQ35073277-AF2C8791-E8EE-4B89-AB7E-B7F86BBC9EAEQ35589477-1D77E5FE-67F3-4805-A1DA-2C6FE1D6BD02Q35749984-66E13C5A-6D50-49EE-8BFF-113A9D3518DBQ36104639-5CCA1C5D-D468-481F-952F-D4D203DB4F93Q37061111-108A6D94-1E02-4E47-92E6-52882DE94C3EQ37166149-DDBA6FC1-A0BE-426F-9EEB-22501ED82884Q37570982-454BB35D-4BDA-4230-BD9B-B3540E61B58CQ37681152-E44C43A8-7E64-452B-9CB1-1AEC82303946Q38629225-E051101F-F52D-42AF-831D-DCCCE4C7333BQ38690898-F2525EBE-FEDE-4AC7-94E9-3D6F150FBEFCQ38714562-D7F29503-1DD3-461D-A774-C7EBBC94282CQ38879970-B1BBB40A-ACEA-4325-B39E-063584909991Q39653875-51E77C5F-94A5-4A62-ABFB-086A6006EB53Q46611412-13439A03-3B50-4C06-8F49-F7E31D40E98EQ47576629-26173448-9E9F-4427-8196-2939977B071AQ49720453-481A4DEE-C359-46EF-BE51-B389B28FA136Q50098101-325972DE-5860-401C-AD2F-AA80509BC277Q50980091-CBFCA902-2C37-427B-8C66-990AC431C007Q51113272-3CF80C1F-681F-4D07-837C-F4476075CECAQ57143759-4F503472-79ED-44E2-B5C0-FAB6B55A9D43Q57805706-AC3AA340-9A85-4E37-BB96-27AC6B0A5627Q58553672-30FFBC2A-7CDB-4A6E-97A8-1779D548415FQ58692657-5496902A-1495-4E84-AAEA-9F83C1FFDFA8
P2860
Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 24 December 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Inflammation produces catechol ...... protein kinases IKKε and TBK1.
@en
Inflammation produces catechol ...... protein kinases IKKε and TBK1.
@nl
type
label
Inflammation produces catechol ...... protein kinases IKKε and TBK1.
@en
Inflammation produces catechol ...... protein kinases IKKε and TBK1.
@nl
prefLabel
Inflammation produces catechol ...... protein kinases IKKε and TBK1.
@en
Inflammation produces catechol ...... protein kinases IKKε and TBK1.
@nl
P2093
P2860
P356
P1433
P1476
Inflammation produces catechol ...... protein kinases IKKε and TBK1
@en
P2093
Jonathan Mowers
Joshua Simon
Louise Chang
Maeran Uhm
Shian-Huey Chiang
P2860
P304
P356
10.7554/ELIFE.01119
P407
P577
2013-12-24T00:00:00Z