Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization. - Wikidata - awgldk - TriplyDB

Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization.

Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization.

http://www.wikidata.org/entity/Q37407596

about

NOS1AP modulates intracellular Ca(2+) in cardiac myocytes and is up-regulated in dystrophic cardiomyopathy RING finger protein RNF207, a novel regulator of cardiac excitation ZebraBeat: a flexible platform for the analysis of the cardiac rate in zebrafish embryos Optimisation of embryonic and larval ECG measurement in zebrafish for quantifying the effect of QT prolonging drugs Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association Sudden cardiac death prediction and prevention: report from a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop.The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion.The Popeye domain containing 2 (popdc2) gene in zebrafish is required for heart and skeletal muscle development.Congenital heart disease protein 5 associates with CASZ1 to maintain myocardial tissue integrity.Blebbistatin effectively uncouples the excitation-contraction process in zebrafish embryonic heart.Novel genes for QTc interval. How much heritability is explained, and how much is left to find?Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics.An enhancer polymorphism at the cardiomyocyte intercalated disc protein NOS1AP locus is a major regulator of the QT interval.The developing zebrafish (Danio rerio): a vertebrate model for high-throughput screening of chemical libraries.Systems pharmacology of arrhythmias Cardiac Arrhythmia: In vivo screening in the zebrafish to overcome complexity in drug discovery Simultaneous mapping of membrane voltage and calcium in zebrafish heart in vivo reveals chamber-specific developmental transitions in ionic currents.Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation.Drug-induced long QT syndrome Novel chemical suppressors of long QT syndrome identified by an in vivo functional screen.Genome-wide association studies of atrial fibrillation: past, present, and future.Pharmacogenomics: the genetics of variable drug responses.Electrocardiogram signals to assess zebrafish heart regeneration: implication of long QT intervals.Personalized medicine and the genotype-phenotype dilemma.Cardiovascular pharmacogenomics Adipose tissue gene expression and metabolic health of obese adults.Hooked! Modeling human disease in zebrafish.Generation of a cre recombinase-conditional Nos1ap over-expression transgenic mouse Pharmacogenetics of Potassium Channel Blockers.Mutation of wrb, a Component of the Guided Entry of Tail-Anchored Protein Pathway, Disrupts Photoreceptor Synapse Structure and Function.Quantifying cardiac functions in embryonic and adult zebrafish.Common genetic variants in sudden cardiac death.Using systems approaches to address challenges for clinical implementation of pharmacogenomics.The zebrafish model system in cardiovascular research: A tiny fish with mighty prospects.The zebrafish: scalable in vivo modeling for systems biology.A guide to analysis of cardiac phenotypes in the zebrafish embryo.Clinical considerations of heritable factors in common heart failure Optical mapping in the developing zebrafish heart.Zebrafish models in cardiac development and congenital heart birth defects.Recent advances in in vivo screening for antiarrhythmic drugs.

