A monoclonal IgG anticardiolipin antibody from a patient with the antiphospholipid syndrome is thrombogenic in mice
about
The epitopes for some antiphospholipid antibodies are adducts of oxidized phospholipid and beta2 glycoprotein 1 (and other proteins)Prevention of experimental antiphospholipid syndrome and endothelial cell activation by synthetic peptides.Anti-prothrombin antibodies cause thrombosis in a novel qualitative ex-vivo animal model.Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infectionβ₂-Glycoprotein-1 autoantibodies from patients with antiphospholipid syndrome are sufficient to potentiate arterial thrombus formation in a mouse model.Human monoclonal antiphospholipid antibodies disrupt the annexin A5 anticoagulant crystal shield on phospholipid bilayers: evidence from atomic force microscopy and functional assay.Some antiphospholipid antibodies recognize conformational epitopes shared by beta2-glycoprotein I and the homologous catalytic domains of several serine proteases.Antiphospholipid antibodies: laboratory and pathogenetic aspects.Antiphospholipid antibodies: effects on trophoblast and endothelial cells.Some antiphospholipid antibodies bind to hemostasis and fibrinolysis proteases and promote thrombosis.Plasmin immunization preferentially induces potentially prothrombotic IgG anticardiolipin antibodies in MRL/MpJ mice.In vivo models of thrombosis for the antiphospholipid syndrome.Antiphospholipid antibodies and cerebral lupus.Characterization of IgG monoclonal anti-cardiolipin/anti-beta2GP1 antibodies from two patients with antiphospholipid syndrome reveals three species of antibodies.An IgG antiprothrombin antibody enhances prothrombin binding to damaged endothelial cells and shortens plasma coagulation times.Reactivity profiles of broadly neutralizing anti-HIV-1 antibodies are distinct from those of pathogenic autoantibodies.True anti-anionic phospholipid immunoglobulin M antibodies can exert lupus anticoagulant activity.Intrauterine fetal death in mice caused by cytomegalovirus-derived peptide induced aPL antibodies.Antiphospholipid antibody-mediated effects in an arterial model of thrombosis are dependent on Toll-like receptor 4.Antibodies against lysophosphatidylcholine and oxidized LDL in patients with SLEEnhanced monocyte expression of tissue factor by oxidative stress in patients with antiphospholipid antibodies: effect of antioxidant treatment
P2860
Q28379106-34F2117E-9B14-4A84-B04B-A29D23FA021DQ30676844-D9B59AA0-CAAC-404A-BC5F-A74CE124D850Q33348155-8C6558DC-43AE-4043-A433-78ADD1CB3227Q33479167-DFABE8F7-A2E8-43F5-BB6C-8A9735815369Q33796355-AC149A9D-EE89-43AC-8357-02485CCEB49BQ35792021-623D3EB4-7F58-4E0A-BCC4-0F5F601CDBCFQ35945526-0C1BADC9-4BE7-40B5-B50F-3F0ABC8C251DQ36799474-937CFECF-50BD-4558-A5F2-754EF262BD3FQ36881604-8F2A8102-42DA-4FFA-8DB2-9D9297474A16Q37283026-04B6E693-8B4F-4CD8-A3B1-989E8C4ADC60Q37416062-AB4C6417-3E44-4F27-A08C-A3F1EAB8A4E8Q41197483-43878CB2-FC7F-46A4-A318-41B3356F9A57Q41590581-305FC836-CA22-4043-B985-89FC4EDEC4F3Q41650589-89802F5F-A605-4EBF-B215-1C81B6BB347FQ41696730-D07898B0-7C14-4D54-BDBD-B022D45C2D88Q42132261-A31397D8-F8FB-4932-A57A-2584E668D235Q43910570-0DBF52E2-15DF-4D97-A303-61D33E12C503Q45077755-ECAACD66-6969-44A0-998C-61661177D2FBQ48074369-334B4816-6558-4470-B539-B8AC1D5A9978Q58190403-A1DFC6C2-D580-4A78-9686-07A2F70F5DAEQ58421151-D355721D-593A-42F4-8734-71DCB0F67210
P2860
A monoclonal IgG anticardiolipin antibody from a patient with the antiphospholipid syndrome is thrombogenic in mice
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A monoclonal IgG anticardiolip ...... ndrome is thrombogenic in mice
@en
A monoclonal IgG anticardiolip ...... drome is thrombogenic in mice.
@nl
type
label
A monoclonal IgG anticardiolip ...... ndrome is thrombogenic in mice
@en
A monoclonal IgG anticardiolip ...... drome is thrombogenic in mice.
@nl
prefLabel
A monoclonal IgG anticardiolip ...... ndrome is thrombogenic in mice
@en
A monoclonal IgG anticardiolip ...... drome is thrombogenic in mice.
@nl
P2093
P2860
P356
P1476
A monoclonal IgG anticardiolip ...... ndrome is thrombogenic in mice
@en
P2093
H H Handley
S S Pierangeli
P2860
P304
P356
10.1073/PNAS.93.16.8606
P407
P577
1996-08-01T00:00:00Z