Metallopeptide based mimics with substituted histidines approximate a key hydrogen bonding network in the metalloenzyme nickel superoxide dismutase

Metallopeptide based mimics with substituted histidines approximate a key hydrogen bonding network in the metalloenzyme nickel superoxide dismutase

Item
http://www.wikidata.org/entity/Q37424838
Bisamidate and mixed amine/amidate NiN2S2 complexes as models for nickel-containing acetyl coenzyme A synthase and superoxide dismutase: an experimental and computational study.Nickel superoxide dismutase: structural and functional roles of His1 and its H-bonding networkDipeptide-based models of nickel superoxide dismutase: solvent effects highlight a critical role to Ni-S bonding and active site stabilization.Use of metallopeptide based mimics demonstrates that the metalloprotein nitrile hydratase requires two oxidized cysteinates for catalytic activityUse of a metallopeptide-based mimic provides evidence for a proton-coupled electron-transfer mechanism for superoxide reduction by nickel-containing superoxide dismutase.Controlling the chiral inversion reaction of the metallopeptide Ni-asparagine-cysteine-cysteine with dioxygen.Embedding the Ni-SOD mimetic Ni-NCC within a polypeptide sequence alters the specificity of the reaction pathway.Prenatal and lactational lead exposure enhanced oxidative stress and altered apoptosis status in offspring rats' hippocampus.New insights into the mechanism of nickel superoxide degradation from studies of model peptides.Experimental and DFT Investigations Reveal the Influence of the Outer Coordination Sphere on the Vibrational Spectra of Nickel-Substituted Rubredoxin, a Model Hydrogenase Enzyme.
P2860

Metallopeptide based mimics with substituted histidines approximate a key hydrogen bonding network in the metalloenzyme nickel superoxide dismutase

Item
http://www.wikidata.org/entity/Q37424838
description
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Metallopeptide based mimics wi ...... me nickel superoxide dismutase
@en
Metallopeptide based mimics wi ...... e nickel superoxide dismutase.
@nl
type
label
Metallopeptide based mimics wi ...... me nickel superoxide dismutase
@en
Metallopeptide based mimics wi ...... e nickel superoxide dismutase.
@nl
prefLabel
Metallopeptide based mimics wi ...... me nickel superoxide dismutase
@en
Metallopeptide based mimics wi ...... e nickel superoxide dismutase.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Metallopeptide based mimics wi ...... me nickel superoxide dismutase
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932