Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2. - Wikidata - awgldk - TriplyDB

Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2.

Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2.

http://www.wikidata.org/entity/Q37407094

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Targeting the Mitotic Catastrophe Signaling Pathway in Cancer Caspase-2 as a tumour suppressor The PIDDosome, DNA-damage-induced apoptosis and beyond Non-Canonical Cell Death Induced by p53 BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer Chk1 inhibition in p53-deficient cell lines drives rapid chromosome fragmentation followed by caspase-independent cell death Nuclear Condensation during Mouse Erythropoiesis Requires Caspase-3-Mediated Nuclear Opening.Caspase-2-mediated cell death is required for deleting aneuploid cells.Caspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease.Role of caspase-3 cleaved IP3 R1 on Ca(2+) homeostasis and developmental competence of mouse oocytes and eggs Unfertilized frog eggs die by apoptosis following meiotic exit.Putative functions of caspase-2.Cdk1/cyclin B1 controls Fas-mediated apoptosis by regulating caspase-8 activity Unlaid Xenopus eggs degrade by apoptosis in the genital tract.Caspase activity is not required for the mitotic checkpoint or mitotic slippage in human cells.Killing cells by targeting mitosis Tumor-suppressing function of caspase-2 requires catalytic site Cys-320 and site Ser-139 in mice.A biotin switch-based proteomics approach identifies 14-3-3ζ as a target of Sirt1 in the metabolic regulation of caspase-2.Cyclin-dependent kinase-1 (Cdk1)/cyclin B1 dictates cell fate after mitotic arrest via phosphoregulation of antiapoptotic Bcl-2 proteins.Genetic deletion of caspase-2 accelerates MMTV/c-neu-driven mammary carcinogenesis in mice The role of caspase-2 in stress-induced apoptosis.Caspase-2 is essential for c-Jun transcriptional activation and Bim induction in neuron death.Analysis of the minimal specificity of caspase-2 and identification of Ac-VDTTD-AFC as a caspase-2-selective peptide substrate.Targeting the anaphase promoting complex: common pathways for viral infection and cancer therapy.Caspase-2: the orphan caspase.Cellular mechanisms controlling caspase activation and function.Evading apoptosis in cancer.Caspase-2: the reinvented enzyme.Cell Death Signaling.Caspase-2: an orphan enzyme out of the shadows.Cellular responses to a prolonged delay in mitosis are determined by a DNA damage response controlled by Bcl-2 family proteins.A novel Aurora kinase A inhibitor MK-8745 predicts TPX2 as a therapeutic biomarker in non-Hodgkin lymphoma cell lines.Sequential Cdk1 and Plk1 phosphorylation of caspase-8 triggers apoptotic cell death during mitosis Stalling in mitosis and releasing the apoptotic brake Sequential Cdk1 and Plk1 phosphorylation of protein tyrosine phosphatase 1B promotes mitotic cell death.ABT-737, a small molecule Bcl-2/Bcl-xL antagonist, increases antimitotic-mediated apoptosis in human prostate cancer cells A mitosis-sensing caspase activation platform? New insights into the PIDDosome.BimEL is phosphorylated at mitosis by Aurora A and targeted for degradation by βTrCP1.An Inhibitor of PIDDosome Formation.Bim vanishes in the light of a mitotic Aurora.

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Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2.

http://www.wikidata.org/entity/Q37407094

description

article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 03 September 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2.

@en

Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2.

@nl

type

label

Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2.

@en

Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2.

@nl

prefLabel

Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2.

@en

Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2.

@nl

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The EMBO Journal

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Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2

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Amanda B Parrish

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Carrie E Johnson

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Christopher D Freel

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J Will Thompson

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Jennifer L Day

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Joshua L Andersen

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Leta K Nutt

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M Arthur Moseley

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Sally Kornbluth

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P2860

The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress

Caspase-2: killer, savior and safeguard--emerging versatile roles for an ill-defined caspase

Caspase-2 activation in the absence of PIDDosome formation

Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint.

DNA-PKcs-PIDDosome: a nuclear caspase-2-activating complex with role in G2/M checkpoint maintenance

Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria

Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.

Mitochondrial dynamics and apoptosis

Post-cytochrome C protection from apoptosis conferred by a MAPK pathway in Xenopus egg extracts

Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression

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3216-3227

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scholarly article

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10.1038/EMBOJ.2009.253

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20

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28

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Marisa R Buchakjian

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2009-09-03T00:00:00Z

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26789554

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19730412

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apoptotic process

phosphorylation

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2771089

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