Development and preclinical testing of a high-affinity single-chain antibody against (+)-methamphetamine
about
Customizing monoclonal antibodies for the treatment of methamphetamine abuse: current and future applicationsCrystal structures of a therapeutic single chain antibody in complex with two drugs of abuse-Methamphetamine and 3,4-methylenedioxymethamphetamineAffinity improvement of a therapeutic antibody to methamphetamine and amphetamine through structure-based antibody engineeringStructural characterization of a therapeutic anti-methamphetamine antibody fragment: oligomerization and binding of active metabolitesThe synthesis of haptens and their use for the development of monoclonal antibodies for treating methamphetamine abuse.Therapeutic anti-methamphetamine antibody fragment-nanoparticle conjugates: synthesis and in vitro characterization.The fate and function of therapeutic antiaddiction monoclonal antibodies across the reproductive cycle of rats.Immunopharmacotherapeutic manifolds and modulation of cocaine overdose.Insights into scFv:drug binding using the molecular dynamics simulation and free energy calculation.A Nanotechnology-Based Platform for Extending the Pharmacokinetic and Binding Properties of Anti-methamphetamine Antibody Fragments.An antidote for acute cocaine toxicity.Vaccination protects rats from methamphetamine-induced impairment of behavioral responding for food.Designing immunotherapies to thwart drug abuse.Development of active and passive human vaccines to treat methamphetamine addiction.Anti-drug vaccines to treat substance abuse.Recombinant Adeno-Associated Virus-Mediated Expression of Methamphetamine Antibody Attenuates Methamphetamine-Induced Hyperactivity in Mice.In silico experiments of single-chain antibody fragment against drugs of abuse.PEGylation of a High-Affinity Anti-(+)Methamphetamine Single Chain Antibody Fragment Extends Functional Half-Life by Reducing Clearance.Development and testing of AAV-delivered single-chain variable fragments for the treatment of methamphetamine abuse.
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P2860
Development and preclinical testing of a high-affinity single-chain antibody against (+)-methamphetamine
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 11 January 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Development and preclinical te ...... dy against (+)-methamphetamine
@en
Development and preclinical testing of a high-affinity single-chain antibody against
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type
label
Development and preclinical te ...... dy against (+)-methamphetamine
@en
Development and preclinical testing of a high-affinity single-chain antibody against
@nl
prefLabel
Development and preclinical te ...... dy against (+)-methamphetamine
@en
Development and preclinical testing of a high-affinity single-chain antibody against
@nl
P2093
P2860
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P1476
Development and preclinical te ...... dy against (+)-methamphetamine
@en
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Elizabeth M Laurenzana
Eric C Peterson
Howard P Hendrickson
S Michael Owens
William T Atchley
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P304
P356
10.1124/JPET.107.134395
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P577
2008-01-11T00:00:00Z