The histone deacetylase inhibitor, MS-275 (entinostat), downregulates c-FLIP, sensitizes osteosarcoma cells to FasL, and induces the regression of osteosarcoma lung metastases.
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The narrow-spectrum HDAC inhibitor entinostat enhances NKG2D expression without NK cell toxicity, leading to enhanced recognition of cancer cellsHistone Deacetylases in Bone Development and Skeletal Disorders.Molecular profiling of childhood cancer: Biomarkers and novel therapiesSensitivity of osteosarcoma cells to HDAC inhibitor AR-42 mediated apoptosis.The histone deacetylase inhibiting drug Entinostat induces lipid accumulation in differentiated HepaRG cells.Proteomics of osteosarcoma.Advances in therapy for pediatric sarcomas.Prognostic and therapeutic relevance of FLIP and procaspase-8 overexpression in non-small cell lung cancer.Therapeutic applications of histone deacetylase inhibitors in sarcoma.Target-based drug discovery for [Formula: see text]-globin disorders: drug target prediction using quantitative modeling with hybrid functional Petri nets.Expression patterns of class I histone deacetylases in osteosarcoma: a novel prognostic marker with potential therapeutic implications.
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P2860
The histone deacetylase inhibitor, MS-275 (entinostat), downregulates c-FLIP, sensitizes osteosarcoma cells to FasL, and induces the regression of osteosarcoma lung metastases.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on May 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The histone deacetylase inhibi ...... osteosarcoma lung metastases.
@en
The histone deacetylase inhibi ...... osteosarcoma lung metastases.
@nl
type
label
The histone deacetylase inhibi ...... osteosarcoma lung metastases.
@en
The histone deacetylase inhibi ...... osteosarcoma lung metastases.
@nl
prefLabel
The histone deacetylase inhibi ...... osteosarcoma lung metastases.
@en
The histone deacetylase inhibi ...... osteosarcoma lung metastases.
@nl
P2093
P2860
P1476
The histone deacetylase inhibi ...... osteosarcoma lung metastases.
@en
P2093
Eugenie S Kleinerman
John Stewart
Krithi Rao-Bindal
Nadezhda V Koshkina
P2860
P304
P356
10.2174/1568009611313040005
P577
2013-05-01T00:00:00Z