P2860

Q24292961-0E6B9722-DBEA-452E-BC48-14F3E238EAFB Q24305127-08573CC0-FBCE-4B37-950F-7ECD3239D4E9 Q27309211-753D9291-E4F9-4A91-B18E-7DC36E10103A Q27330065-E2FBB691-B255-4474-A2B9-15ADDF936633 Q30359686-F0FE018F-76C9-4556-A2E0-FCCF81CA1C06 Q30433543-7210757C-9FBB-4024-8902-D071CD12A2AA Q30502828-8F31D7AE-AAC9-4E98-9D83-698DD1990488 Q30540461-33137C8C-3D90-4352-9E42-2119F88B5968 Q30592648-FCC32533-F632-4699-9EFD-1CFD988DA7F6 Q33544983-95E19B6E-9E8D-4660-94DD-0C9232A6D724 Q33918840-A562E78E-7EDB-474D-9B6A-AB0512AF31C4 Q33983329-8473CC31-3E05-465C-BA96-8EC3E0BFA086 Q34000857-71B857AE-E695-4C2F-B92B-34E63BB3BC58 Q34024345-951B7DD7-30AA-4154-96E2-2139FC71CC80 Q34111154-2750D044-B268-4348-A37F-EAE968C06E52 Q34111355-2592EACE-02C2-4F3B-8888-30D05BD4DA1E Q34164184-1C9810C5-F9A0-4AF7-9DF6-2F02D5DBD772 Q34307746-5D24497E-F3A5-4F05-825B-2AE77EE4BD45 Q34358104-03294F90-8439-4355-9452-3F8DA8C75AC4 Q34462136-865779E3-A7A3-4C42-BF2E-0D39B8E5D7B5 Q34575300-2AB54AFD-2ACB-4676-A864-04E6B04D847D Q34976915-A5AB955D-B576-4D2F-9864-5BA36DFA025F Q35053225-67C12DA8-0922-473D-816C-4E522E54B979 Q35068864-B0A7DEE2-1ACD-48C2-AD61-B267B87E7BA8 Q35447163-6F4A2734-D6DB-4FC8-8FF5-93806F8095EC Q35577887-24419AF2-5818-4FCD-8C99-02778DF6B0A5 Q36068284-91DA73C6-693B-40F7-A729-004F480AA3C5 Q36851115-7D35A2AC-4B70-430F-937F-A8D1505E3858 Q36970927-87F6F8AE-8C32-4E34-8EE8-0761CE24DF47 Q36981670-67DAF9BE-A549-424B-A54D-F6FF49CDBB6B Q37146226-567BAAE1-4A53-4EC4-BB66-E2B65AB581A7 Q37418554-12B4B410-420D-4883-9A88-A2D00805BCA9 Q37621615-A82CD1B5-9006-46C4-AD07-5C6E392CE057 Q37659191-E1C82CD6-90C1-4AC4-B197-A2AE1C84F24F Q37794882-C0974D2F-33C3-4680-8B57-E051CEC7A784 Q37873094-B3EFA760-D455-44BA-B394-36A16D3D9CD8 Q37970334-95164F1F-4DB5-481B-8648-DB215D65EAC2 Q37998351-905BBD05-674A-43D6-AB5E-20B23CA990CB Q38019209-520CE7D2-47FF-44BB-BB05-A23D5B8296C5 Q38073317-65E0C2BC-E1EB-4F99-ABED-55FD082B8D1B

P2860

Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization.

http://www.wikidata.org/entity/Q37407596

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 03 August 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Drug-sensitized zebrafish scre ...... of myocardial repolarization.

@en

Drug-sensitized zebrafish scre ...... of myocardial repolarization.

@nl

type

label

Drug-sensitized zebrafish scre ...... of myocardial repolarization.

@en

Drug-sensitized zebrafish scre ...... of myocardial repolarization.

@nl

prefLabel

Drug-sensitized zebrafish scre ...... of myocardial repolarization.

@en

Drug-sensitized zebrafish scre ...... of myocardial repolarization.

