Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway.
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Obstetrical antiphospholipid syndrome: from the pathogenesis to the clinical and therapeutic implicationsAntiphospholipid antibodies and the placenta: a systematic review of their in vitro effects and modulation by treatmentInnate immunity, decidual cells, and preeclampsiaDAMPening inflammation by modulating TLR signalling.Toll-like receptors at the maternal-fetal interface in normal pregnancy and pregnancy disorders.Schistosoma japonicum soluble egg antigens attenuate invasion in a first trimester human placental trophoblast modelA role for uric acid and the Nalp3 inflammasome in antiphospholipid antibody-induced IL-1β production by human first trimester trophoblast.Pathophysiology of the antiphospholipid antibody syndrome.Aspirin and heparin effect on basal and antiphospholipid antibody modulation of trophoblast function.Purified IgG from patients with obstetric but not IgG from non-obstetric antiphospholipid syndrome inhibit trophoblast invasion.Interaction of β2-glycoprotein I with lipopolysaccharide leads to Toll-like receptor 4 (TLR4)-dependent activation of macrophages.Viral single stranded RNA induces a trophoblast pro-inflammatory and antiviral response in a TLR8-dependent and -independent mannerAntiphospholipid Syndrome during pregnancy: the state of the artPrevention of Defective Placentation and Pregnancy Loss by Blocking Innate Immune Pathways in a Syngeneic Model of Placental Insufficiency.Oxidative damage, inflammation, and Toll-like receptor 4 pathway are increased in preeclamptic patients: a case-control study.Lipopolysaccharide appears to activate human endometrial endothelial cells through TLR-4-dependent and TLR-4-independent mechanismsNod1, but not the ASC inflammasome, contributes to induction of IL-1β secretion in human trophoblasts after sensing of Chlamydia trachomatisApoE Receptor 2 Mediation of Trophoblast Dysfunction and Pregnancy Complications Induced by Antiphospholipid Antibodies in MiceSchistosome egg antigens elicit a proinflammatory response by trophoblast cells of the human placentaPathophysiological mechanisms in antiphospholipid syndromeAnticoagulation in management of antiphospholipid antibody syndrome in pregnancy.Antiphospholipid antibody-induced miR-146a-3p drives trophoblast interleukin-8 secretion through activation of Toll-like receptor 8.Aspirin: The Mechanism of Action Revisited in the Context of Pregnancy Complications.Recurrent miscarriage and autoimmunity.Pathogenesis of antiphospholipid syndrome: understanding the antibodies.Intrinsic danger: activation of Toll-like receptors in rheumatoid arthritis.Potential use of statins in the treatment of antiphospholipid syndrome.Management of women with recurrent pregnancy losses and antiphospholipid antibody syndrome.Damage-associated molecular patterns and their receptors in upper airway pathologies.Anti-β2-glycoprotein I antibodies.The role of TLR4 in pathophysiology of antiphospholipid syndrome-associated thrombosis and pregnancy morbidity.The journey of antiphospholipid antibodies from cellular activation to antiphospholipid syndrome.Antiphospholipid syndrome: an update.Targeting danger-associated molecular patterns after myocardial infarction.Do adverse pregnancy outcomes contribute to accelerated cardiovascular events seen in young women with systemic lupus erythematosus?Clinical Risk Assessment in the Antiphospholipid Syndrome: Current Landscape and Emerging Biomarkers.Vitamin D and autoimmunity.Aspirin-triggered lipoxin prevents antiphospholipid antibody effects on human trophoblast migration and endothelial cell interactions.Vitamin D reverses aPL-induced inflammation and LMWH-induced sFlt-1 release by human trophoblast.Hydroxychloroquine restores trophoblast fusion affected by antiphospholipid antibodies.
P2860
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P2860
Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Antiphospholipid antibodies in ...... st via the TLR4/MyD88 pathway.
@en
Antiphospholipid antibodies in ...... st via the TLR4/MyD88 pathway.
@nl
type
label
Antiphospholipid antibodies in ...... st via the TLR4/MyD88 pathway.
@en
Antiphospholipid antibodies in ...... st via the TLR4/MyD88 pathway.
@nl
prefLabel
Antiphospholipid antibodies in ...... st via the TLR4/MyD88 pathway.
@en
Antiphospholipid antibodies in ...... st via the TLR4/MyD88 pathway.
@nl
P2093
P2860
P921
P1476
Antiphospholipid antibodies in ...... st via the TLR4/MyD88 pathway.
@en
P2093
Anisur Rahman
Britta Panda
Charis Pericleous
Jan J Brosens
Larry W Chamley
Melissa J Mulla
Michael J Paidas
Shawna K Joyce
Vikki M Abrahams
P2860
P304
P356
10.1111/J.1600-0897.2009.00717.X
P577
2009-08-01T00:00:00Z