The role of mammalian cardiac t-tubules in excitation-contraction coupling: experimental and computational approaches.
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Systems biology and the virtual physiological humanAlterations in T-tubule and dyad structure in heart disease: challenges and opportunities for computational analysesNumerical analysis of Ca2+ signaling in rat ventricular myocytes with realistic transverse-axial tubular geometry and inhibited sarcoplasmic reticulumModeling effects of L-type ca(2+) current and na(+)-ca(2+) exchanger on ca(2+) trigger flux in rabbit myocytes with realistic T-tubule geometriesImpact of detubulation on force and kinetics of cardiac muscle contraction.Spatio-temporal oscillations of individual mitochondria in cardiac myocytes reveal modulation of synchronized mitochondrial clusters.T-tubule disease: Relationship between t-tubule organization and regional contractile performance in human dilated cardiomyopathy.Cardiac T-Tubule Microanatomy and Function.Multiscale modeling of calcium dynamics in ventricular myocytes with realistic transverse tubulesDifferent subcellular populations of L-type Ca2+ channels exhibit unique regulation and functional roles in cardiomyocytesTargeting cardiomyocyte Ca2+ homeostasis in heart failure.The interaction of Ca2+ with sarcomeric proteins: role in function and dysfunction of the heartMechanical unloading reverses transverse tubule remodelling and normalizes local Ca(2+)-induced Ca(2+)release in a rodent model of heart failureHeterogeneity of T-Tubules in Pig Hearts.Altered regional cardiac wall mechanics are associated with differential cardiomyocyte calcium handling due to nebulette mutations in preclinical inherited dilated cardiomyopathy.Emerging mechanisms of T-tubule remodelling in heart failure.Electromechanical coupling in the cardiac myocyte; stretch-arrhythmia feedback.Reversibility of T-tubule remodelling in heart failure: mechanical load as a dynamic regulator of the T-tubules.Do t-tubules play a role in arrhythmogenesis in cardiac ventricular myocytes?The transverse-axial tubular system of cardiomyocytes.Atrial myocytes demonstrate the diversity of cardiac calcium signalling.Effect of ion concentration changes in the limited extracellular spaces on sarcolemmal ion transport and Ca2+ turnover in a model of human ventricular cardiomyocyte.Non-linear dynamics of cardiac alternans: subcellular to tissue-level mechanisms of arrhythmia.Pericellular Ca(2+) recycling potentiates thrombin-evoked Ca(2+) signals in human platelets.Computational modelling of the initiation and development of spontaneous intracellular Ca2+ waves in ventricular myocytes.Loss of caveolin-3-dependent regulation of ICa in rat ventricular myocytes in heart failure.Ultrastructural maturation of human bone marrow mesenchymal stem cells-derived cardiomyocytes under alternative induction of 5-azacytidine.The structure and function of cardiac t-tubules in health and disease.The Cardiac Physiome: at the heart of coupling models to measurement
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The role of mammalian cardiac t-tubules in excitation-contraction coupling: experimental and computational approaches.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The role of mammalian cardiac ...... and computational approaches.
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The role of mammalian cardiac ...... and computational approaches.
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type
label
The role of mammalian cardiac ...... and computational approaches.
@en
The role of mammalian cardiac ...... and computational approaches.
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prefLabel
The role of mammalian cardiac ...... and computational approaches.
@en
The role of mammalian cardiac ...... and computational approaches.
@nl
P2093
P2860
P1476
The role of mammalian cardiac ...... and computational approaches.
@en
P2093
Clive H Orchard
Fabien Brette
Michal Pásek
P2860
P304
P356
10.1113/EXPPHYSIOL.2008.043984
P577
2009-03-18T00:00:00Z