The comet assay: a sensitive method for detecting DNA damage in individual cells.
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Cytotoxicity and genotoxicity of coronaridine from Tabernaemontana catharinensis A.DC in a human laryngeal epithelial carcinoma cell line (Hep-2)A comprehensive review on clinical applications of comet assayNovel amphiphilic cationic porphyrin and its Ag(II) complex as potential anticancer agents.SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair.DNA phosphorothioate modifications influence the global transcriptional response and protect DNA from double-stranded breaks.L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability.Fluctuation of "sperm DNA integrity" in accordance with semen parameters, and it's relationship with infertility.An investigation into the association between DNA damage and dietary fatty acid in men with prostate cancer.DNA damage in blood cells exposed to low-level lasers.Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks.Assessment of cytotoxicity and genotoxicity of stem bark extracts from Canarium odontophyllum Miq. (dabai) against HCT 116 human colorectal cancer cell line.Genotoxic effects of Tabebuia impetiginosa (Mart. Ex DC.) Standl. (Lamiales, Bignoniaceae) extract in Wistar ratsYAP activation protects urothelial cell carcinoma from treatment-induced DNA damage.Genotoxicity of styrene-acrylonitrile trimer in brain, liver, and blood cells of weanling F344 rats.DNA damage in normally and prematurely aged mice.Methanolic extract of Anthocephalus cadamba induces apoptosis in Ehrlich ascites carcinoma cells in experimental miceIn benign Barrett's epithelial cells, acid exposure generates reactive oxygen species that cause DNA double-strand breaks.Antiproliferative Activity and Apoptosis Inducing Mechanism of Anthocephalus cadamba on Dalton's Lymphoma Ascites Cells.Vitamin C modulates DNA damage induced by hydrogen peroxide in human colorectal adenocarcinoma cell lines (HT29) estimated by comet assay in vitro.Evidence of Some Natural Products with Antigenotoxic Effects. Part 1: Fruits and Polysaccharides.RNF20-RNF40: A ubiquitin-driven link between gene expression and the DNA damage response.Application of the comet assay method in clinical studies.A single-molecule assessment of the protective effect of DMSO against DNA double-strand breaks induced by photo-and γ-ray-irradiation, and freezingCombinations of genotoxic tests for the evaluation of group 1 IARC carcinogens.Visualization and quantitative analysis of extrachromosomal telomere-repeat DNA in individual human cells by Halo-FISH.Antiproliferative and apoptosis-inducing activity of an oxidovanadium(IV) complex with the flavonoid silibinin against osteosarcoma cells.DNA fragmentation induced by all-trans retinoic acid and its steroidal analogue EA-4 in C2 C12 mouse and HL-60 human leukemic cells in vitro.Antitumor properties of a vanadyl(IV) complex with the flavonoid chrysin [VO(chrysin)2EtOH]2 in a human osteosarcoma model: the role of oxidative stress and apoptosis.Oxidative DNA damage is involved in ochratoxin A-induced G2 arrest through ataxia telangiectasia-mutated (ATM) pathways in human gastric epithelium GES-1 cells in vitro.The modulatory effect of melatonin on genotoxicity of irinotecan in healthy human lymphocytes and cancer cells.Hydroxylamido-amino acid complexes of oxovanadium(V). Toxicological study in cell culture and in a zebrafish model.Cyto- and genotoxicity of a vanadyl(IV) complex with oxodiacetate in human colon adenocarcinoma (Caco-2) cells: potential use in cancer therapy.Biocompatibility of magnesium particles evaluated by in vitro cytotoxicity and genotoxicity assays.Impact of polyphenol metabolites produced by colonic microbiota on expression of COX-2 and GSTT2 in human colon cells (LT97).Study of cytotoxic and therapeutic effects of stable and purified silver nanoparticles on tumor cells.Baf60b-mediated ATM-p53 activation blocks cell identity conversion by sensing chromatin opening.G9a coordinates with the RPA complex to promote DNA damage repair and cell survival.Calcium influx-mediated translocation of m-calpain induces Ku80 cleavage and enhances the Ku80-related DNA repair pathway.A novel acridine derivative, LS-1-10 inhibits autophagic degradation and triggers apoptosis in colon cancer cells.Interrogation of nucleotide excision repair capacity: impact on platinum-based cancer therapy.
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The comet assay: a sensitive method for detecting DNA damage in individual cells.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 06 March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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The comet assay: a sensitive method for detecting DNA damage in individual cells.
@en
The comet assay: a sensitive method for detecting DNA damage in individual cells.
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The comet assay: a sensitive method for detecting DNA damage in individual cells.
@en
The comet assay: a sensitive method for detecting DNA damage in individual cells.
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The comet assay: a sensitive method for detecting DNA damage in individual cells.
@en
The comet assay: a sensitive method for detecting DNA damage in individual cells.
@nl
P2093
P1433
P1476
The comet assay: a sensitive method for detecting DNA damage in individual cells.
@en
P2093
Michael A McNutt
Wei-Guo Zhu
Wenjuan Liao
P356
10.1016/J.YMETH.2009.02.016
P577
2009-03-06T00:00:00Z