In vitro replication of hepatitis E virus (HEV) genomes and of an HEV replicon expressing green fluorescent protein
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The open reading frame 3 gene of hepatitis E virus contains a cis-reactive element and encodes a protein required for infection of macaquesIonic imbalance, in addition to molecular crowding, abates cytoskeletal dynamics and vesicle motility during hypertonic stress.Molecular Biology and Infection of Hepatitis E VirusTherapeutic targets for the treatment of hepatitis E virus infectionThe hepatitis E virus ORF3 protein regulates the expression of liver-specific genes by modulating localization of hepatocyte nuclear factor 4Review article: hepatitis E-a concise review of virology, epidemiology, clinical presentation and therapy.Risk Profile of Hepatitis E Virus from Pigs or Pork in Canada.Advances in hepatitis E - I: virology, pathogenesis and diagnosis.Mutations within potential glycosylation sites in the capsid protein of hepatitis E virus prevent the formation of infectious virus particles.Capped RNA transcripts of full-length cDNA clones of swine hepatitis E virus are replication competent when transfected into Huh7 cells and infectious when intrahepatically inoculated into pigs.Older men with unexplained hepatitis.Enhancement of interferon induction by ORF3 product of hepatitis E virus.Release of genotype 1 hepatitis E virus from cultured hepatoma and polarized intestinal cells depends on open reading frame 3 protein and requires an intact PXXP motif.Prevalence of hepatitis e virus in swine fed on kitchen residueHepatitis E virus inhibits type I interferon induction by ORF1 productsThe nucleotides on the stem-loop RNA structure in the junction region of the hepatitis E virus genome are critical for virus replication.Molecular biology and replication of hepatitis E virus.Cross-species infections of cultured cells by hepatitis E virus and discovery of an infectious virus-host recombinant.Intergenotypic chimeric hepatitis E viruses (HEVs) with the genotype 4 human HEV capsid gene in the backbone of genotype 3 swine HEV are infectious in pigs.A bicistronic subgenomic mRNA encodes both the ORF2 and ORF3 proteins of hepatitis E virusHepatitis E virus ORF2 protein over-expressed by baculovirus in hepatoma cells, efficiently encapsidates and transmits the viral RNA to naïve cells.Three amino acid mutations (F51L, T59A, and S390L) in the capsid protein of the hepatitis E virus collectively contribute to virus attenuation.Quantitative proteomics identifies host factors modulated during acute hepatitis E virus infection in the swine model.ORF3 protein of hepatitis E virus is not required for replication, virion assembly, or infection of hepatoma cells in vitro.Evidence of MAPK-JNK1/2 activation by hepatitis E virus ORF3 protein in cultured hepatoma cells.Hepatitis E virus replication requires an active ubiquitin-proteasome system.Adaptation of a genotype 3 hepatitis E virus to efficient growth in cell culture depends on an inserted human gene segment acquired by recombination.Endoplasmic Reticulum Stress Induced Synthesis of a Novel Viral Factor Mediates Efficient Replication of Genotype-1 Hepatitis E Virus.Rescue of a porcine anellovirus (torque teno sus virus 2) from cloned genomic DNA in pigs.Rescue of a genotype 4 human hepatitis E virus from cloned cDNA and characterization of intergenotypic chimeric viruses in cultured human liver cells and in pigs.Production of hepatitis E virus-like particles presenting multiple foreign epitopes by co-infection of recombinant baculovirusesThe hepatitis E virus ORF3 protein modulates epidermal growth factor receptor trafficking, STAT3 translocation, and the acute-phase response.Innate immune responses in human hepatocyte-derived cell lines alter genotype 1 hepatitis E virus replication efficiencies.The hepatitis E virus open reading frame 3 product interacts with microtubules and interferes with their dynamics.Hepatitis E virus genotype 1 infection of swine kidney cells in vitro is inhibited at multiple levelsHepatitis e: molecular virology and pathogenesis.Mutational analysis of hepatitis E virus ORF1 "Y-domain": Effects on RNA replication and virion infectivity.In vitro and in vivo mutational analysis of the 3'-terminal regions of hepatitis e virus genomes and repliconsEfficient cell culture systems for hepatitis E virus strains in feces and circulating blood.Hepatitis E: source and route of infection, clinical manifestations and new developments.
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In vitro replication of hepatitis E virus (HEV) genomes and of an HEV replicon expressing green fluorescent protein
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
In vitro replication of hepati ...... sing green fluorescent protein
@en
In vitro replication of hepatitis E virus
@nl
type
label
In vitro replication of hepati ...... sing green fluorescent protein
@en
In vitro replication of hepatitis E virus
@nl
prefLabel
In vitro replication of hepati ...... sing green fluorescent protein
@en
In vitro replication of hepatitis E virus
@nl
P2093
P2860
P1433
P1476
In vitro replication of hepati ...... sing green fluorescent protein
@en
P2093
Alicia Brockington
David A Stephany
Hanh Nguyen
Judith Graff
Robert H Purcell
Suzanne U Emerson
P2860
P304
P356
10.1128/JVI.78.9.4838-4846.2004
P407
P577
2004-05-01T00:00:00Z