Propagation of Saccharomyces cerevisiae [PSI+] prion is impaired by factors that regulate Hsp70 substrate binding
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Actin, Membrane Trafficking and the Control of Prion Induction, Propagation and Transmission in YeastModulation and elimination of yeast prions by protein chaperones and co-chaperonesYeast prions: structure, biology, and prion-handling systemsCuring of the [URE3] prion by Btn2p, a Batten disease-related protein.Hsp104, Hsp70 and Hsp40 interplay regulates formation, growth and elimination of Sup35 prions.The Hsp70/90 cochaperone, Sti1, suppresses proteotoxicity by regulating spatial quality control of amyloid-like proteins.Prion-impairing mutations in Hsp70 chaperone Ssa1: effects on ATPase and chaperone activities.CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progressionYeast prions are useful for studying protein chaperones and protein quality controlThe NatA acetyltransferase couples Sup35 prion complexes to the [PSI+] phenotypeUsing steered molecular dynamics to predict and assess Hsp70 substrate-binding domain mutants that alter prion propagationHsp110 chaperones regulate prion formation and propagation in S. cerevisiae by two discrete activities.The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative DiseasesNeuronal calcium sensor-1 (Ncs1p) is up-regulated by calcineurin to promote Ca2+ tolerance in fission yeast.Overexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis.Role for Hsp70 chaperone in Saccharomyces cerevisiae prion seed replication.Sti1 regulation of Hsp70 and Hsp90 is critical for curing of Saccharomyces cerevisiae [PSI+] prions by Hsp104.The hop-like stress-induced protein 1 cochaperone is a novel cell-intrinsic restriction factor for mitochondrial tombusvirus replication.Assessment of inactivating stop codon mutations in forty Saccharomyces cerevisiae strains: implications for [PSI] prion- mediated phenotypes.Independent regulation of Hsp70 and Hsp90 chaperones by Hsp70/Hsp90-organizing protein Sti1 (Hop1).Hsp40s specify functions of Hsp104 and Hsp90 protein chaperone machines.Molecular chaperones and the assembly of the prion Sup35p, an in vitro study.Hsp70 chaperones as modulators of prion life cycle: novel effects of Ssa and Ssb on the Saccharomyces cerevisiae prion [PSI+]Primate chaperones Hsc70 (constitutive) and Hsp70 (induced) differ functionally in supporting growth and prion propagation in Saccharomyces cerevisiae.De novo appearance and "strain" formation of yeast prion [PSI+] are regulated by the heat-shock transcription factor.N-terminal domain of yeast Hsp104 chaperone is dispensable for thermotolerance and prion propagation but necessary for curing prions by Hsp104 overexpressionProtein inheritance (prions) based on parallel in-register beta-sheet amyloid structures.Molecular chaperone Hsp104 can promote yeast prion generationHeterologous aggregates promote de novo prion appearance via more than one mechanism.Importance of the Hsp70 ATPase domain in yeast prion propagationHsp90-Associated Immunophilin Homolog Cpr7 Is Required for the Mitotic Stability of [URE3] Prion in Saccharomyces cerevisiae.Nucleotide exchange factors for Hsp70s are required for [URE3] prion propagation in Saccharomyces cerevisiae.Prions in yeast.Prokaryotic chaperones support yeast prions and thermotolerance and define disaggregation machinery interactionsPrions of yeast are genes made of protein: amyloids and enzymes.The role of Sse1 in the de novo formation and variant determination of the [PSI+] prion.Uncovering a region of heat shock protein 90 important for client binding in E. coli and chaperone function in yeast.Prions of fungi: inherited structures and biological rolesVariant-specific [PSI+] infection is transmitted by Sup35 polymers within [PSI+] aggregates with heterogeneous protein compositionFunctionally redundant isoforms of a yeast Hsp70 chaperone subfamily have different antiprion effects.
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Propagation of Saccharomyces cerevisiae [PSI+] prion is impaired by factors that regulate Hsp70 substrate binding
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2004
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Propagation of Saccharomyces c ...... gulate Hsp70 substrate binding
@en
Propagation of Saccharomyces c ...... ulate Hsp70 substrate binding.
@nl
type
label
Propagation of Saccharomyces c ...... gulate Hsp70 substrate binding
@en
Propagation of Saccharomyces c ...... ulate Hsp70 substrate binding.
@nl
prefLabel
Propagation of Saccharomyces c ...... gulate Hsp70 substrate binding
@en
Propagation of Saccharomyces c ...... ulate Hsp70 substrate binding.
@nl
P2093
P2860
P1476
Propagation of Saccharomyces c ...... gulate Hsp70 substrate binding
@en
P2093
Daniel C Masison
Seyung Chung
Youtao Song
P2860
P304
P356
10.1128/MCB.24.9.3928-3937.2004
P407
P50
P577
2004-05-01T00:00:00Z