Desnutrin/ATGL activates PPARδ to promote mitochondrial function for insulin secretion in islet β cells
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Comparative gene identification-58/α/β hydrolase domain 5: more than just an adipose triglyceride lipase activator?Perilipins 2 and 3 lack a carboxy-terminal domain present in perilipin 1 involved in sequestering ABHD5 and suppressing basal lipolysis.Perilipin 5 regulates islet lipid metabolism and insulin secretion in a cAMP-dependent manner: implication of its role in the postprandial insulin secretion.PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation.Integrative and systemic approaches for evaluating PPARβ/δ (PPARD) function.Calcium-independent phospholipases A2 and their roles in biological processes and diseases.Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation.PGC-1 coactivators in β-cells regulate lipid metabolism and are essential for insulin secretion coupled to fatty acidsHypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity.ERRγ Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive β CellsPPAR-delta promotes survival of breast cancer cells in harsh metabolic conditionsLipid disequilibrium disrupts ER proteostasis by impairing ERAD substrate glycan trimming and dislocation.Long- but not short-term adult-onset, isolated GH deficiency in male mice leads to deterioration of β-cell function, which cannot be accounted for by changes in β-cell mass.Integrated Regulation of Hepatic Lipid and Glucose Metabolism by Adipose Triacylglycerol Lipase and FoxO Proteins.FAT FLUX: enzymes, regulators, and pathophysiology of intracellular lipolysis.Lipolysis and lipases in white adipose tissue - An update.Diacylglycerol acyltransferase 2 links glucose utilization to fatty acid oxidation in the brown adipocytes.Mechanisms of β-cell functional adaptation to changes in workloadDistinct but complementary contributions of PPAR isotypes to energy homeostasis.IL-15 Mediates Mitochondrial Activity through a PPARδ-Dependent-PPARα-Independent Mechanism in Skeletal Muscle Cells.Establishing the lipid droplet proteome: Mechanisms of lipid droplet protein targeting and degradation.Transcribing β-cell mitochondria in health and disease.AMPK Phosphorylates Desnutrin/ATGL and Hormone-Sensitive Lipase To Regulate Lipolysis and Fatty Acid Oxidation within Adipose Tissue.Mouse insulin cells expressing an inducible RIPCre transgene are functionally impaired.Intracellular free fatty acid upholds β-cell glucose competence: The role of peroxisome proliferator-activated receptor δ and mitochondrial metabolism.A beta cell ATGL-lipolysis/adipose tissue axis controls energy homeostasis and body weight via insulin secretion in mice.Role of Hormone-sensitive Lipase in Leptin-Promoted Fat Loss and Glucose Lowering.Lipoquality control by phospholipase A2 enzymes.Cold-Induced Thermogenesis Depends on ATGL-Mediated Lipolysis in Cardiac Muscle, but Not Brown Adipose Tissue.cTAGE5 deletion in pancreatic β cells impairs proinsulin trafficking and insulin biogenesis in mice.Cytosolic lipolysis and lipophagy: two sides of the same coin.The selective peroxisome proliferator-activated receptor-delta agonist seladelpar reverses nonalcoholic steatohepatitis pathology by abrogating lipotoxicity in diabetic obese mice.Hints on ATGL implications in cancer: beyond bioenergetic clues.PPARβ/δ: A Key Therapeutic Target in Metabolic Disorders.
P2860
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P2860
Desnutrin/ATGL activates PPARδ to promote mitochondrial function for insulin secretion in islet β cells
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
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2013年學術文章
@zh-hant
name
Desnutrin/ATGL activates PPARδ ...... lin secretion in islet β cells
@en
Desnutrin/ATGL activates PPARδ ...... in secretion in islet β cells.
@nl
type
label
Desnutrin/ATGL activates PPARδ ...... lin secretion in islet β cells
@en
Desnutrin/ATGL activates PPARδ ...... in secretion in islet β cells.
@nl
prefLabel
Desnutrin/ATGL activates PPARδ ...... lin secretion in islet β cells
@en
Desnutrin/ATGL activates PPARδ ...... in secretion in islet β cells.
@nl
P2093
P2860
P1433
P1476
Desnutrin/ATGL activates PPARδ ...... lin secretion in islet β cells
@en
P2093
Andressa B Lopes
Hei Sook Sul
Marcia J Abbott
Maryam Ahmadian
Tianyi Tang
Yuhui Wang
P2860
P304
P356
10.1016/J.CMET.2013.10.012
P577
2013-11-21T00:00:00Z