Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been - Wikidata - awgldk - TriplyDB

Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been

Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been

http://www.wikidata.org/entity/Q37426801

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PGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase.Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1 MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis Statins promote the regression of atherosclerosis via activation of the CCR7-dependent emigration pathway in macrophages PROTEIN STRUCTURE. Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels.Species-specific dibutyl phthalate fetal testis endocrine disruption correlates with inhibition of SREBP2-dependent gene expression pathways Genotype and expression analysis of two inbred mouse strains and two derived congenic strains suggest that most gene expression is trans regulated and sensitive to genetic background.MicroRNAs in metabolism and metabolic disorders A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans.MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo Inhibition of SREBP transcriptional activity by a boron-containing compound improves lipid homeostasis in diet-induced obesity Oxysterols synergize with statins by inhibiting SREBP-2 in ovarian cancer cells Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.Design, synthesis and biological study of pinacolyl boronate-substituted stilbenes as novel lipogenic inhibitors.N-termini of fungal CSL transcription factors are disordered, enriched in regulatory motifs and inhibit DNA binding in fission yeast.Divergent interactions involving the oxidosqualene cyclase and the steroid-3-ketoreductase in the sterol biosynthetic pathway of mammals and yeasts.Transcriptional activation of low-density lipoprotein receptor gene by DJ-1 and effect of DJ-1 on cholesterol homeostasis Regulation of lipogenic gene expression by lysine-specific histone demethylase-1 (LSD1).Consequences of exchanging carbohydrates for proteins in the cholesterol metabolism of mice fed a high-fat diet s-Adenosylmethionine Levels Govern Innate Immunity through Distinct Methylation-Dependent Pathways.Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila Other ways to skin a cat: activating SREBP without Scap.Mammalian sirtuins and energy metabolism Distribution and functions of sterols and sphingolipids.Sirtuin 1 in lipid metabolism and obesity.Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition.Yeast sterol regulatory element-binding protein (SREBP) cleavage requires Cdc48 and Dsc5, a ubiquitin regulatory X domain-containing subunit of the Golgi Dsc E3 ligase Phylogenetic analysis and classification of the fungal bHLH domain.Endoproteolytic cleavage of TUG protein regulates GLUT4 glucose transporter translocation Hepatic growth hormone and glucocorticoid receptor signaling in body growth, steatosis and metabolic liver cancer development.Regulation of SREBP during hypoxia requires Ofd1-mediated control of both DNA binding and degradation.Regulation of the human prostacyclin receptor gene by the cholesterol-responsive SREBP1.Expanding roles for SREBP in metabolism Transcriptional regulation of T cell metabolism.Coordination of hypoxia adaptation and iron homeostasis in human pathogenic fungi.Of mice and men (and rats): phthalate-induced fetal testis endocrine disruption is species-dependent.SIRT1 and energy metabolism.Regulation of SREBP-Mediated Gene Expression.The Mediator Complex and Lipid Metabolism.Structural requirements for sterol regulatory element-binding protein (SREBP) cleavage in fission yeast

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Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been

http://www.wikidata.org/entity/Q37426801

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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2009年學術文章

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2009年學術文章

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name

Evolutionary conservation and ...... a long, strange tRIP it's been

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Evolutionary conservation and ...... long, strange tRIP it's been.

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type

label

Evolutionary conservation and ...... a long, strange tRIP it's been

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Evolutionary conservation and ...... long, strange tRIP it's been.

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prefLabel

Evolutionary conservation and ...... a long, strange tRIP it's been

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Evolutionary conservation and ...... long, strange tRIP it's been.

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Genes & Development

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Evolutionary conservation and ...... a long, strange tRIP it's been

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Peter J Espenshade

http://www.w3.org/2001/XMLSchema#string

Timothy F Osborne

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ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

Identification of cholesterol-regulating genes by targeted RNAi screening

A Mediator subunit, MDT-15, integrates regulation of fatty acid metabolism by NHR-49-dependent and -independent pathways in C. elegans

Dimerization of sterol regulatory element-binding protein 2 via the helix-loop-helix-leucine zipper domain is a prerequisite for its nuclear localization mediated by importin beta

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2578-2591

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scholarly article

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10.1101/GAD.1854309

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22

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23

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2009-11-01T00:00:00Z

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40026507

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19933148

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2779761

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