@nl

P1433

Q37407596-3B7CEE14-67F0-4CC4-8BBD-20E665BB9CC6

P1476

Q37407596-05596A5B-DF3C-49F2-BA9E-5F2F796AD73B

P2093

Q37407596-2F25DCC9-0DE2-4649-ACE8-8BA2ADC715A3

Q37407596-3AA2288E-673F-4356-946B-13240379A0CF

Q37407596-4FA7300F-4D2B-454D-A219-D29521CB10AD

Q37407596-5EB5FEC0-1324-4F86-8CB9-1833B3BD2DBA

Q37407596-661EC722-0AFE-42B0-8E8A-CFFFB614176E

Q37407596-67FB260E-5CF1-49B6-9AE9-C3A6DA6C3665

Q37407596-759EB66A-853F-473F-9997-5090B3796BA4

Q37407596-79C727D3-4D6C-4FF5-BD1D-816C81E00F98

Q37407596-906BA27B-7FB8-453E-85D9-1A0A302BEC53

Q37407596-9C37C934-E325-4A7A-86B2-5445B58285E9

P2860

Q37407596-03C292AF-F350-47D3-A557-3F8CCCD0A599

Q37407596-05FCA1DE-5A21-44D0-9229-035EC2CA8058

Q37407596-0650B3E7-86AD-4335-B5DB-BF9480D085A6

Q37407596-0F123CC4-405E-4257-BDBE-7A7367D0BDE6

Q37407596-208F9206-BF60-41E4-867D-B1FA97F61641

Q37407596-224611B9-97B3-42DB-9971-9F2FC0469797

Q37407596-2EC1D771-C92E-47AB-BEFC-A946AB26880A

Q37407596-2ED44F9F-C199-416D-BC7E-553C5FC4E149

Q37407596-374D5CD9-B3E8-4DE2-BA99-AE0A8B29CD16

Q37407596-48E05EC2-9412-44BA-B24E-C4D1C99493BB

P304

Q37407596-AAFC2A79-40D0-4866-8A7F-5DFCE66F01E1

P31

Q37407596-18666349-E662-4AE9-AF06-315EE1E9292D

P356

Q37407596-71535DC0-3D5D-4E6D-8F47-30895751EDCB

P407

Q37407596-F0298BF5-FB10-4EF5-A1D0-C591204C7A52

P433

Q37407596-DCD95985-363D-4998-8C01-ABD2A453EFB1

P478

Q37407596-24D1334D-55E0-41BD-A268-410BDE4BDA9B

P50

Q37407596-9AD5CC87-1D9E-4721-B853-5962CC2A497C

Q37407596-9E4A8763-620C-46F4-AC9F-45CF31F8FC51

P577

Q37407596-3F19B1E4-BE97-4D8D-B1EF-6142BB9D70C4

P5875

Q37407596-4B66163B-ED3D-41E5-A765-C24F7F83CE29

P698

Q37407596-6859C0F4-07E2-4772-B426-DDF564B10099

P921

Q37407596-40769BF4-9397-4E38-9361-37544C425C76

P932

Q37407596-03FE5EF2-EBFD-43F5-8E60-F136A776512D

P356

CIRCULATIONAHA.108.821082

P1433

P1476

Drug-sensitized zebrafish scre ...... of myocardial repolarization.

@en

P2093

Adam H Amsterdam

http://www.w3.org/2001/XMLSchema#string

Aravinda Chakravarti

http://www.w3.org/2001/XMLSchema#string

Arne Pfeufer

http://www.w3.org/2001/XMLSchema#string

Calum A MacRae

http://www.w3.org/2001/XMLSchema#string

Dan E Arking

http://www.w3.org/2001/XMLSchema#string

Dan M Roden

http://www.w3.org/2001/XMLSchema#string

David J Milan

http://www.w3.org/2001/XMLSchema#string

David S Rosenbaum

http://www.w3.org/2001/XMLSchema#string

Ian L Jones

http://www.w3.org/2001/XMLSchema#string

Jeffrey R Winterfield

http://www.w3.org/2001/XMLSchema#string

P2860

Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death

Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome

CAPON modulates cardiac repolarization via neuronal nitric oxide synthase signaling in the heart

Variations in DNA elucidate molecular networks that cause disease

Zebrafish model for human long QT syndrome

Long QT syndrome in neonates: conduction disorders associated with HERG mutations and sinus bradycardia with KCNQ1 mutations.

Drug-induced prolongation of the QT interval.

Association of long QT syndrome loci and cardiac events among patients treated with beta-blockers.

Identification of 315 genes essential for early zebrafish development.

Molecular and cellular mechanisms of cardiac arrhythmias.

P304

553-559

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1161/CIRCULATIONAHA.108.821082

http://www.w3.org/2001/XMLSchema#string

P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

120

http://www.w3.org/2001/XMLSchema#string

P50

P577

2009-08-03T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

26714373

http://www.w3.org/2001/XMLSchema#string

P698

19652097

http://www.w3.org/2001/XMLSchema#string

P921

P932

2771327

http://www.w3.org/2001/XMLSchema#string