Cholesterol-dependent cytolysins induce rapid release of mature IL-1beta from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner - Wikidata - awgldk - TriplyDB

Cholesterol-dependent cytolysins induce rapid release of mature IL-1beta from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner

Cholesterol-dependent cytolysins induce rapid release of mature IL-1beta from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner

http://www.wikidata.org/entity/Q37415517

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Bacterial Exotoxins and the Inflammasome More than a pore: the cellular response to cholesterol-dependent cytolysins Initiation and perpetuation of NLRP3 inflammasome activation and assembly Calcium signaling and mitochondrial destabilization in the triggering of the NLRP3 inflammasome Mitochondria: diversity in the regulation of the NLRP3 inflammasome.The inflammasome NLRs in immunity, inflammation, and associated diseases Inflammasome activation and IL-1β/IL-18 processing are influenced by distinct pathways in microglia Effect of enterohaemorrhagic Escherichia coli O157:H7-specific enterohaemolysin on interleukin-1β production differs between human and mouse macrophages due to the different sensitivity of NLRP3 activation.Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.Listeriolysin O-dependent bacterial entry into the cytoplasm is required for calpain activation and interleukin-1 alpha secretion in macrophages infected with Listeria monocytogenes Differential role of pannexin-1/ATP/P2X7 axis in IL-1β release by human monocytes.Activation of macrophages by P2X7-induced microvesicles from myeloid cells is mediated by phospholipids and is partially dependent on TLR4.TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection Activation and measurement of NLRP3 inflammasome activity using IL-1β in human monocyte-derived dendritic cells An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection.Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells NLRP3 inflammasome is a target for development of broad-spectrum anti-infective drugs U1-small nuclear ribonucleoprotein activates the NLRP3 inflammasome in human monocytes Critical role for calcium mobilization in activation of the NLRP3 inflammasome.Sensing and reacting to microbes through the inflammasomes.Reduction of streptolysin O (SLO) pore-forming activity enhances inflammasome activation.Targeting the unfolded protein response, XBP1, and the NLRP3 inflammasome in fibrosis and cancer Macrophage responses to bacterial toxins: a balance between activation and suppression.Recognition of bacterial infection by innate immune sensors.Mechanism and Regulation of NLRP3 Inflammasome Activation.Coordinate stimulation of macrophages by microparticles and TLR ligands induces foam cell formation Cholesterol and nonalcoholic fatty liver disease: renewed focus on an old villain.IL-18 triggered by the Nlrp3 inflammasome induces host innate resistance in a pulmonary model of fungal infection.Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation.Multiple Cathepsins Promote Pro-IL-1β Synthesis and NLRP3-Mediated IL-1β Activation Cholesterol-dependent cytolysins impair pro-inflammatory macrophage responses.The inflammasome activating caspase 1 mediates fibrosis and myofibroblast differentiation in systemic sclerosis

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P2860

Cholesterol-dependent cytolysins induce rapid release of mature IL-1beta from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner

http://www.wikidata.org/entity/Q37415517

description

article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 12 August 2009

@en

vedecký článok

@sk

vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

Cholesterol-dependent cytolysi ...... d cathepsin B-dependent manner

@en

Cholesterol-dependent cytolysi ...... cathepsin B-dependent manner.

@nl

type

label

Cholesterol-dependent cytolysi ...... d cathepsin B-dependent manner

@en

Cholesterol-dependent cytolysi ...... cathepsin B-dependent manner.

@nl

prefLabel

Cholesterol-dependent cytolysi ...... d cathepsin B-dependent manner

@en

Cholesterol-dependent cytolysi ...... cathepsin B-dependent manner.

@nl

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Journal of Leukocyte Biology

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Cholesterol-dependent cytolysi ...... d cathepsin B-dependent manner

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P2093

Gabriel Núñez

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L Michael Thomas

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Luigi Franchi

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Russell D Salter

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Simon C Watkins

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P2860

Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Purification, characterization, and toxicity of the sulfhydryl-activated hemolysin listeriolysin O from Listeria monocytogenes

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

Gout-associated uric acid crystals activate the NALP3 inflammasome

Cryopyrin activates the inflammasome in response to toxins and ATP

The Bacillus anthracis cholesterol-dependent cytolysin, Anthrolysin O, kills human neutrophils, monocytes and macrophages

Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages

Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

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1227-1238

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scholarly article

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10.1189/JLB.0309164

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5

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86

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26736603

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19675207

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2774880

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