The macrocyclic peptide natural product CJ-15,208 is orally active and prevents reinstatement of extinguished cocaine-seeking behavior.
about
Salvinorin A, a kappa-opioid receptor agonist hallucinogen: pharmacology and potential template for novel pharmacotherapeutic agents in neuropsychiatric disordersStress-Induced Reinstatement of Drug Seeking: 20 Years of Progress.Alanine analogues of [D-Trp]CJ-15,208: novel opioid activity profiles and prevention of drug- and stress-induced reinstatement of cocaine-seeking behaviour.Synthesis and characterization of a dual kappa-delta opioid receptor agonist analgesic blocking cocaine reward behaviorThe macrocyclic tetrapeptide [D-Trp]CJ-15,208 produces short-acting κ opioid receptor antagonism in the CNS after oral administration.Development of a robust, sensitive and selective liquid chromatography-tandem mass spectrometry assay for the quantification of the novel macrocyclic peptide kappa opioid receptor antagonist [D-Trp]CJ-15,208 in plasma and application to an initial pTryptophan-Containing Non-Cationizable Opioid Peptides - a new chemotype with unusual structure and in vivo activity.Differential regulation of mGlu5 R and ΜOPr by priming- and cue-induced reinstatement of cocaine-seeking behaviour in mice.Macrocyclic peptides decrease c-Myc protein levels and reduce prostate cancer cell growth.
P2860
Q26781580-D5EBBEF1-6CEA-4253-9692-67BA794425F9Q30366964-0B1E897C-9031-48A4-B9E5-E6F65A18CC95Q33842725-934DF4DD-2339-4398-9328-4C4D7A00C97BQ36296493-D44B3768-82D2-47B1-81C6-A171A47A7D03Q36836438-DFA7882C-2441-4D92-AB97-02ECB71EC63FQ42408786-26108A85-D014-4ABC-9D1B-FB1E88CC854AQ44350759-1F38D30A-0707-402A-82EB-AB3A184181BFQ48006822-FBE9D9C4-4E9F-4E14-AF7F-5C4B8309D01EQ48151505-85DCDD43-0C8D-421F-B929-CDE36920F900
P2860
The macrocyclic peptide natural product CJ-15,208 is orally active and prevents reinstatement of extinguished cocaine-seeking behavior.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 17 January 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The macrocyclic peptide natura ...... shed cocaine-seeking behavior.
@en
The macrocyclic peptide natura ...... shed cocaine-seeking behavior.
@nl
type
label
The macrocyclic peptide natura ...... shed cocaine-seeking behavior.
@en
The macrocyclic peptide natura ...... shed cocaine-seeking behavior.
@nl
prefLabel
The macrocyclic peptide natura ...... shed cocaine-seeking behavior.
@en
The macrocyclic peptide natura ...... shed cocaine-seeking behavior.
@nl
P2093
P2860
P356
P1476
The macrocyclic peptide natura ...... shed cocaine-seeking behavior.
@en
P2093
Jane V Aldrich
Jay P McLaughlin
Michelle L Ganno
Nicolette C Ross
Sanjeewa N Senadheera
Shainnel O Eans
P2860
P304
P356
10.1021/NP300697K
P577
2013-01-17T00:00:00Z