Tipin/Tim1/And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion. - Wikidata - awgldk - TriplyDB

Tipin/Tim1/And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion.

Tipin/Tim1/And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion.

http://www.wikidata.org/entity/Q37418052

about

Cell cycle-dependent formation of Cdc45-Claspin complexes in human cells is compromized by UV-mediated DNA damage Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns New functions of Ctf18-RFC in preserving genome stability outside its role in sister chromatid cohesion.An Eco1-independent sister chromatid cohesion establishment pathway in S. cerevisiae.The Causes and Consequences of Topological Stress during DNA Replication Tim/Timeless, a member of the replication fork protection complex, operates with the Warsaw breakage syndrome DNA helicase DDX11 in the same fork recovery pathway WDHD1 modulates the post-transcriptional step of the centromeric silencing pathway The subunits of the S-phase checkpoint complex Mrc1/Tof1/Csm3: dynamics and interdependence.And-1 is required for homologous recombination repair by regulating DNA end resection.And-1 coordinates with CtIP for efficient homologous recombination and DNA damage checkpoint maintenance Linking chromosome duplication and segregation via sister chromatid cohesion Drosophila Ctf4 is essential for efficient DNA replication and normal cell cycle progression.Coordinated degradation of replisome components ensures genome stability upon replication stress in the absence of the replication fork protection complex RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks Timeless functions independently of the Tim-Tipin complex to promote sister chromatid cohesion in normal human fibroblasts Fork rotation and DNA precatenation are restricted during DNA replication to prevent chromosomal instability.Centromeric DNA replication reconstitution reveals DNA loops and ATR checkpoint suppression And-1 coordinates with Claspin for efficient Chk1 activation in response to replication stress The involvement of acidic nucleoplasmic DNA-binding protein (And-1) in the regulation of prereplicative complex (pre-RC) assembly in human cells.Sister chromatid cohesion Human Tim-Tipin complex affects the biochemical properties of the replicative DNA helicase and DNA polymerases.The human Tim-Tipin complex interacts directly with DNA polymerase epsilon and stimulates its synthetic activity.A prognostic signature of G(2) checkpoint function in melanoma cell lines.Replicating damaged DNA in eukaryotes.STAT3 interrupts ATR-Chk1 signaling to allow oncovirus-mediated cell proliferation.Replication fork dynamics and the DNA damage response.Local and global functions of Timeless and Tipin in replication fork protection.DNA replication and homologous recombination factors: acting together to maintain genome stability.DNA replication stress: from molecular mechanisms to human disease.Tipin functions in the protection against topoisomerase I inhibitor The replisome pausing factor Timeless is required for episomal maintenance of latent Epstein-Barr virus.Mta2 promotes Tipin-dependent maintenance of replication fork integrity.Human CST Facilitates Genome-wide RAD51 Recruitment to GC-Rich Repetitive Sequences in Response to Replication Stress.Ctf4 Links DNA Replication with Sister Chromatid Cohesion Establishment by Recruiting the Chl1 Helicase to the Replisome.Destabilization of the replication fork protection complex disrupts meiotic chromosome segregation.The human CTF4-orthologue AND-1 interacts with DNA polymerase α/primase via its unique C-terminal HMG box.MCM2-7-dependent cohesin loading during S phase promotes sister-chromatid cohesion.The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion

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P2860

Tipin/Tim1/And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion.

http://www.wikidata.org/entity/Q37418052

description

2009 nî lūn-bûn

@nan

2009年の論文

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2009年学术文章

@wuu

2009年学术文章

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2009年学术文章

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2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh

2009年學術文章

@zh-hant

name

Tipin/Tim1/And1 protein comple ...... and sister chromatid cohesion.

@en

Tipin/Tim1/And1 protein comple ...... and sister chromatid cohesion.

@nl

type

label

Tipin/Tim1/And1 protein comple ...... and sister chromatid cohesion.

@en

Tipin/Tim1/And1 protein comple ...... and sister chromatid cohesion.

@nl

prefLabel

Tipin/Tim1/And1 protein comple ...... and sister chromatid cohesion.

@en

Tipin/Tim1/And1 protein comple ...... and sister chromatid cohesion.

@nl

P1433

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P1433

The EMBO Journal

P1476

Tipin/Tim1/And1 protein comple ...... and sister chromatid cohesion.

@en

P2093

Alessia Errico

http://www.w3.org/2001/XMLSchema#string

Claudia Cosentino

http://www.w3.org/2001/XMLSchema#string

Teresa Rivera

http://www.w3.org/2001/XMLSchema#string

Tim Hunt

http://www.w3.org/2001/XMLSchema#string

P2860

The Orc4p and Orc5p subunits of the Xenopus and human origin recognition complex are related to Orc1p and Cdc6p

Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase

Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates

Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts

Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint

Wapl controls the dynamic association of cohesin with chromatin

Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway

Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function

The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement

Mcm10 and And-1/CTF4 recruit DNA polymerase alpha to chromatin for initiation of DNA replication

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23

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28

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Vincenzo Costanzo

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38070921

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19893489

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2775894

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