Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-β to promote proliferation.
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Disruptive chemicals, senescence and immortalityTCGA data and patient-derived orthotopic xenografts highlight pancreatic cancer-associated angiogenesisEpithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer.Vicious cycle of TGF-β signaling in tumor progression and metastasis.Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression.A pilot study to develop a diagnostic test for pancreatic ductal adenocarcinoma based on differential expression of select miRNA in plasma and bile.Notch signaling induces epithelial-mesenchymal transition to promote invasion and metastasis in adenoid cystic carcinoma.The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinomaIntegrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinomaBAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages.MiR-744 increases tumorigenicity of pancreatic cancer by activating Wnt/β-catenin pathway.Angiogenic gene signature in human pancreatic cancer correlates with TGF-beta and inflammatory transcriptomes.Mysteries of TGF-β Paradox in Benign and Malignant Cells.SMAD7: a timer of tumor progression targeting TGF-β signaling.Clinical significance of epithelial-mesenchymal transition.The conflicting roles of tumor stroma in pancreatic cancer and their contribution to the failure of clinical trials: a systematic review and critical appraisal.Down-regulation of human endogenous retrovirus type K (HERV-K) viral env RNA in pancreatic cancer cells decreases cell proliferation and tumor growth.TGFβ promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1.The pancreatic cancer microenvironment: A true double agent.Combined targeting of TGF-β, EGFR and HER2 suppresses lymphangiogenesis and metastasis in a pancreatic cancer model.Inactivation of TGFβ receptor II signalling in pancreatic epithelial cells promotes acinar cell proliferation, acinar-to-ductal metaplasia and fibrosis during pancreatitis.TGF-β1 pathway affects the protein expression of many signaling pathways, markers of liver cancer stem cells, cytokeratins, and TERT in liver cancer HepG2 cells.TGF-β1 signaling pathway serves a role in HepG2 cell regulation by affecting the protein expression of PCNA, gankyrin, p115, XIAP and survivinRelA: a tale of a stitch in time.Expression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancerTGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate TumorigenesisTransgelin mediates transforming growth factor-β1-induced proliferation of human periodontal ligament cells.Notch signaling via regulation of RB and p-AKT but not PIK3CG contributes to MIA PaCa-2 cell growth and migration to affect pancreatic carcinogenesis.
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Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-β to promote proliferation.
description
article científic
@ca
article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 16 December 2013
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Pancreatic cancer-associated r ...... GF-β to promote proliferation.
@en
Pancreatic cancer-associated r ...... GF-β to promote proliferation.
@nl
type
label
Pancreatic cancer-associated r ...... GF-β to promote proliferation.
@en
Pancreatic cancer-associated r ...... GF-β to promote proliferation.
@nl
prefLabel
Pancreatic cancer-associated r ...... GF-β to promote proliferation.
@en
Pancreatic cancer-associated r ...... GF-β to promote proliferation.
@nl
P2093
P2860
P356
P1476
Pancreatic cancer-associated r ...... TGF-β to promote proliferation
@en
P2093
A Jesse Gore
Lakshmi Reddy Palam
Murray Korc
Samantha L Deitz
P2860
P304
P356
10.1172/JCI71526
P407
P50
P577
2013-12-16T00:00:00Z