Influenza virus M2 protein inhibits epithelial sodium channels by increasing reactive oxygen species.
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Relevance of Viroporin Ion Channel Activity on Viral Replication and PathogenesisHost gene targets for novel influenza therapies elucidated by high-throughput RNA interference screensNano-TiO₂ particles impair adhesion of airway epithelial cells to fibronectinThe silent codon change I507-ATC->ATT contributes to the severity of the ΔF508 CFTR channel dysfunctionA Role for Neutrophils in Viral Respiratory Disease.Detection of site-specific positive Darwinian selection on pandemic influenza A/H1N1 virus genome: integrative approaches.P2Y6 receptors are involved in mediating the effect of inactivated avian influenza virus H5N1 on IL-6 & CXCL8 mRNA expression in respiratory epithelium.Inhibition of lung fluid clearance and epithelial Na+ channels by chlorine, hypochlorous acid, and chloramines.ENaC activity and expression is decreased in the lungs of protein kinase C-α knockout miceA novel tumor necrosis factor-mediated mechanism of direct epithelial sodium channel activationMechanisms and clinical consequences of acute lung injury.CFTR and lung homeostasis.Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung.Influenza virus M2 targets cystic fibrosis transmembrane conductance regulator for lysosomal degradation during viral infectionNadph oxidase regulates alveolar epithelial sodium channel activity and lung fluid balance in vivo via O⁻₂ signalingAngiotensin II stimulates epithelial sodium channels in the cortical collecting duct of the rat kidneyRegulation of alveolar epithelial Na+ channels by ERK1/2 in chlorine-breathing mice.ENaCs and ASICs as therapeutic targets.Decreased Na(+) influx lowers hippocampal neuronal excitability in a mouse model of neonatal influenza infection.Role of epithelial sodium channels in the regulation of lung fluid homeostasisInfluenza infection induces host DNA damage and dynamic DNA damage responses during tissue regeneration.Macrophage-epithelial paracrine crosstalk inhibits lung edema clearance during influenza infection.Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo.Influenza matrix protein 2 alters CFTR expression and function through its ion channel activity.The Dual Role of TNF in Pulmonary Edema.Host cellular signaling induced by influenza virus.Role of glutathione in immunity and inflammation in the lung.Human CD8(+) T Cells Damage Non-infected Epithelial Cells During Influenza Virus Infection In Vitro.Influenza leaves a TRAIL to pulmonary edema.Mechanistic perspective of the oxido-immunopathologic resolution property of kolaviron in mice influenza pneumonitis.Reactive species and pulmonary edema.Nitric oxide inhibits highly selective sodium channels and the Na+/K+-ATPase in H441 cells.Influenza virus infection alters ion channel function of Airway and alveolar cells: Mechanisms and physiological sequelae.Intoxicated Na(+) channels. Focus on "ethanol stimulates epithelial sodium channels by elevating reactive oxygen species"Double-stranded RNA induces similar pulmonary dysfunction to respiratory syncytial virus in BALB/c mice.Novel mechanisms for crotonaldehyde-induced lung edema.Influenza A matrix protein M2 downregulates CFTR: inhibition of chloride transport by a proton channel of the viral envelope.Alveolar nonselective channels are ASIC1a/α-ENaC channels and contribute to AFC.Phosphatidyl Inositol 3 Kinase-Gamma Balances Antiviral and Inflammatory Responses During Influenza A H1N1 Infection: From Murine Model to Genetic Association in Patients.Redox Biology of Respiratory Viral Infections
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P2860
Influenza virus M2 protein inhibits epithelial sodium channels by increasing reactive oxygen species.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 13 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Influenza virus M2 protein inh ...... asing reactive oxygen species.
@en
Influenza virus M2 protein inh ...... asing reactive oxygen species.
@nl
type
label
Influenza virus M2 protein inh ...... asing reactive oxygen species.
@en
Influenza virus M2 protein inh ...... asing reactive oxygen species.
@nl
prefLabel
Influenza virus M2 protein inh ...... asing reactive oxygen species.
@en
Influenza virus M2 protein inh ...... asing reactive oxygen species.
@nl
P2093
P2860
P356
P1433
P1476
Influenza virus M2 protein inh ...... easing reactive oxygen species
@en
P2093
Ahmed Lazrak
Diana L Noah
James W Noah
Karen E Iles
Sadis Matalon
P2860
P304
P356
10.1096/FJ.09-135590
P407
P50
P577
2009-07-13T00:00:00Z