Expression of cyclin D1 in epithelial tissues of transgenic mice results in epidermal hyperproliferation and severe thymic hyperplasia.
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Cyclin D- and E-dependent kinases and the p57(KIP2) inhibitor: cooperative interactions in vivoSignalling in the epidermis: the E2F cell cycle regulatory pathway in epidermal morphogenesis, regeneration and transformationRegulation of epidermal differentiation by a Distal-less homeodomain gene.Thymic and Postthymic Regulation of Naïve CD4(+) T-Cell Lineage Fates in Humans and Mice ModelsD-type Cyclins are important downstream effectors of cytokine signaling that regulate the proliferation of normal and neoplastic mammary epithelial cells.Cyclins: roles in mitogenic signaling and oncogenic transformationTbata modulates thymic stromal cell proliferation and thymus functionInsights into cancer from transgenic mouse models.A mitosis block links active cell cycle with human epidermal differentiation and results in endoreplication.Walleye retroviruses associated with skin tumors and hyperplasias encode cyclin D homologs.The murine gammaherpesvirus 68 v-cyclin gene is an oncogene that promotes cell cycle progression in primary lymphocytes.Cell cycle regulators: mechanisms and their role in aetiology, prognosis, and treatment of cancer.Overexpression of transcription factor sp2 inhibits epidermal differentiation and increases susceptibility to wound- and carcinogen-induced tumorigenesis.Regeneration of the aged thymus by a single transcription factor.Genetic mosaics reveal both cell-autonomous and cell-nonautonomous function of murine p27Kip1Nasopharyngeal carcinoma--review of the molecular mechanisms of tumorigenesis.Sequence and chromosomal context effects on variegated expression of keratin 5/lacZ constructs in stratified epithelia of transgenic mice.Cell cycle dysregulation in oral cancer.A mouse model of human oral-esophageal cancer.Deregulated expression of insulin-like growth factor 1 in prostate epithelium leads to neoplasia in transgenic mice.Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivoComparative pathogenesis of epsilonretroviruses.Transgenic expression of cyclin-dependent kinase 4 results in epidermal hyperplasia, hypertrophy, and severe dermal fibrosis.Squamous epithelial proliferation induced by walleye dermal sarcoma retrovirus cyclin in transgenic miceCombined effect of cyclin D3 expression and abrogation of cyclin D1 prevent mouse skin tumor developmentCyclin D2 overexpression in transgenic mice induces thymic and epidermal hyperplasia whereas cyclin D3 expression results only in epidermal hyperplasia.The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines.Animal models of psoriasis.Acerola (Malpighia emarginata DC.) Juice Intake Suppresses UVB-Induced Skin Pigmentation in SMP30/GNL Knockout Hairless Mice.RB inactivation in keratin 18 positive thymic epithelial cells promotes non-cell autonomous T cell hyperproliferation in genetically engineered mice.CDK4 regulation by TNFR1 and JNK is required for NF-kappaB-mediated epidermal growth controlThe mysterious human epidermal cell cycle, or an oncogene-induced differentiation checkpoint.Cyclin A is a prognostic indicator in early stage breast cancer with and without tamoxifen treatment.Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression.Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b (CCND1b)Concerted overexpression of the genes encoding p21 and cyclin D1 is associated with growth inhibition and differentiation in various carcinomas.FM807, a curcumin analogue, shows potent antitumor effects in nasopharyngeal carcinoma cells by heat shock protein 90 inhibition.Cycling up the epidermis: reconciling 100 years of debate.Expression of cell cycle and apoptosis regulators in thymus and thymic epithelial tumors.Helicobacter pylori activates the cyclin D1 gene through mitogen-activated protein kinase pathway in gastric cancer cells.
P2860
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P2860
Expression of cyclin D1 in epithelial tissues of transgenic mice results in epidermal hyperproliferation and severe thymic hyperplasia.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Expression of cyclin D1 in epi ...... and severe thymic hyperplasia.
@en
Expression of cyclin D1 in epi ...... and severe thymic hyperplasia.
@nl
type
label
Expression of cyclin D1 in epi ...... and severe thymic hyperplasia.
@en
Expression of cyclin D1 in epi ...... and severe thymic hyperplasia.
@nl
prefLabel
Expression of cyclin D1 in epi ...... and severe thymic hyperplasia.
@en
Expression of cyclin D1 in epi ...... and severe thymic hyperplasia.
@nl
P2093
P2860
P356
P1476
Expression of cyclin D1 in epi ...... and severe thymic hyperplasia.
@en
P2093
A I Robles
I B Gimenez-Conti
J L Jorcano
R B Whalin
R Murillas
P2860
P304
P356
10.1073/PNAS.93.15.7634
P407
P577
1996-07-01T00:00:00Z